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Overview
Matterworks applies artificial intelligence to metabolomics to make mass spectrometry data easier to analyze. It offers a model-as-a-service platform that lets researchers identify and quantify metabolites from raw data, using its Large Spectral Model (LSM) to interpret molecular-omic information. Its Pyxis product provides turn-key, near real-time metabolite profiling, reducing analysis time and enabling faster decision-making in therapeutic research, biomanufacturing, crop science, and animal health. By delivering end-to-end AI for omics data, Matterworks aims to lower costs and broaden access to advanced metabolomics, helping life sciences R&D move from data to actionable insight more quickly.
About Matterworks
Industries
Data & Analytics
AI & Machine Learning
Biotechnology
Healthcare
Company Size
11-50
Company Stage
Seed
Total Funding
$13.8M
Headquarters
Somerville, Massachusetts
Founded
2019
Simplify's Take
What believers are saying
- Series A in June 2025 from Lewis & Clark and OMX funds MaaS expansion.
- Pyxis beta with top pharma validates applications in biomarkers and cell-line development.
- New CFO Paul Stone and CSO Jennifer Campbell accelerate partnerships.
What critics are saying
- Metabolon captures market share with broader assays in 12-24 months.
- Recursion poaches ML experts from 25-person team in 12-18 months.
- $15.9M runway ends in 18-24 months amid 2026 biotech downturn.
What makes Matterworks unique
- Matterworks' Pyxis uses Large Spectral Models for untargeted metabolomics annotation.
- Pyxis reduces LC-MS analysis from weeks to five minutes per sample.
- MaaS model delivers AI-driven metabolite insights across biomanufacturing and therapeutics.
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Funding
Total Funding
$13.8M
Above
Industry Average
Funded Over
3 Rounds
Industry standards
Benefits
Health Insurance
Dental Insurance
Vision Insurance
Long-term Disability Insurance
Short-term Disability Insurance
Life Insurance
401(k) Retirement Plan
Stock Options
Flexible Work Hours
Unlimited Paid Time Off
Remote Work Options
Paid Vacation
Paid Holidays
Commuter Benefits
Professional Development Budget
Conference Attendance Budget
Tuition Reimbursement
Growth & Insights and Company News
6 month growth
↑ 6%1 year growth
↑ 2%2 year growth
↑ 4%Matterworks, a frontier AI company providing predictive biology tools for life sciences, has appointed Paul Stone as Chief Financial Officer and Head of Corporate Development. Stone brings 28 years of experience in venture capital and operating roles, most recently as partner at 5AM Ventures and previously as CFO at IDEAYA Biosciences. The Somerville, Massachusetts-based company's platform uses Large Spectral Models for machine interpretation of biochemical data to predict complex biological outcomes. Matterworks has demonstrated applications across target identification, compound optimisation, biomarker discovery, patient stratification, cell-line development and bioprocess development. CEO Jack Geremia said the appointment supports expansion of commercial and partnership development activities as the company engages with pharmaceutical and biotech firms to enhance efficiency in research, development and manufacturing.
Matterworks, Inc., based in Somerville, Mass., announced securing Series A funding to advance machine intelligence for predictive biology. The financing round was led by Lewis & Clark Partners and OMX Ventures, with participation from Pillar VC, Germin8 Ventures, and Intermountain Ventures.
/PRNewswire/ -- Matterworks, Inc., the category-defining pioneer unlocking unstructured molecular data for predictive biology, today announces new Series A...
SOMERVILLE, Mass., May 2, 2024 /PRNewswire/ -- Matterworks, Inc., whose foundational AI platform and predictive biology applications accelerate life sciences discovery and development, today announces additions to its leadership team.Matterworks is pleased to announce the appointments of Jennifer M. Campbell, Ph.D. to the position of Chief Scientific Officer and Niall O'Connor to the position of Chief Technology Officer.Dr. Campbell is a distinguished leader in mass spectrometry and molecular analysis, bringing 25 years of expertise to the role. She joined Matterworks from Novartis Institutes of Biomedical Research in 2021 to lead R&D from initial product conceptualization through development and early customer testing. In late 2023 Dr
In 2023, agrifoodtech represented just 5.5% of all venture capital sector dollars, down from 6.7% in 2022 and 7.6% in 2021, despite the fact that the food ag industry accounts for almost a fifth of global GDP and is a major contributor to climate change. And with funding continuing to decline, is it time to panic?. At the recent World Agri-Tech innovation summit in San Francisco, we caught up with Michael Lavin, managing partner at Germin8 Ventures, a long-time investor in the sector to discuss:Where are we in the current down cycle?. What is getting funded now and why? What is Germin8 excited about?
Matterworks is Hiring for 3 Jobs on Simplify!
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About Matterworks
Industries
Data & Analytics
AI & Machine Learning
Biotechnology
Healthcare
Company Size
11-50
Company Stage
Seed
Total Funding
$13.8M
Headquarters
Somerville, Massachusetts
Founded
2019
Matterworks is Hiring for 3 Jobs on Simplify!
Find jobs on Simplify and start your career today