PBS Biotech

PBS Biotech

Single-use bioreactors for cell therapy

Overview

PBS Biotech designs, manufactures, and sells single-use bioreactor systems and offers process development and technical support for cell therapy manufacturing. Its core Vertical-Wheel technology provides gentle, homogeneous mixing suitable for shear-sensitive cells like iPSCs and MSCs, enabling scalable suspension or microcarrier culture from research to clinical production. The company operates a B2B model, supplying equipment and disposable components along with customized process development services to academic, biotech, and pharmaceutical customers. With an ISO 9001:2015 certified facility and plans to scale to over $100 million in annual revenue, PBS Biotech aims to expand manufacturing capacity to support commercialization of cell therapies.

About PBS Biotech

Simplify's Rating
Why PBS Biotech is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Robotics & Automation

Industrial & Manufacturing

Biotechnology

Healthcare

Company Size

51-200

Company Stage

Late Stage VC

Total Funding

$49M

Headquarters

Camarillo, California

Founded

2006

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Simplify's Take

What believers are saying

  • PBS raised $17 million on January 6, 2025, then expanded capacity for $100 million revenue.
  • December 2025 MiniPRO and 2026 denovoMATRIX collaboration strengthen early-stage and iPSC workflows.
  • July 21, 2026 award coverage boosted credibility during a crowded cell-therapy capital cycle.

What critics are saying

  • Thermo Fisher, Sartorius, and Cytiva can bundle bioreactors with broader consumables contracts.
  • Customer concentration remains opaque; losing one large cell-therapy program can crush recurring disposables revenue.
  • If commercialization stalls after MiniPRO, PBS becomes a niche equipment vendor with weak pricing power.

What makes PBS Biotech unique

  • Vertical-Wheel technology gentles shear-sensitive cells, especially iPSCs and MSCs, better than stirred tanks.
  • MiniPRO launched December 2025, enabling 24 parallel closed cultures for process development.
  • Martin Simonetti joined October 2025; Brian Lee remains CTO, preserving technical continuity.

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Funding

Total Funding

$49M

Above

Industry Average

Funded Over

3 Rounds

Late VC funding comparison data is currently unavailable. We're working to provide this information soon!
Late VC Funding Comparison
Coming Soon

Benefits

Flexible Work Hours

Growth & Insights and Company News

Headcount

6 month growth

-2%

1 year growth

-1%

2 year growth

4%
PR Newswire
Jul 21st, 2026
PBS Biotech wins 2026 cell Products Development of the Year award.

PBS Biotech wins 2026 cell Products Development of the Year award. Jul 21, 2026, 07:00 ET Recognition Highlights Company's Leadership in Advancing Linearly Scalable, Advanced Cell Therapy Manufacturing CAMARILLO, Calif., July 21, 2026 /PRNewswire/ - PBS Biotech, a leading developer of innovative single-use bioreactor technologies for cell therapy manufacturing, today announced it has been named Cell Therapy Products Development of the Year 2026 by Life Sciences Review. The company was also recognized among the publication's Top Companies in Cell and Gene Therapy, underscoring PBS Biotech's growing impact on the future of advanced therapeutic manufacturing. The recognition reflects PBS Biotech's continued commitment to helping cell therapy developers overcome one of the industry's greatest challenges: reliably scaling manufacturing while preserving cell quality and function. Through its patented Vertical-Wheel(R) bioreactor technology, PBS Biotech enables gentle, low-shear cell culture that supports the expansion and differentiation of a broad range of sensitive cell types, from early process development through commercial manufacturing. "As cell therapies continue to transform medicine, manufacturers need technologies that eliminate the traditional tradeoff between scalability and cell quality," said Martin Simonetti, Chief Executive Officer of PBS Biotech. "We're honored that Life Sciences Review has recognized our team's dedication to advancing manufacturing solutions that help bring life-changing therapies to patients faster." Unlike conventional stirred-tank bioreactors, PBS Biotech's Vertical-Wheel platform was specifically engineered to create homogeneous mixing with exceptionally low shear forces, providing an environment well suited for sensitive cell types including induced pluripotent stem cells (iPSCs), mesenchymal stem cells (MSCs), T cells, NK cells, CAR-T, CAR-NK, and pancreatic islet cells. The technology offers linear scalability from research through manufacturing, enabling customers to simplify process development and accelerate technology transfer. In its feature, Life Sciences Review highlighted PBS Biotech's customer-centric approach, commitment to innovation, and expanding collaborations across the cell and gene therapy ecosystem. The publication also recognized the company's role in helping developers address critical manufacturing bottlenecks as more cell therapies advance toward commercialization. "This recognition belongs to our employees, customers, collaborators, and partners who continue pushing the boundaries of regenerative medicine," Simonetti added. "Together, we're building the manufacturing foundation that will enable the next generation of cell therapies to reach more patients around the world." As demand for scalable, robust manufacturing platforms continues to grow, PBS Biotech remains focused on expanding its technology portfolio, supporting customer success, and advancing manufacturing solutions that accelerate the commercialization of transformative cell therapies. About PBS Biotech PBS Biotech is a biotechnology company dedicated to advancing the manufacture of next-generation cell therapies through innovative bioreactor technologies. Its patented Vertical-Wheel(R) bioreactor platform delivers gentle, low-shear mixing with scalable performance to support process development, clinical manufacturing, and commercial production. PBS Biotech partners with leading biotechnology companies, CDMOs, and academic institutions worldwide to accelerate the development and commercialization of life-changing cell therapies. About Forward-Looking Statements This press release contains forward-looking statements regarding PBS Biotech's future plans, expectations, and business outlook, including statements related to the development, adoption, and commercialization of cell therapy manufacturing technologies. These statements are based on current expectations and assumptions and are subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied. PBS Biotech undertakes no obligation to update any forward-looking statements as a result of new information, future events, or otherwise. Media Contact SOURCE PBS Biotech Inc.

FinSMEs
Jan 6th, 2025
PBS Biotech Raises $17M in Growth Funding

PBS Biotech raises $17M in Growth funding.

Pulse 2.0
Jan 6th, 2025
PBS Biotech Raises $17M for Growth

PBS Biotech raised $17 million in growth capital from Avego Management and BroadOak Capital Partners to enhance product innovation, process development, and quality systems. The company is expanding its ISO 9001:2015 manufacturing capacity to support over $100 million in annual revenue by mid-2025. PBS appointed Terrell Mathews as Chief Commercial Officer and Erik Wiberg as Chief Financial Officer to drive strategic growth and strengthen its market position in the cell therapy industry.

PR Newswire
Jan 6th, 2025
PBS Biotech Expands Leadership Team and Secures $17 Million in Growth Capital to Accelerate Delivery of Next Generation Cell and Regenerative Therapies

/PRNewswire/ -- PBS Biotech ("PBS"), a provider of innovative single-use bioreactor systems and bioprocess development services, has secured $17 million in...

PR Newswire
May 1st, 2024
Pbs Biotech Earns Iso 9001:2015 Certification, Demonstrating Commitment To Quality

CAMARILLO, Calif., May 1, 2024 /PRNewswire/ -- PBS Biotech, a leading provider of single-use bioreactor systems and process development services, announces the successful attainment of the ISO 9001:2015 certification of its Quality Management System (QMS). This certification reflects PBS Biotech's commitment to meet the needs of customers by maintaining effective quality standards across its operations. The ISO 9001:2015 certification will ensure that PBS Biotech's single-use bioreactor systems are manufactured and delivered under the highest standards of quality management, significantly enhancing their reliability, robustness, and efficacy for commercial manufacturing of cell therapy products."Earning this ISO 9001:2015 certificate is not only a recognition of the quality of our products but also of the way we operate on a daily basis," commented Brian Lee, Chief Executive Officer of PBS Biotech. "I feel proud of how our world-class team elevates the technology and standards for the emerging cell therapy industry."The ISO 9001:2015 certification is an internationally recognized standard for quality management systems. To achieve and maintain this certification, a company must demonstrate a robust system that is repeatable, measurable, and implements continuous improvement. This certification underscores PBS Biotech's ability to consistently provide products and services that fully meet customer needs as well as statutory and regulatory requirements.As part of the evaluation process, an independent auditor performed an on-site audit at PBS Biotech's Camarillo-based facilities over the course of 5 days

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