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Overview
OneSkin develops premium skincare products powered by OS-01, a peptide that targets cellular senescence to slow skin aging. OS-01 works by preventing buildup of senescent cells, supporting tissue repair, and boosting collagen and hyaluronic acid markers, with lab tests showing thicker epidermis and reduced biological age in skin models. The company differentiates itself by grounding its products in senotherapy science, validating effects in lab models, and combining a direct-to-consumer, subscription-driven model with Amazon and professional channels. Its goal is to expand internationally, develop new products, and advance clinical studies to further validate OS-01 and extend skin health.
About OneSkin
Industries
Biotechnology
Healthcare
Consumer Goods
Company Size
51-200
Company Stage
Series A
Total Funding
$40M
Headquarters
San Francisco, California
Founded
2016
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Simplify's Take
What believers are saying
- Prelude Growth invested $20 million in August 2025, funding expansion and clinical trials.
- OneSkin added a VP of growth marketing and creative director in 2025.
- Public reporting targeted $40-$50M revenue in 2025 and retail debut in 2027.
What critics are saying
- OS-01 depends on consumer trust; failed clinical validation kills the premium story.
- Heavy DTC reliance leaves OneSkin exposed if paid-search costs rise or Meta ads weaken.
- If OS-01 loses scientific credibility, OneSkin becomes an expensive private-label skincare brand.
What makes OneSkin unique
- OS-01 peptide targets cellular senescence, a category few skincare brands claim.
- OneSkin sells science-led topical products across face, body, eyes, lips, and hair.
- Founders are Brazilian scientists with immunology, stem-cell, and bioinformatics expertise from 2016.
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Funding
Total Funding
$40M
Above
Industry Average
Funded Over
4 Rounds
Industry standards
Benefits
Health Insurance
Dental Insurance
Vision Insurance
Health Savings Account/Flexible Spending Account
401(k) Company Match
Remote Work Options
Home Office Stipend
Wellness Program
Growth & Insights and Company News
6 month growth
↓ -1%1 year growth
↓ -1%2 year growth
↑ 0%The biotech skin care brand has secured Series A investment from growth equity firm Prelude Growth Partners to secure its ‘leadership in skin longevity’
Oneskin has raised $20 million from Prelude Growth Partners to boost product development, clinical trials, and leadership hires. The investment replaces a previous backer as Oneskin aims for $40–$50 million in revenue this year. Known for its OS-01 peptide skincare, the brand focuses on DTC sales and subscriptions. Prelude's investment supports Oneskin's science-backed model and plans for retail expansion by 2027. Recent hires include a VP of growth marketing and a creative director.
OneSkin, a longevity-focused skincare brand, has closed a series A investment round led by Selva Ventures, PLUS Capital, Unilever Ventures, and others, raising a total of $20 million. The funding will support growth, R&D, hiring, and new sales channels. Notable investors include Camila Alves McConaughey and Kevin Rose. The brand's core ingredient, OS-01, targets cellular aging and offers protection from UV and collagen breakdown. CEO Carolina Reis Oliveira emphasizes empowering consumers with information.
OneSkin has secured $7 million in Series A funding, led by Selva Ventures with participation from Unilever Ventures, Plus Capital, and others, including Camila Alves McConaughey. This brings OneSkin's total funding to $20 million. The funding will support clinical studies, team expansion, product assortment growth, and marketing efforts. CEO Carolina Reis Oliveira notes the company's profitability and aims for sustainable growth with positive EBITDA.
San Francisco, CA - According to filings with the U.S. Securities and Exchange Commission, OneSkin is raising $12,412,714.00 in new funding. Sources indicate as part of senior management President, Carolina deOliveira played a key role
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About OneSkin
Industries
Biotechnology
Healthcare
Consumer Goods
Company Size
51-200
Company Stage
Series A
Total Funding
$40M
Headquarters
San Francisco, California
Founded
2016
OneSkin is Hiring for 1 Jobs on Simplify!
Find jobs on Simplify and start your career today