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RTW Investments

Lifecycle-focused life sciences investor

Overview

RTW Investments, LP is a global life sciences investment firm that guides assets through the full investment lifecycle, from early research and company creation to venture and public-market investing. Its approach centers on science-led analysis to identify biopharmaceutical and medical technology assets with high growth potential and then allocates capital across stages, earning fees and performance-based rewards. The firm differentiates itself by combining early-stage company creation with later-stage and public-market investing, enabling long-term partnerships and deeper involvement across the company’s growth, with a global footprint in New York, London, and Shanghai. Its goal is to bring transformative therapies and medical technologies to commercialization, improving patient outcomes while delivering returns for its funds.

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About RTW Investments

Simplify's Rating
Why RTW Investments is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Venture CapitalFinancial ServicesBiotechnologyHealthcare

Company Size

N/A

Company Stage

N/A

Total Funding

$14.2B

Headquarters

New York City, New York

Founded

2010

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Simplify's take

What believers are saying

  • A 2026 portfolio surge produced multiple exits: Penumbra, Apogee, Lycia, Kailera, Aktis.
  • September 2026 NAV reached $2.70, with annualized +14.2% since October 2019.
  • Corxel's 2027 merger and $377 million financing extend runway through 2029.

What critics are saying

  • September 2026 NAV fell 7.7% monthly, lagging Nasdaq Biotech's gain.
  • RTW still has $54.3 million commitments, with Corxel absorbing $28.9 million.
  • RTW's strategy depends on fresh biotech exits; if IPOs shut, performance fees vanish.

What makes RTW Investments unique

  • Roderick Wong's science-led platform spans seed creation through public-market exits globally.
  • Corxel, Lycia, and Encoded show RTW creates and repeatedly finances winners.
  • RTW Biotech used 2026 IPOs, M&A, and SPACs across one lifecycle.

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Funding

Total Funding

$14.2B

Above

Industry Average

Funded Over

0 Rounds

Benefits

  • Health Insurance
  • Life Insurance
  • 401(k) Retirement Plan

Company News

SYMEX ECONOMICS SA
Nov 5th, 2026
Anaheim Bio |

With webdisclosure.com you can follow all financial news in real time from the best sources for publicly traded companies.

FinancialContent
Nov 4th, 2026
Lyell raises $80M in private placement to fund ronde-cel CAR T-cell therapy through BLA filing

Lyell Immunopharma has agreed to sell about $80 million of common stock in a private placement. Investors include ARCH Venture Partners, Adage Capital Management, Caligan Partners, and RTW Investments. The shares are priced at $10.77 each, and the deal is expected to close on or about November 4, 2026. The money should extend the cancer cell therapy company's cash runway into 2028. It will fund ronde-cel, a CD19/CD20 CAR T-cell candidate for relapsed or refractory large B-cell lymphoma, and the LYL273 colorectal cancer program. Lyell expects pivotal data on ronde-cel in mid-2027. It plans to file for US Food and Drug Administration approval in the second half of 2027.

wallstreet:online AG
Oct 23rd, 2026
Zai Lab raises $250M in TCGX-led PIPE to fund cancer drug zoci

Zai Lab, a biopharma company listed on Nasdaq and the Hong Kong exchange, has agreed to raise about $250 million in a private placement. It will sell 11,340,000 American Depositary Shares at $22.04 each, with each share representing ten ordinary shares. TCGX leads the round. Other investors include abrdn World Healthcare Fund, ADAR1 Capital Management, Balyasny Asset Management, Cormorant Asset Management, Frazier Life Sciences, RA Capital Management, RTW Investments, Sirenia Capital Management, Wellington Management, and Woodline Partners. Zai Lab will mainly use the proceeds to support global development of zocilurtatug pelitecan, its DLL3-targeting antibody-drug conjugate. The deal is expected to close on or about October 27, 2026.

CORXEL
Oct 16th, 2026
CORXEL Announces $287 million Series D1 Financing to Further Advance Its Cardiometabolic Pipeline including Oral Small Molecule GLP-1 Receptor Agonist

Berkeley Heights, NJ., Jan 22, 2026 – Corxel Pharmaceuticals Limited (CORXEL), a clinical-stage biopharmaceutical company dedicated to developing innovative therapies for patients with cardiometabolic conditions around the world, today announced the successful completion of its Series D1 financing, raising up to $287 million in capital. Proceeds from the round are expected to support the advancement of CX11, a differentiated oral small molecule GLP-1 RA for obese and overweight patients currently being evaluated in a Phase 2 trial conducted by CORXEL in the United States and a Phase 3 trial conducted by Vincentage in China, and other cardiometabolic programs, including for acute ischemic stroke and hypertension.

Associated Press
Sep 9th, 2026
Encoded Therapeutics raises $275M Series F to advance Dravet syndrome gene therapy into pivotal trials

Encoded Therapeutics has closed a $275 million Series F financing round co-led by GV and another healthcare fund. The clinical-stage biotechnology company develops precision genetic medicines for severe neurological disorders. The proceeds will fund a pivotal study of ETX101 in infants and young children with SCN1A+ Dravet syndrome, plus an expansion study for children and adolescents up to 18 years. The funding will also support commercial-scale GMP manufacturing and pipeline advancement, including ETX301 towards a 2027 Investigational New Drug submission for post-amputation neuroma pain. Participating investors include ARCH Venture Partners, Braidwell LP, Farallon Capital Management, Illumina Ventures, Invus, Janus Henderson Investors, Matrix Capital Management, Nolan Capital, RTW Investments, SoftBank Vision Fund 2, and Venrock.

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