GGlobal Brain is a venture capital firm that provides money and strategic help to startups around the world. It backs early-stage to growth-stage companies across tech, health, and enterprise sectors, using equity investments and hands-on support. The firm’s approach combines funding with strategic guidance, operational assistance, and access to a wide network of industry connections, all delivered by a diverse team. Unlike firms that only fund, Global Brain emphasizes speed, careful decision-making, and a focus on people-centered transformation, aiming to help portfolio companies scale quickly while driving social impact. Its goal is to grow innovative startups, create value for investors, and promote positive social change through entrepreneurship.
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Industries
Company Size
51-200
Company Stage
N/A
Total Funding
$5.3B
Headquarters
Tokyo, Japan
Founded
2021
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Total Funding
$5.3B
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Global Brain has made an additional investment in LIFESCAPES, a Japanese company that develops rehabilitation devices using Brain-Machine Interface/Brain-Computer Interface (BMI/BCI) technology. It invested through its Canon Marketing Japan MIRAI Fund. The amount was not disclosed. LIFESCAPES builds on more than a decade of research at Keio University's Ushiba Laboratory. Its devices read the patient's brain activity through scalp sensors and move a motorised orthosis on the paralysed fingers in real time, aiming to help the brain rebuild neural circuits. The company sells a medical-grade device for hospitals and clinics, approved by regulators in 2024, and a training device for long-term care and self-pay facilities. Global Brain first invested in June 2022 through its JGC MIRAI Innovation Fund. It will support LIFESCAPES' growth with Canon Marketing Japan Inc.
Global Brain has led an investment in AirMembrane Corporation, a developer and manufacturer of graphene EUV pellicles, through its Global Brain Flagship Fund IX. TAKANAWA Gateway Global Co-Benefits Fund L.P. joined for the first time, and Shinhan-GB FutureFlow Fund L.P. made a follow-on investment. EUV pellicles shield photomasks from particle contamination and strongly affect semiconductor yield. Meeting demands for high transmittance, heat dissipation, chemical stability, and mechanical strength at once is a major technical challenge. AirMembrane uses continuous synthesis and automated transfer technology developed at the National Institute of Advanced Industrial Science and Technology to mass produce graphene pellicles. The automated process removes microscopic defects. The funds will go toward building manufacturing capabilities and hiring engineers and business staff ahead of pilot production and mass production lines.
Starlight Engine, a Japanese fusion energy startup, has signed an investment agreement with the Takanawa Gateway Chikyu-eki Fund. East Japan Railway Company (JR East) is the fund's main limited partner, and Global Brain operates it. The amount was not disclosed. The startup will use the investment to speed up engineering design, research, site and regulatory work, and supply chain building for its FAST (Fusion by Advanced Superconducting Tokamak) project. FAST aims to demonstrate fusion power generation in the 2030s. Starlight Engine was founded in April 2025 as a group company of Kyoto Fusioneering. Its design work is under way, and the conceptual design is complete. The fund will lend its urban development expertise and assets to the project.
Global Brain has invested in WED, Inc. (WED), a company that operates a purchase data platform powered by its receipt-cashback app ONE and provides marketing…
Global Brain has made an additional investment in Essen through its TAKANAWA GATEWAY Global Co-Benefits Fund as lead investor. The Japanese company operates a mobility data platform that leverages movement data from vehicles like taxis and delivery trucks for advertising delivery and infrastructure inspection. Essen provides advertising via vehicles with rooftop signage and is developing technology to detect water pipe leaks using in-vehicle infrared sensors and AI analysis. Advertising vehicles now operate in Gunma and Fukuoka prefectures, whilst the company is piloting leak detection technology with multiple local governments. Essen was selected as a finalist in TAKANAWA PITCH at GATEWAY Tech TAKANAWA 2025. Global Brain previously invested in Essen through Shinhan-GB FutureFlow Fund in May 2024.
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Industries
Company Size
51-200
Company Stage
N/A
Total Funding
$5.3B
Headquarters
Tokyo, Japan
Founded
2021
Find jobs on Simplify and start your career today
We update Global Brain's jobs every few hours, so check again soon!Browse all jobs