Empirico

Empirico

Develops medicines using human genetic data

Overview

Empirico uses human genetics and large biological datasets to discover and develop new medicines, focusing on target discovery and collaborations. Its Precision Insights Platform analyzes genetic and health data from millions of individuals using curated data, custom models, and proprietary algorithms to generate and rank high-confidence therapeutic hypotheses. It differentiates itself by grounding drug targets in naturally occurring genetic variation and by pairing a large dataset with partner-driven experiments (e.g., AbCellera) to validate hypotheses. Its goal is to improve the success rate of drug development by identifying validated targets and translating them into medicines through collaborations.

About Empirico

Simplify's Rating
Why Empirico is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & Analytics

Enterprise Software

Biotechnology

Healthcare

Company Size

51-200

Company Stage

Series B

Total Funding

$74.7M

Headquarters

San Diego, California

Founded

2017

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Simplify's Take

What believers are saying

  • GSK's October 28, 2025 deal validates Empirico's genetics engine and siRNA platform.
  • Ionis partnership history and AbCellera expansion show repeatable external demand for its targets.
  • Updated 2026 pipeline still lists EMP-CNS, preserving a second shot beyond COPD.

What critics are saying

  • GSK now owns EMP-012 commercialization after phase I, shrinking Empirico's near-term value capture.
  • EMP-CNS remains IND-enabling, leaving Empirico dependent on one clinical program.
  • If EMP-012 disappoints, Empirico loses its only disclosed clinical validation and partnership leverage.

What makes Empirico unique

  • Empirico pairs human genetics target discovery with siRNA design across Precision Insights and siRCH.
  • EMP-012 is a phase I COPD asset targeting a novel inflammatory pathway.
  • GSK kept worldwide development rights but still paid Empirico $85 million upfront.

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Funding

Total Funding

$74.7M

Above

Industry Average

Funded Over

3 Rounds

Series B funding is typically for startups that have proven their business model and need more funding to expand rapidly—often by entering new markets or adding more products. Investors are usually venture capital firms that specialize in later-stage investments.
Series B Funding Comparison
Above Average

Industry standards

$35M
$45M
Linktree
$45.2M
Empirico
$65M
Substack
$100M
ClickUp

Growth & Insights

Headcount

6 month growth

0%

1 year growth

0%

2 year growth

17%

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