Pearl

Pearl

AI-powered dental fraud detection and restoration

Overview

Pearl provides AI-powered solutions for the dental industry, serving dentists, dental labs, and insurance carriers. Its products include Pearl Protect, which uses machine learning to detect fraud, waste, and abuse in dental insurance claims; Smart Margin, which uses computer vision to mark margins in 3D intraoral scans to speed up restoration fabrication; and Prep Assess, which provides real-time evaluation of prepared teeth to ensure a proper restoration fit. The company licenses software and charges service fees, earning revenue from licensing and support/services. Pearl distinguishes itself through patented AI and deep expertise in both dentistry and AI, offering integrated tools across claims analysis, imaging, and clinical assessment. The goal is to improve efficiency, accuracy, and outcomes in dental care and insurance by reducing fraud and streamlining restoration workflows.

About Pearl

Simplify's Rating
Why Pearl is rated
B-
Rated B on Competitive Edge
Rated A on Growth Potential
Rated D+ on Differentiation

Industries

Data & Analytics

Enterprise Software

AI & Machine Learning

Healthcare

Company Size

201-500

Company Stage

Series B

Total Funding

$69M

Headquarters

West Hollywood, California

Founded

2019

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Simplify's Take

What believers are saying

  • Smile Brands began rolling Pearl across 600 locations in June 2026.
  • PDS Health selected Pearl for 1,100 practices on February 3, 2026.
  • ClearDent integrated Pearl into Canadian workflows in June 2026, expanding international distribution.

What critics are saying

  • DSOs can standardize on Henry Schein or other vendors and squeeze Pearl out by 2027.
  • Pearl RCM invites payer audits, claim denials, and False Claims Act scrutiny starting 2026.
  • FDA, state boards, or class actions can suspend Pearl’s diagnostic approvals, ending enterprise adoption.

What makes Pearl unique

  • Pearl’s FDA-cleared dental X-ray AI works inside Dentrix Ascend and DSO workflows.
  • Pearl RCM fuses imaging, documentation, and claims in one dental revenue system.
  • Pearl’s June 2026 oral-health index analyzed 26 million x-rays across 15 million patients.

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Funding

Total Funding

$69M

Above

Industry Average

Funded Over

2 Rounds

Notable Investors:
Series B funding is typically for startups that have proven their business model and need more funding to expand rapidly—often by entering new markets or adding more products. Investors are usually venture capital firms that specialize in later-stage investments.
Series B Funding Comparison
Above Average

Industry standards

$35M
$45M
Linktree
$58M
Pearl
$65M
Substack
$100M
ClickUp

Benefits

Competitive Benefit and Compensation Offerings

Ongoing Training and Development Opportunities

Unlimited Paid Time Off

Remote Work Options

Growth & Insights and Company News

Headcount

6 month growth

-2%

1 year growth

-3%

2 year growth

7%
National Data Solutions
Jul 12th, 2026
Pearl launches ai-powered dental RCM platform.

Pearl launches ai-powered dental RCM platform. July 12, 2026 · For Dental Practice Owners and CFOs Struggling with insurance-related issues and low reimbursement rates? You're not alone. Many dental practices still face complicated workflows and delays due to the fragmented patient claim process. Instead of chasing denials after they happen, let Nationaldatasolutions help you reduce them upstream. Focus on prevention instead. #DenialPrevention #HealthcareRevenue #DentalConsulting #PracticeManagement Ready to transform your dental data? Book a 30-minute strategy call with the NDS team.

Business Wire
Jun 18th, 2026
Pearl and ClearDent partner to bring AI disease detection to Canadian dental practices

Pearl, a dental AI solutions provider, has partnered with ClearDent to integrate its Second Opinion radiologic disease detection software into ClearDent's practice management platform across Canada. The API-based integration will enable Canadian dentists to access AI-assisted pathology detection for conditions including caries, calculus and periapical radiolucency directly within their existing clinical workflow. Pearl's Second Opinion software has received regulatory clearance in 120 countries, including Canada, the US, Australia, New Zealand and Europe. The partnership will provide Canadian dental practices with AI-powered tools to enhance diagnostic accuracy and standardise patient care. Founded in 2019, Pearl introduced the first FDA-cleared AI for identifying diseases in dental X-rays. ClearDent has served Canadian dental practices since 2002 with its unified practice management platform.

Dentistry Today
Jun 15th, 2026
Smile Brands selects Pearl as AI partner.

Smile Brands selects Pearl as AI partner. * June 15, 2026 * 3 minutes read * 2 hours ago Pearl's dental AI platform helps Smile Brands scale diagnostic clarity and clinical consistency, leading to improved patient trust. Pearl, the global leader in dental AI solutions, today announced that Smile Brands, one of the nation's leading providers of business support services to dental groups across the U.S., has selected Pearl as its dental AI partner. Smile Brands' selection of Pearl followed a rigorous, multi-vendor evaluation process, where Pearl demonstrated leading clinical performance and a unique ability to integrate seamlessly into existing care delivery workflows. Smile Brands and Pearl have completed an initial pilot of Radiographic AI with promising results. During the pilot, Smile Brands observed measurable improvements in how clinicians presented diagnoses, which led to an increase in same-day treatment acceptance, an outcome closely tied to patient understanding and trust. The companies have begun rolling out the product to a significant number of offices across the system, with the goal of full deployment in the coming months. In large-scale dental organizations, the challenge is no longer access to data. It is consistency in how that data is interpreted and acted upon. Pearl addresses this gap by embedding AI directly into the clinical workflow, helping standardize how radiographs are read, understood, and communicated across every location, while also creating a foundation for broader clinical and operational intelligence across the practice. At the point of care, Pearl brings real-time radiologic analysis into the imaging workflow, automatically identifying potential pathologies on dental radiographs and presenting them with clear, visual evidence during diagnosis. By making findings more visible, clinicians are better equipped to engage patients before conditions progress. More transparent diagnostic processes help clinicians communicate findings with confidence and enable patients to better understand and move forward with recommended treatment. Beyond diagnosis, Pearl's platform extends that same layer of intelligence across the broader dental workflow, supporting clinical calibration, surfacing trends in treatment planning, and enabling more consistent decision-making across providers, locations, and time. By connecting insight at the chairside to system-level visibility, Smile Brands can continuously improve how care is delivered across its network, reinforcing a more proactive, prevention-oriented approach to dentistry. This system-level visibility is increasingly critical for organizations like Smile Brands that are working to reduce variability in care while preserving clinician autonomy, a balance that sits at the heart of modern dental support organizations. "What really set Pearl apart for us was their partner-first approach, their forward-thinking vision for technology, and how easy the platform was to use," said Steve Bilt, CEO of Smile Brands. "Together, we're creating new opportunities for our providers to learn from each other, collaborate more closely with patients, and ultimately deliver an even higher standard of care." "At Smile Brands, they're not just scaling operations, but also scaling a standard of care," said Ophir Tanz, Founder and CEO of Pearl. "That requires infrastructure that ensures every clinician has the same level of diagnostic clarity and every patient receives the same level of understanding. With Pearl, that foundation begins with radiologic insight and extends across the workflows that turn diagnosis into action, helping enable earlier intervention and better long-term outcomes. We're proud to partner with Smile Brands to help deliver consistent, high-quality care across every location they serve." About Pearl Pearl is a dental AI company committed to enhancing how patient care is delivered. Founded in 2019 by a team with decades of experience developing successful, enterprise-grade computer vision solutions, Pearl introduced the first-ever FDA-cleared AI capable of reading and instantly identifying diseases in dental X-rays. With regulatory clearance in 120 countries, Pearl's AI assists dentists in making precise clinical decisions and effectively communicating with patients, thereby transforming the dental care experience worldwide. As dentistry's global AI leader, Pearl is committed to the ongoing innovation of robust, accessible AI tools that improve patient health outcomes and build greater trust in dental medicine. To request a demo, please visit hellopearl.com/demo. About Smile Brands Smile Brands, based in Costa Mesa, California, is one of the largest providers of dental support services in the United States. Smile Brands supports a portfolio of 600 locations with over 80 brands, including well-known regional brands: Bright Now! Dental, Castle Dental, Merit Dental, Midwest Dental, Monarch Dental, and Mondovi Dental. The company provides comprehensive business services through exclusive long-term agreements with affiliate dental groups, allowing affiliated practices to spend more time caring for patients and less time on the administrative, marketing, and financial aspects of operating a dental office. The organization receives frequent recognition for its award-winning culture and has been recognized as a "Best Place to Work" by Glassdoor, Comparably, Stevie(R) Awards, and more.

Associated Press
Jun 15th, 2026
Smile Brands deploys Pearl's dental AI across 600 US locations to improve diagnosis consistency

Smile Brands, one of the largest US dental support service providers, has selected Pearl as its dental AI partner following a multi-vendor evaluation process. The company is rolling out Pearl's Radiographic AI across its network of 600 locations after a successful pilot showed improvements in diagnosis presentation and same-day treatment acceptance. Pearl's platform provides real-time radiologic analysis, automatically identifying potential pathologies on dental X-rays and presenting visual evidence during diagnosis. The system aims to standardise how radiographs are interpreted across locations whilst supporting clinical calibration and treatment planning consistency. Founded in 2019, Pearl developed the first FDA-cleared AI for reading dental X-rays and holds regulatory clearance in 120 countries. Smile Brands expects full deployment across its network within coming months.

Pearl Health
Apr 30th, 2026
Pearl brings Dental AI natively into Dentrix Ascend.

Pearl brings Dental AI natively into Dentrix Ascend. Integration delivers Pearl's best-in-class diagnostic AI directly inside Henry Schein One's cloud-based dental technology platform, eliminating workflow friction and workarounds. April 30, 2026 LOS ANGELES - Pearl, the global leader in dental AI solutions, today announced a native integration with Dentrix Ascend, the cloud-based dental technology platform from Henry Schein One. Pearl surfaces real-time pathology findings as x-rays are captured, without clinicians ever leaving the Dentrix Ascend platform. "This integration puts Pearl directly into the workflows practices already rely on, working in real time to reduce friction, eliminate guesswork, and free dentists to focus on patient care." Dental AI at the point of care has long been held back by fragmented workflows. Switching between platforms, importing images manually, and reconciling findings across systems adds friction that slows clinical teams and dilutes the value of AI. Native integration entirely eliminates that friction. "The best AI in dentistry should take work off the clinician - not add to it," said Ophir Tanz, Founder and CEO of Pearl. "This integration puts Pearl directly into the workflows practices already rely on, working in real time to reduce friction, eliminate guesswork, and free dentists to focus on patient care." For clinical teams, the experience is seamless. As radiographs are captured in Dentrix Ascend, Pearl identifies and displays findings including decay, bone loss, root absences, calculus, and other pathologies within the Dentrix Ascend interface. No separate login. No parallel window. No manual export. The integration puts AI at the point of care, surfacing findings that support clinician judgment. "This integration reflects a shift toward an open dental technology ecosystem where clinicians can choose the tools that serve them best, and where workflows ensure streamlined dental AI access at the point of care, " noted Erica Zerante, VP of Partnerships at Pearl. Pearl has deployed AI across radiographic analysis, clinical documentation, and revenue cycle workflows, giving practices integrated AI infrastructure that connects diagnosis to downstream operations. The Dentrix Ascend integration extends that infrastructure to one of dentistry's most popular cloud dental technology platforms, making high-performance AI accessible to a significant new segment of the market. The integration will be available for all Dentrix Ascend users in the coming weeks. Practices can learn more and activate Pearl's integration through their Dentrix Ascend account or by visiting hellopearl.com/demo.

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