NUS Enterprise has rebranded as NUSX, expanding its role as an integrated venture-building and IP commercialisation platform. The transformation aligns with Singapore's Research, Innovation and Enterprise 2030 plan, which commits S$37 billion over five years. NUSX is establishing global outposts beyond Silicon Valley to include Munich and Shanghai, providing deep tech ventures with access to overseas markets, partners and investors. The platform launched Nova, an AI-powered engine developed with Zima Labs that analyses patents and identifies commercial opportunities in minutes, drawing on over 20,000 NUS patents and 9,000 research projects. NUSX has partnered with UnternehmerTUM to strengthen its presence in Munich's innovation ecosystem. The platform focuses on four deep tech areas: Logic, Pulse, Resilience and Matter. By 2035, NUSX aims to create at least one venture generating over $100 million in annual revenue.

US venture capital firms Playground Global and Matter Venture Partners have joined NUS Enterprise's US$117 million VC Programme, gaining access to Singapore's deep tech startup ecosystem. The partnerships will connect promising Singaporean startups in AI, biotech, quantum technologies and advanced materials with US markets and venture networks. NUS Enterprise will establish its first global outpost at Playground Global's 70,000-square-foot Silicon Valley facility, The Studio, providing NUS-backed founders with laboratories, prototyping workshops and market exposure to validate technologies and refine product-market fit. The NUS VC Programme comprises US$39 million in investments across selected VC firms and US$78 million reserved for co-investments in NUS-affiliated startups. Since 2001, NUS Enterprise has nurtured 10 unicorns and over 3,000 startups.