RTW Investments

RTW Investments

Lifecycle-focused life sciences investor

Overview

RTW Investments, LP focuses on life sciences across the full investment lifecycle, moving assets from early research through commercialization. Its activities include creating companies from academic work, venture and crossover investing, and public-market positions, with discretionary advisory services for its Flagship and Innovation funds. The firm differentiates itself by combining early-stage company creation with later-stage and public-market investments, enabling long-term partnerships and deeper involvement, with offices in New York, London, and Shanghai. Its goal is to bring transformative biopharmaceutical and medical-technology assets to market, improving patient outcomes while delivering returns for its funds.

About RTW Investments

Simplify's Rating
Why RTW Investments is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Venture Capital

Financial Services

Biotechnology

Healthcare

Company Size

N/A

Company Stage

N/A

Total Funding

$13.4B

Headquarters

New York City, New York

Founded

2010

Get referred to RTW Investments

See people who can refer or advise you

Simplify Jobs

Simplify's Take

What believers are saying

  • Tarsus raised $125 million on August 7, 2026, with RTW participating.
  • RTW Biotech reported 35.7% underlying 2025 returns, boosting fundraising credibility in 2026.
  • iRhythm and Tarsus positions expanded in 2026, showing continued conviction in device winners.

What critics are saying

  • Biotech exits depend on FDA and M&A windows; 2026 deal markets already narrow.
  • RTW’s concentration in MDGL, INSM, PTGX, and PTCT exposes performance to four names.
  • Prolium’s PRO-203 and Candel’s aglatimagene still face binary clinical and approval risk.

What makes RTW Investments unique

  • Roderick Wong’s 2010 full-lifecycle model spans company creation through public markets.
  • RTW backed Prolium’s March 2026 launch and Candel’s February 2026 royalty deal.
  • RTW’s $10 billion biotech portfolio gives uncommon access across 88 positions.

Help us improve and share your feedback! Did you find this helpful?

Funding

Total Funding

$13.4B

Above

Industry Average

Funded Over

0 Rounds

Benefits

Health Insurance

Life Insurance

401(k) Retirement Plan

Company News

PR Newswire
Aug 10th, 2026
Avere Therapeutics raises $500M to advance once-weekly oral IL-23 therapy AVR-001

Avere Therapeutics announced a $500 million private placement to advance AVR-001, its once-weekly oral IL-23 receptor antagonist for inflammatory diseases. Leading healthcare investors including Venrock Healthcare Capital Partners, General Atlantic, Blackstone Multi-Asset Investing, and Wellington Management participated in the funding round. Combined with a previously announced $320 million concurrent private investment, the proceeds will fully fund Avere's operations through 2029. The financing will close alongside Avere's merger with NextCure, expected in the second half of 2026. Upon completion, the combined company will operate as Avere Therapeutics and trade on Nasdaq under ticker symbol "AVRX." Avere is initially developing AVR-001 for psoriasis, with potential expansion into ulcerative colitis, Crohn's disease, and psoriatic arthritis.

Central Charts
Aug 6th, 2026
Tarsus Pharmaceuticals raises $125M in oversubscribed PIPE financing to fund Alkeus acquisition

Tarsus Pharmaceuticals has secured $125 million through an oversubscribed private placement equity financing. The transaction includes participation from investors in Alkeus Pharmaceuticals, which Tarsus announced it would acquire earlier the same day. Notable investors include TCGX, Bain Capital Life Sciences, Wellington Management, ADAR1 Capital Management, Sirenia Capital Management LP, RTW Investments, and Vestal Point Capital. The company is selling 2,098,519 shares of common stock at $56 per share and pre-funded warrants to purchase 133,625 additional shares. The financing is expected to close on 7 August 2026. Tarsus intends to use the proceeds to fund clinical development, commercial activities, and general corporate purposes. Barclays is serving as lead placement agent, with BofA Securities and William Blair as co-placement agents.

StreetInsider
Jul 22nd, 2026
Mentari Therapeutics raises $200M to advance migraine prevention pipeline through Phase 2a readouts

Mentari Therapeutics, a biotechnology company developing migraine prevention therapies, has secured $200 million in a private placement from leading healthcare investors. The funding will support the development of Mentari's pipeline of targeted biologics for migraine treatment. Investors include Fairmount, ADAR1 Capital Management, Venrock Healthcare Capital Partners, Sirenia Capital Management, Janus Henderson Investors, Blackstone Multi-Asset Investing, RTW Investments, Deep Track Capital, Vivo Capital, Commodore Capital, BB Biotech, and others. The financing extends Mentari's cash runway into 2029 and through Phase 2a readouts on two PACAP-targeted lead programmes, including MT-002. The private placement will close immediately before Mentari's merger with InMed Pharmaceuticals and concurrently with a previously announced $290 million private placement. Jefferies, TD Cowen, Stifel, and Guggenheim Securities are acting as placement agents.

PR Newswire
Jul 22nd, 2026
Mentari Therapeutics Announces $200 Million Private Placement for Migraine Prevention Pipeline

/PRNewswire/ -- Mentari Therapeutics, Inc. ("Mentari"), a privately-held biotechnology company developing therapies for migraine prevention, today announced a...

GlobeNewswire
Jun 30th, 2026
Pyxis Oncology Announces Up to $114 Million Private Placement Financing to Advance MICVO Through Key Clinical Milestones

Expected to extend cash runway into the second quarter of 2027, supporting additional follow-up for 2L+ R/M HNSCC patients treated with MICVO at or below a...

Recently Posted Jobs

Sign up to get curated job recommendations

RTW Investments is Hiring for 5 Jobs on Simplify!

Find jobs on Simplify and start your career today

Don't see your dream role? Check out thousands of other roles on Simplify. Browse all jobs →