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ProBio

Biologics and CGT CDMO platform

Overview

ProBio (GenScript ProBio) is a biologics and cell/gene therapy CDMO platform that offers end-to-end services from antibody and protein discovery through commercial manufacturing, plus plasmid, viral vector, and mRNA CMC services. It operates GMP-capable facilities in China and the United States and has supported 100+ IND filings for global clients since 2017. The company, spun from GenScript, provides a full suite of development and manufacturing options, enabling clients to move products from discovery to market readiness. Unlike many single-solution providers, ProBio covers the entire spectrum of biologics and CGT workflows in-house, with multi-region GMP capacity and a track record of regulatory support. Its goal is to help customers bring biologics and gene-therapy products to clinical trials and commercial production by offering integrated, globally accessible CDMO services.

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About ProBio

Simplify's Rating
Why ProBio is rated
B+
Rated B on Competitive Edge
Rated A on Growth Potential
Rated B on Differentiation

Industries

BiotechnologyHealthcare

Company Size

N/A

Company Stage

N/A

Total Funding

N/A

Headquarters

Nanjing City, China

Founded

2017

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Simplify's take

What believers are saying

  • May 11, 2026: Curocell's Korean CAR-T approval validated ProBio's LVV manufacturing and change-control execution.
  • May 2026: Hopewell AAV services and packaging tests broadened U.S. customer conversion from research to GMP.
  • Nov. 2026: AbTis deal creates royalty upside plus validation for ProBio's biologics discovery engine.

What critics are saying

  • Nov. 13, 2026: GenScript plans a ProBio spin-off, keeping control and consolidating results.
  • AbTis kept undisclosed economics on Nov. 10, 2026, limiting proof of asset value.
  • End-to-end CDMO rivals like Lonza and WuXi pressure pricing; differentiated margins can erode quickly.

What makes ProBio unique

  • Nov. 8, 2026: China's only GMP platform with IVT linearized plasmids and viral vectors separately.
  • May 2026: Hopewell launched viral-vector packaging tests using same CMC plasmids and cell lines.
  • ProBio paired discovery-to-manufacturing with AbTis licensing on Nov. 10, 2026.

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Benefits

  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • 401(k) Retirement Plan
  • 401(k) Company Match
  • Parental Leave
  • Paid Vacation
  • Paid Sick Leave
  • Paid Holidays
  • Health Savings Account/Flexible Spending Account
  • Life Insurance
  • Disability Insurance

Company News

Pharmaceutical Technology
Nov 11th, 2026
ProBio signs global antibody licensing deal with AbTis.

ProBio signs global antibody licensing deal with AbTis. The asset was developed via ProBio's biologics discovery and development operations and is directed against an oncology target. ProBio has entered into an exclusive worldwide licensing agreement with South Korean biotechnology firm AbTis to develop and commercialise an early-stage therapeutic antibody asset. The asset was developed via ProBio's biologics discovery and development operations and is directed against an oncology target. ProBio is set to receive an upfront payment, alongside eligibility for potential payments tied to developmental and commercial milestones. Financial figures of the deal were not disclosed. The agreement additionally entitles the company to receive royalties on future product sales generated by the candidate. AbTis, a subsidiary of Dong-A ST, plans to incorporate the licensed antibody into its portfolio of bispecific antibody-drug conjugates (ADCs). The company will apply its AbClick site-specific conjugation technology to develop the candidate into a next-generation ADC. The AbClick linker platform enables controlled, site-specific antibody conjugation, designed to progress conjugate consistency and characteristics relative to conventional non-specific conjugation methods across oncology applications. ProBio CEO Allen Guo said: "This agreement demonstrates the value of ProBio's strategy to not only support its partners' programmes, but also generate differentiated assets that can advance into innovative therapeutic development. "By combining ProBio's biologics discovery capabilities with AbTis' site-specific ADC technology, we have the opportunity to accelerate the development of a promising oncology asset and create additional value for patients and our partners." The transaction aligns with ProBio's role as a global contract research, development, and manufacturing organisation (CRDMO), providing partners with an integrated pathway that links scientific research directly with manufacturing capabilities. Operating across biologics, cell therapy, and gene therapy, ProBio maintains scalable, good manufacturing practice (GMP)-compliant facilities designed to de-risk development schedules and shorten production timelines. AbTis remains focused on advancing bioconjugate therapeutics, seeking to improve clinical outcomes for individuals treated for cancer and other serious diseases. Give your business an edge with its leading industry insights.

Sing Tao News Corporation Limited
Sep 2nd, 2026
Genscript shares slump 12pc on proposed spinoff of Probio Technology.

Genscript shares slump 12pc on proposed spinoff of Probio Technology. 4 hours ago GenScript Biotech Corporation. GenScript Biotech Corporation (1548) saw its shares plunge nearly 12 percent in early trading on Friday after announcing a proposed spin-off and separate listing of its subsidiary Probio Technology on the main borad. The arm operates Genscript's biologics and advanced therapy contract research, development, and manufacturing organization services, according to an exchange filing. The company said it submitted an application to the Stock Exchange on August 14, while details of the proposed spin-off have yet to be finalized After the proposed spin-off is completed, the biotech firm noted that it will continue to hold a controlling interest in ProBio, which will remain a subsidiary of the company, and its financial results will continue to be consolidated into the group's financial statements.

PR Newswire
Jul 1st, 2026
ProBio's AAV manufacturing powers UC Irvine and GlyTR's $30M pan-cancer CAR-T programme

UC Irvine School of Medicine and GlyTR Therapeutics have developed a next-generation CAR T-cell platform targeting tumour-associated carbohydrate antigens across multiple cancers. The therapy uses a lectin binding mechanism to eliminate cancer cells whilst minimising toxicity in solid tumours. Contract manufacturer ProBio delivered GMP AAV6 material that achieved 80% CAR gene insertion efficiency, doubling previous research-grade results. The improved material produced highly potent CAR T cells that successfully cleared tumours in mice. The patented technology, licensed to GlyTR Therapeutics and recently reported in Cell, has secured approximately $30 million in total funding, including a $4.6 million grant from the California Institute for Regenerative Medicine. The team is now preparing for IND submission and clinical trials at UC Irvine's Chao Family Comprehensive Cancer Center.

PR Newswire
May 11th, 2026
ProBio and Curocell win regulatory approval for Korean CAR-T therapy with 82% response rate

ProBio and Curocell have achieved regulatory approval for Anbalcabtagene autoleucel (Anbal-cel), a next-generation CD19-targeted CAR-T cell therapy for relapsed or refractory diffuse large B-cell lymphoma. The therapy demonstrated an 82% overall response rate and 82% complete response rate in Phase 1/2 studies. The treatment utilises Curocell's proprietary OVIS platform, which suppresses PD-1 and TIGIT immune checkpoint receptors to enhance efficacy within the tumour microenvironment. ProBio supported the programme from post-IND supplier change through to commercial production, completing process characterisation in four months and securing Korea's first GMP approval for a lentiviral vector manufacturing facility. The approval marks Korea's first commercialised CAR-T therapy. Both companies plan to expand into global markets whilst developing additional advanced therapeutics.

PR Newswire
May 4th, 2026
ProBio launches viral vector packaging test to de-risk cell and gene therapy development

ProBio Inc. has launched its Viral Vector Packaging Test to accelerate decision-making in cell and gene therapy development. The service supports multiple viral vector modalities, including lentiviral vectors for CAR-T applications and AAV for gene therapy, with turnaround times of three to five weeks. The test enables rapid comparative evaluation of packaging strategies during early development, using the same cell lines and packaging plasmids applied in later-stage manufacturing. It includes comprehensive quality assessments covering physical titer, genome purity, endotoxin levels and full/empty ratio. The offering is designed for candidate selection, feasibility assessment and sample generation for pharmacology studies. It builds on ProBio's 2025 viral vector facility opening, strengthening the company's end-to-end capabilities in advanced therapies.

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