Profound Research

Profound Research

Clinical trial site network for community physicians

Overview

Profound Research is a clinical research organization that operates a nationwide network of trial sites, partnering with community physicians to bring pharmaceutical and biotech studies into everyday medical practices. It recruits and enrolls patients from a combined database of more than 1.25 million people, coordinates site operations and investigator oversight, and runs studies across more than 15 therapeutic areas on behalf of trial sponsors. Its network spans 22 sites across four geographies, with over 1,000 providers, 110-plus active investigators, and more than 130 clinical trials conducted to date. What sets Profound Research apart is its model of embedding research infrastructure within existing community practices, giving physicians and their patients access to experimental treatments without leaving their local care setting. The goal is to expand patient access to new treatments while helping sponsors conduct trials through a community-based site network.

About Profound Research

Simplify's Rating
Why Profound Research is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Company Size

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Company Stage

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Total Funding

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Headquarters

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Founded

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Simplify's Take

What believers are saying

  • Profound raised a $96 million Series C at a $1 billion valuation in February 2026.
  • March 2026 San Diego Sports Medicine partnership expands internal medicine and metabolic trial access.
  • The company reports 130-plus completed trials and active studies across four geographies.

What critics are saying

  • Profound’s 2026 growth depends on continued capital after raising $96 million in February 2026.
  • Big-site networks and hospital systems can copy its embedded-site model and squeeze margins.
  • If trial enrollment slows, contract wins and investigator relationships can unravel quickly.

What makes Profound Research unique

  • Profound embeds research into community physician practices across 22 sites and 110 investigators.
  • Its network claims 1.25 million patients, giving unusual local recruitment depth.
  • The MHP Detroit center of excellence expands access through multi-specialty community infrastructure.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

Health Savings Account/Flexible Spending Account

Unlimited Paid Time Off

Flexible Work Hours

Remote Work Options

Paid Vacation

Paid Sick Leave

Paid Holidays

Sabbatical Leave

Hybrid Work Options

Stock Options

Company Equity

401(k) Retirement Plan

Wellness Program

Mental Health Support

Gym Membership

Phone/Internet Stipend

Home Office Stipend

Professional Development Budget

Conference Attendance Budget

Training Programs

Tuition Reimbursement

Student Loan Assistance

Parental Leave

Family Planning Benefits

Fertility Treatment Support

Adoption Assistance

Childcare Support

Elder Care Support

Relocation Assistance

Employee Referral Bonus

Meal Benefits

Legal Services

Employee Discounts

Company Social Events

Company News

PR Newswire
Nov 20th, 2023
Profound Research And Michigan Health Professionals Announce Clinical Research Partnership And Center Of Excellence In Detroit

MHP is a leading provider of healthcare in the Detroit area, and we share a vision of bringing innovative medicines to support the improvement of patients' lives in the community. .

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