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Quantum-Si provides proteomics tools that analyze proteins at the single-molecule level using NGPS on a semiconductor chip. The workflow immobilizes peptides on a chip, uses fluorescent recognizers to read amino acids as they are cleaved, and delivers data through an end-to-end platform of benchtop instruments, consumables, and cloud software. It differentiates itself by combining semiconductor-based single-molecule proteomics with an integrated, easy-to-use platform and flexible financing that converts capital expenditures to operating expenses. Its goal is to speed up drug discovery and clinical diagnostics by enabling detailed profiling of proteoforms and post-translational modifications across research, pharma, and diagnostics labs.
Industries
Data & Analytics
Biotechnology
Healthcare
Company Size
51-200
Company Stage
IPO
Headquarters
Guilford, Connecticut
Founded
2013
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Total Funding
$640M
Above
Industry Average
Funded Over
4 Rounds
Health Insurance
401(k) Retirement Plan
401(k) Company Match
Real-time performance monitoring
Remote Work Options
Paid Vacation
Paid Holidays
Hybrid Work Options
Wellness Program
Mental Health Support
Gym Membership
Phone/Internet Stipend
Home Office Stipend
Quantum-Si has delayed the launch of its Proteus protein sequencing platform to the second quarter of 2027 from the end of 2026, citing the need for an additional integrated instrument design cycle before production. The company is also cutting its workforce by approximately 20% to reduce cash burn and fund the revised development timeline. Chief Executive Officer Jeff Hawkins said the delay stems from an internal review of instrument performance, manufacturing processes, and supply-chain readiness. Testing of integrated units during the first half of 2026 revealed variability in performance across systems. Some instruments performed above internal specifications, while others met or fell slightly below targets. The additional design cycle will focus on improving repeatability across systems and making manufacturing changes to simplify production and improve yields.
Quantum-Si has delayed the commercial launch of its Proteus protein sequencing platform to Q2 2027 and implemented a 20% workforce reduction to extend its cash runway into Q4 2028. The proteomics technology company reported second quarter revenue of $344,000, down from $591,000 in the prior year period. The company posted a net loss of $23.5 million for the quarter, compared to $28.8 million a year earlier. The launch delay incorporates an additional design cycle focused on manufacturing readiness and system repeatability. Chief executive Jeff Hawkins said testing has reinforced confidence in the technology, whilst the extra cycle will strengthen commercialisation readiness. Quantum-Si highlighted a $4 billion annual market opportunity in non-human proteomics, identified through work on agricultural applications and pathogen detection. The workforce reduction is expected to generate approximately $12 million in annualised savings whilst maintaining critical development resources.
Quantum-Si reported first-quarter 2026 revenue of $258,000 and said the year would focus on development and market preparation for its next-generation Proteus protein sequencing platform, which is expected to launch commercially by year-end. The company completed sequencing on fully integrated Proteus instruments during the quarter, a milestone CEO Jeff Hawkins described as a significant de-risking event. Quantum-Si increased detectable amino acids from 15 to 17 within four months and aims to detect 18 amino acids at launch and all 20 during 2026. Proteus is expected to offer advantages over the current Platinum system, including automation, higher throughput and longer peptide read lengths. The company is also developing post-translational modification analysis capabilities for the platform.
Quantum-Si, a proteomics technology company, reported first quarter 2026 revenue of $258,000 and a net loss of $21.7 million. The company announced successful sequencing on integrated Proteus instruments and sequenced its first customer samples on a prototype system, with its developmental kit now detecting 17 amino acids. Chief executive Jeff Hawkins said the company achieved automated sequencing runs on integrated Proteus instruments, bringing together instrumentation, KinetIQ Array, sequencing chemistry and data analysis. The company plans early access sites for Proteus instruments this summer ahead of commercial launch at year-end 2026. Quantum-Si held $190.4 million in cash and marketable securities as of 31 March, expected to fund operations into second quarter 2028. The company reiterated 2026 guidance of approximately $1.0 million revenue and adjusted operating expenses of $98.0 million or less.
Quantum-Si, a proteomics technology company, reported first quarter 2026 revenue of $258,000 and announced significant progress on its Proteus protein sequencing platform. The company achieved automated sequencing runs on integrated Proteus instruments and sequenced its first customer samples on prototype systems. The company's developmental sequencing kit currently detects 17 amino acids. Quantum-Si plans to launch Proteus commercially by the end of 2026, with early access sites receiving instruments this summer. First quarter net loss was $21.7 million, compared to $19.2 million in the prior year. Operating expenses decreased to $24.1 million from $25.6 million. The company held $190.4 million in cash and marketable securities as of 31 March, expected to fund operations into the second quarter of 2028. Quantum-Si reiterated 2026 guidance of approximately $1 million revenue and $98 million or less in adjusted operating expenses.
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Industries
Data & Analytics
Biotechnology
Healthcare
Company Size
51-200
Company Stage
IPO
Headquarters
Guilford, Connecticut
Founded
2013
Find jobs on Simplify and start your career today