Quantum-Si

Quantum-Si

Proteomics instrument platform for NGPS sequencing

Overview

Quantum-Si provides proteomics tools that analyze proteins at the single-molecule level using NGPS on a semiconductor chip. The workflow immobilizes peptides on a chip, uses fluorescent recognizers to read amino acids as they are cleaved, and delivers data through an end-to-end platform of benchtop instruments, consumables, and cloud software. It differentiates itself by combining semiconductor-based single-molecule proteomics with an integrated, easy-to-use platform and flexible financing that converts capital expenditures to operating expenses. Its goal is to speed up drug discovery and clinical diagnostics by enabling detailed profiling of proteoforms and post-translational modifications across research, pharma, and diagnostics labs.

About Quantum-Si

Simplify's Rating
Why Quantum-Si is rated
C+
Rated B on Competitive Edge
Rated C on Growth Potential
Rated C on Differentiation

Industries

Data & Analytics

Biotechnology

Healthcare

Company Size

51-200

Company Stage

IPO

Headquarters

Guilford, Connecticut

Founded

2013

Get referred to Quantum-Si

See people who can refer or advise you

Simplify Jobs

Simplify's Take

What believers are saying

  • Quantum-Si sequenced first customer samples on Proteus prototype systems in Q1 2026.
  • Management says 17 amino acids are detectable now and all 20 should arrive during 2026.
  • Cash of $169.9 million funds operations into Q4 2028 after 20% headcount cuts.

What critics are saying

  • Proteus slipped to Q2 2027 after another design cycle, signaling execution risk.
  • Quantum-Si's Q2 2026 revenue was $344,000, and first-half sales fell 57%.
  • Nasdaq notified QSI on July 23, 2026 that it failed the $1.00 bid-price rule.

What makes Quantum-Si unique

  • Jonathan Rothberg built Quantum-Si around benchtop proteomics, not mass spectrometry.
  • Proteus targets single-molecule protein sequencing on semiconductor chips with amino-acid level readouts.
  • V4 chemistry and Platinum Pro extend coverage through glycine, methionine, and proline-rich peptides.

Help us improve and share your feedback! Did you find this helpful?

Funding

Total Funding

$640M

Above

Industry Average

Funded Over

4 Rounds

Post IPO Equity funding comparison data is currently unavailable. We're working to provide this information soon!
Post IPO Equity Funding Comparison
Coming Soon

Benefits

Health Insurance

401(k) Retirement Plan

401(k) Company Match

Real-time performance monitoring

Remote Work Options

Paid Vacation

Paid Holidays

Hybrid Work Options

Wellness Program

Mental Health Support

Gym Membership

Phone/Internet Stipend

Home Office Stipend

Stock Price

Growth & Insights and Company News

Headcount

6 month growth

1%

1 year growth

0%

2 year growth

2%
Yahoo Finance
Aug 14th, 2026
Quantum-Si delays protein sequencing platform launch to Q2 2027, cuts 20% of workforce

Quantum-Si has delayed the launch of its Proteus protein sequencing platform to the second quarter of 2027 from the end of 2026, citing the need for an additional integrated instrument design cycle before production. The company is also cutting its workforce by approximately 20% to reduce cash burn and fund the revised development timeline. Chief Executive Officer Jeff Hawkins said the delay stems from an internal review of instrument performance, manufacturing processes, and supply-chain readiness. Testing of integrated units during the first half of 2026 revealed variability in performance across systems. Some instruments performed above internal specifications, while others met or fell slightly below targets. The additional design cycle will focus on improving repeatability across systems and making manufacturing changes to simplify production and improve yields.

Associated Press
Aug 13th, 2026
Quantum-Si delays Proteus launch to Q2 2027, cuts 20% of workforce to extend cash runway to Q4 2028

Quantum-Si has delayed the commercial launch of its Proteus protein sequencing platform to Q2 2027 and implemented a 20% workforce reduction to extend its cash runway into Q4 2028. The proteomics technology company reported second quarter revenue of $344,000, down from $591,000 in the prior year period. The company posted a net loss of $23.5 million for the quarter, compared to $28.8 million a year earlier. The launch delay incorporates an additional design cycle focused on manufacturing readiness and system repeatability. Chief executive Jeff Hawkins said testing has reinforced confidence in the technology, whilst the extra cycle will strengthen commercialisation readiness. Quantum-Si highlighted a $4 billion annual market opportunity in non-human proteomics, identified through work on agricultural applications and pathogen detection. The workforce reduction is expected to generate approximately $12 million in annualised savings whilst maintaining critical development resources.

Yahoo Finance
May 8th, 2026
Quantum-Si reports $258K Q1 revenue, advances Proteus protein sequencer for late-2026 launch

Quantum-Si reported first-quarter 2026 revenue of $258,000 and said the year would focus on development and market preparation for its next-generation Proteus protein sequencing platform, which is expected to launch commercially by year-end. The company completed sequencing on fully integrated Proteus instruments during the quarter, a milestone CEO Jeff Hawkins described as a significant de-risking event. Quantum-Si increased detectable amino acids from 15 to 17 within four months and aims to detect 18 amino acids at launch and all 20 during 2026. Proteus is expected to offer advantages over the current Platinum system, including automation, higher throughput and longer peptide read lengths. The company is also developing post-translational modification analysis capabilities for the platform.

Business Wire
May 7th, 2026
Quantum-Si achieves automated protein sequencing on Proteus, targets late 2026 launch

Quantum-Si, a proteomics technology company, reported first quarter 2026 revenue of $258,000 and a net loss of $21.7 million. The company announced successful sequencing on integrated Proteus instruments and sequenced its first customer samples on a prototype system, with its developmental kit now detecting 17 amino acids. Chief executive Jeff Hawkins said the company achieved automated sequencing runs on integrated Proteus instruments, bringing together instrumentation, KinetIQ Array, sequencing chemistry and data analysis. The company plans early access sites for Proteus instruments this summer ahead of commercial launch at year-end 2026. Quantum-Si held $190.4 million in cash and marketable securities as of 31 March, expected to fund operations into second quarter 2028. The company reiterated 2026 guidance of approximately $1.0 million revenue and adjusted operating expenses of $98.0 million or less.

Associated Press
May 7th, 2026
Quantum-Si achieves key Proteus milestones, eyes late 2026 launch with $190.5M cash runway

Quantum-Si, a proteomics technology company, reported first quarter 2026 revenue of $258,000 and announced significant progress on its Proteus protein sequencing platform. The company achieved automated sequencing runs on integrated Proteus instruments and sequenced its first customer samples on prototype systems. The company's developmental sequencing kit currently detects 17 amino acids. Quantum-Si plans to launch Proteus commercially by the end of 2026, with early access sites receiving instruments this summer. First quarter net loss was $21.7 million, compared to $19.2 million in the prior year. Operating expenses decreased to $24.1 million from $25.6 million. The company held $190.4 million in cash and marketable securities as of 31 March, expected to fund operations into the second quarter of 2028. Quantum-Si reiterated 2026 guidance of approximately $1 million revenue and $98 million or less in adjusted operating expenses.

Recently Posted Jobs

Sign up to get curated job recommendations

There are no jobs for Quantum-Si right now.

Find jobs on Simplify and start your career today

We update Quantum-Si's jobs every few hours, so check again soon! Browse all jobs →