Prolific Machines

Prolific Machines

Develops cost-efficient cultured meat production

Overview

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About Prolific Machines

Simplify's Rating
Why Prolific Machines is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Food & Agriculture

Industrial & Manufacturing

Biotechnology

Company Size

51-200

Company Stage

Series B

Total Funding

$97M

Headquarters

Emeryville, California

Founded

2020

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Simplify's Take

What believers are saying

  • July 2026 Gates Foundation grant funds affordable monoclonal antibodies for low-income countries.
  • 2026 site lists services for biotechs, CDMOs, and licensing, broadening revenue paths.
  • May 2025 FDA program status improves credibility with regulators and pharma partners.

What critics are saying

  • The company pivoted from cultured meat toward biopharma, confusing employer branding and hiring.
  • No 2026 customer revenues are public, so commercialization still depends on partner conversions.
  • If biomanufacturing deals stall, Prolific risks becoming a funded platform without durable demand.

What makes Prolific Machines unique

  • 2026 website says Prolific integrates optogenetic cell lines, illumination, AI optimization.
  • May 2025 FDA Emerging Technology Program entry validates its industrial biomanufacturing platform.
  • June 2024 Series B1 drew Fonterra, Breakthrough Energy Ventures, and In-Q-Tel.

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Funding

Total Funding

$97M

Above

Industry Average

Funded Over

3 Rounds

Series B funding is typically for startups that have proven their business model and need more funding to expand rapidly—often by entering new markets or adding more products. Investors are usually venture capital firms that specialize in later-stage investments.
Series B Funding Comparison
Above Average

Industry standards

$35M
$45M
Linktree
$55M
Prolific Machines
$65M
Substack
$100M
ClickUp

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

Hybrid Work Options

Company Equity

Mental Health Support

Paid Vacation

Meal Benefits

Company Social Events

Growth & Insights and Company News

Headcount

6 month growth

1%

1 year growth

-2%

2 year growth

0%
Business Wire
Feb 13th, 2025
Prolific Machines Announces the Appointment of Former Forge Biologics Executive, Christina Perry, as CFO Setting the Stage for Optogenetics Leader's Biopharmaceutical Commercial Ramp Up

Christina Perry, MSA, CPA, former Chief Financial Officer (CFO) of Forge Biologics, recently acquired by Ajinomoto Co., has been appointed as CFO of Prolific Machines to support the company's meteoric growth as it works towards building a resilient, sustainable business.

Business Wire
Aug 16th, 2024
Prolific Machines Receives Grant to Develop a Platform to Produce Affordable Monoclonal Antibodies to Prevent Infectious Disease in Low- and Middle-Income Countries

Prolific Machines receives Bill & Melinda Gates Foundation grant to leverage optogenetics expertise to develop more affordable monoclonal antibodies.

Webrazzi
Jun 7th, 2024
Prolific Machines raises $55M for light-based protein

Biotechnology startup Prolific Machines, which uses a photomolecular platform to create new proteins at low costs, has raised $55 million in a Series B1 round led by Fonterra's VC arm, The Ki Tua Fund. Other investors include Breakthrough Energy Ventures, Mayfield, SOSV, Shorewind Capital, Darco Capital, Conti Ventures, and In-Q-Tel (IQT). The funding will be used to commercialize their platform through industry partnerships.

AgFunder
Jun 6th, 2024
Optogenetics startup Prolific Machines raises $55m series B1, uses light to 'control virtually any cell function in any cell type'

Prolific Machines harnesses light-sensitive proteins to control cells used in biomanufacturing using optogenetics.

The Business Journals
Jun 6th, 2024
Prolific Machines raises $55 million to harness light on a cellular level

Prolific Machines announced on Thursday that it raised $55 million in a Series B round led by the Ki Tua Fund, the corporate venture capital division of New Zealand-based dairy giant Fonterra Co-operative Group.

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