Pathos

Pathos

AI-powered platform for oncology drug development

Overview

Pathos combines artificial intelligence with oncology to speed up cancer drug development. It analyzes large oncology datasets, including genomics, using advanced AI and machine learning to identify novel therapeutic targets and biomarkers, guiding the creation of more effective, personalized cancer treatments. The company collaborates with pharmaceutical and biotechnology partners to de-risk pipelines, shorten development timelines, and increase the odds of success for new cancer therapies. Pathos differentiates itself by offering an integrated data-driven platform that leverages diverse genomic and clinical data to drive target validation and biomarker discovery for partner programs. Its goal is to accelerate the delivery of better cancer treatments by turning complex data into actionable insights.

Significant Headcount Growth

About Pathos

Simplify's Rating
Why Pathos is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & Analytics

AI & Machine Learning

Biotechnology

Healthcare

Company Size

51-200

Company Stage

Series D

Total Funding

$365M

Headquarters

Chicago, Illinois

Founded

2022

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Simplify's Take

What believers are saying

  • $365M Series D funding in 2026 values Pathos at $1.6B to expand AI oncology platform.
  • AstraZeneca $200M partnership with Tempus validates PathOS for multimodal oncology model development.
  • Q1 2026 acquisition of DeuterOncology stake creates portfolio returns beyond licensing fees.

What critics are saying

  • Pathios Therapeutics' PTT-4256 GPR65 inhibitor captures immunotherapy market share within 12-24 months.
  • AstraZeneca diverts resources to Tempus-led model, sidelining PathOS within 6-12 months.
  • Pocenbrodib trial underperforms versus abiraterone/olaparib by Q2 2026, exhausting cash reserves.

What makes Pathos unique

  • Pathos AI's PathOS platform integrates multiomic data for biomarker-driven patient selection in mCRPC trials.
  • Foundry platform identified DO-2 MET inhibitor with 100% tumor shrinkage and 5% edema in Phase 1 NSCLC.
  • Pocenbrodib targets novel CBP/p300 proteins to overcome resistance in post-anti-androgen mCRPC patients.

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Funding

Total Funding

$365M

Above

Industry Average

Funded Over

3 Rounds

Series D funding is typically for companies that are already well-established but need more funding to continue their growth. This round is often used to stabilize the company or prepare for an IPO.
Series D Funding Comparison
Above Average

Industry standards

$77M
$70M
Twilio
$80M
Handshake
$100M
Affirm
$283M
Pathos

Benefits

Hybrid Work Options

Remote Work Options

401(k) Retirement Plan

401(k) Company Match

Health Insurance

Dental Insurance

Vision Insurance

Paid Vacation

Paid Holidays

Wellness Program

Mental Health Support

Conference Attendance Budget

Professional Development Budget

Stock Options

Growth & Insights and Company News

Headcount

6 month growth

-1%

1 year growth

4%

2 year growth

4%
GlobalData
May 16th, 2025
Pathos AI raises $365m for oncology drug development

Pathos AI has raised $365m in a Series D funding round as it prepares to widen its AI-enabled platform to advance the development of oncology drugs.

The Pharma Letter
May 16th, 2025
Pathos AI lands $365 million for AI-driven cancer drugs

Pathos AI, a US biotech specializing in artificial intelligence for cancer drug development, has raised $365 million in a series D financing round, lifting its valuation to about $1.6 billion.

The Manila Times
May 8th, 2025
Pathos AI Appoints Iker Huerga as Chief Executive Officer to Lead the Next Era of AI-Enabled Drug Development

NEW YORK, May 08, 2025 (GLOBE NEWSWIRE) - Pathos AI, a leading AI-enabled biotech company focused on transforming drug development in oncology, today announced the appointment of Iker Huerga as Chief Executive Officer and Board Member.

Pharmaceutical Business Review
Apr 25th, 2025
Tempus AI, AstraZeneca, and Pathos AI join forces on cancer care

Tempus AI has entered into strategic partnerships with AstraZeneca and Pathos AI to develop a multimodal foundation model in oncology.

GlobalData
Apr 24th, 2025
AstraZeneca enters $200m AI cancer pact with Tempus and Pathos

AstraZeneca, Tempus and Pathos AI have signed a multi-year agreement to develop a large-scale multimodal deep learning model designed to accelerate cancer drug discovery.

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