IIronwood develops and commercializes medicines for gastrointestinal diseases, with a focus on irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC). Its therapies aim to alleviate GI symptoms and improve GI function through medicines developed via research and development and supported by strategic partnerships. The company differentiates itself through deep GI biology expertise and collaborations that help bring differentiated products to patients in a competitive biopharma market. Its goal is to deliver effective GI medicines that provide value to patients, healthcare providers, and shareholders, enabling ongoing progress in GI disease therapies.
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Industries
Company Size
201-500
Company Stage
IPO
Headquarters
Boston, MA
Founded
1998
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Total Funding
$634M
Above
Industry Average
Funded Over
10 Rounds
Ironwood Pharmaceuticals raised its 2026 outlook after third-quarter sales of its gastrointestinal drug LINZESS reached $325 million. Better net pricing and 5% year-over-year growth in prescription demand drove the result. The company now expects US LINZESS net sales of $1.2 billion to $1.25 billion, up $50 million from its earlier forecast. It lifted total revenue guidance to $485 million to $510 million and expects adjusted EBITDA above $350 million. Third-quarter revenue was $133 million, with record adjusted EBITDA of $98 million. Ironwood paid down $60 million of debt and expects to end 2026 with less than $300 million outstanding. Its Phase 3 apraglutide trial is expected to reach primary completion in October 2028, supporting a possible regulatory submission in 2029.
Ironwood promoting commercial chief in planned CEO succession. Plus: Former Novo CEO to become Lundbeck's chair; FDA official takes position amid BetaNova merger; and more. By BioCentury Staff October 20, 2026 2:34 PM PDT Ironwood Pharmaceuticals Inc. (NASDAQ:IRWD) said Chief Commercial Officer Tammi Gaskins will ascend to the company's CEO role upon the planned retirement of Tom McCourt on Jan. 1, 2027. McCourt, who joined the company in 2009, had taken the CEO spot in 2021 after serving as Ironwood's CCO. He led the company's 2023 acquisition of VectivBio Holding AG, which gave it gastrointestinal candidate apraglutide... Your competitors are already reading this Don't make your next decision without this analysis. Trusted by biotech, pharma, and investment leaders to move first on trial data, financings, and regulatory shifts. Benchmark any deal against $2.25T in tracked biopharma transactions 25,000+ deals, 4,600+ discontinued products, 1,300+ milestones, and more Spot emerging targets before they hit industry pipelines Query BioCentury directly inside the AI tools you already use Never miss the next one Full access to this article, BCIQ data, AI Connectors, and everything BioCentury publishes. Need just this one Article text only: no BCIQ data, AI Connectors, deal comparables, or coverage as the story develops.
Ironwood Pharmaceuticals, Inc. announces Board changes. Published on 10/16/2026 at 10:36 am EDT S&P Capital IQ Ironwood Pharmaceuticals, Inc. increased the size of the Board from eight to nine directors and elected Tammi Gaskins as a director, in each case, effective as of January 1, 2027. Mr. McCourt will continue to serve as a director on the Board following his retirement as Chief Executive Officer. Tammi has been a leader in Ironwood's commercial organization since joining the company in 2020 playing a critical role establishing LINZESS as the number one prescribed brand in the U.S. for the treatment of patients with irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC). She has also led commercial development efforts for apraglutide, a potential best-in-class, once-weekly GLP-2 analog in Phase 3 development for the treatment of adults with short bowel syndrome with intestinal failure (SBS-IF). Prior to joining Ironwood, Tammi held commercial leadership roles of increasing responsibilities during a 20-year tenure at AstraZeneca. Tom joined Ironwood as its first Chief Commercial Officer helping to shape the clinical profile of LINZESS to enable its commercial success. Building the commercial organization from the ground up, Tom and the team collaborated closely with multiple LINZESS partners over the years to grow it into a blockbuster brand. After becoming CEO in 2021, he led the effort to acquire VectivBio bringing apraglutide to Ironwood's late-stage pipeline. Before Ironwood, Tom made significant contributions to the commercial and drug development efforts for several market-leading brands at Merck, Astra Merck, AstraZeneca, Novartis and Amgen. (C) S&P Capital IQ - 2026
Ironwood Pharmaceuticals reported stronger second-quarter results, with LINZESS US sales rising 14% to $282.3 million. The company raised its 2026 LINZESS guidance to $1.15 billion-$1.2 billion. Ironwood began enrolling patients in the confirmatory Phase III STARS-2 trial for apraglutide, a treatment for short bowel syndrome with intestinal failure. The company is working to accelerate recruitment. The pharmaceutical firm repaid $200 million in convertible notes and raised its 2026 revenue guidance to $460 million-$485 million. Adjusted EBITDA is expected to exceed $310 million. Chief executive Thomas McCourt said the company remains focused on maximising LINZESS performance, advancing apraglutide, and delivering sustained profitability and cash flow.
Ironwood Pharmaceuticals has raised its full-year 2026 financial guidance following strong second-quarter results. The company now expects LINZESS U.S. net sales of $1.15–$1.20 billion, representing over 30% year-over-year growth, with total revenue guidance raised to $460–$485 million and adjusted EBITDA to greater than $310 million. In Q2 2026, LINZESS U.S. net sales reached $282 million, whilst year-to-date sales hit $555 million, marking 44% year-over-year growth. The company reported total revenue of $113 million, GAAP net income of $51 million, and adjusted EBITDA of $83 million for the quarter. Ironwood repaid $200 million in convertible notes using cash on hand and has begun actively recruiting patients for its confirmatory Phase 3 STARS-2 trial of apraglutide for short bowel syndrome with intestinal failure.
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We're working on gathering enough insights on this company, check back soon!
Industries
Company Size
201-500
Company Stage
IPO
Headquarters
Boston, MA
Founded
1998
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