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Overview
OneSkin develops premium skincare products powered by OS-01, a peptide that targets cellular senescence to slow skin aging. OS-01 works by preventing buildup of senescent cells, supporting tissue repair, and boosting collagen and hyaluronic acid markers, with lab tests showing thicker epidermis and reduced biological age in skin models. The company differentiates itself by grounding its products in senotherapy science, validating effects in lab models, and combining a direct-to-consumer, subscription-driven model with Amazon and professional channels. Its goal is to expand internationally, develop new products, and advance clinical studies to further validate OS-01 and extend skin health.
About OneSkin
Industries
Biotechnology
Healthcare
Consumer Goods
Company Size
51-200
Company Stage
Series A
Total Funding
$40M
Headquarters
San Francisco, California
Founded
2016
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Simplify's Take
What believers are saying
- Strong DTC subscription model drives two-thirds of online sales, enhancing customer retention and revenue stability.
- OS-01 BODY and FACE trials confirm reduced inflammation, improved barrier function, and slowed biological aging over 12 weeks.
- Partnerships with Unilever Ventures and Selva Ventures validate science-backed model and support retail expansion by 2027.
What critics are saying
- L'Oréal and Estée Lauder will mass-market senolytic claims via AI discovery, undercutting OneSkin's premium pricing in 12–18 months.
- Reddit 'SCAM' allegations damage Gen X and millennial credibility in 3–6 months due to reliance on community validation.
- OS-01's 2.5-year age reduction claim relies on in-house 71-year skin models; independent replication failure triggers existential trust collapse in 6–12 months.
What makes OneSkin unique
- OS-01 is the first peptide clinically proven to reduce skin's biological age by targeting cellular senescence.
- OneSkin uniquely combines immunology, stem cell biology, and bioinformatics from four female Brazilian scientist founders.
- OS-01 delivers a 28% epidermal thickness increase and 2.5-year biological age reduction in five-day lab studies.
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Funding
Total Funding
$40M
Above
Industry Average
Funded Over
4 Rounds
Industry standards
Benefits
Health Insurance
Dental Insurance
Vision Insurance
Health Savings Account/Flexible Spending Account
401(k) Company Match
Remote Work Options
Home Office Stipend
Wellness Program
Growth & Insights
6 month growth
↑ 1%1 year growth
↑ 0%2 year growth
↑ 0%OneSkin is Hiring for 3 Jobs on Simplify!
Find jobs on Simplify and start your career today
About OneSkin
Industries
Biotechnology
Healthcare
Consumer Goods
Company Size
51-200
Company Stage
Series A
Total Funding
$40M
Headquarters
San Francisco, California
Founded
2016
OneSkin is Hiring for 3 Jobs on Simplify!
Find jobs on Simplify and start your career today