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Rejuvenate Bio

Gene therapies targeting aging and disease

Overview

Rejuvenate Bio develops gene therapies to treat aging and age-related diseases. It leverages Harvard-affiliated research on cellular reprogramming to design therapies that modify genes and cellular pathways linked to aging. The company plans to advance these therapies through clinical development and monetize via partnerships, licensing, and eventual direct sales after regulatory approval. Its goal is to extend healthspan and improve quality of life for elderly individuals and those with chronic age-related conditions.

Significant Headcount Growth

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About Rejuvenate Bio

Simplify's Rating
Why Rejuvenate Bio is rated
C+
Rated B on Competitive Edge
Rated C on Growth Potential
Rated C on Differentiation

Industries

BiotechnologyHealthcare

Company Size

11-50

Company Stage

Series A

Total Funding

$27.6M

Headquarters

San Diego, CA

Founded

2019

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What believers are saying

  • June 2026 financing raised $6 million from VCapital, Merck, Connecticut Innovations, and Digitalis.
  • October 2026 Wefunder signaled demand: 1,266 investors backed a $59.4 million pre-money round.
  • CB Insights lists six partnerships and $24.57 million total raised, improving commercialization leverage.

What critics are saying

  • August 2026 Form C showed only $3.3 million cash, forcing a near-term raise.
  • Companion-animal gene therapy still lacks lifespan proof, leaving safety and efficacy unproven by 2026.
  • No approved product exists; human clinical translation remains years away, and failure ends the company.

What makes Rejuvenate Bio unique

  • Harvard-born platform from George Church’s lab targets aging biology across species, not single diseases.
  • Rejuvenate Bio’s one-shot gene therapies emphasize durable expression and clinically validated gene targets.
  • Merck Animal Health partnered in June 2026, validating its animal-to-human translational strategy.

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Funding

Total Funding

$27.6M

Below

Industry Average

Funded Over

6 Rounds

Series A funding typically happens when a startup has a product and some customers, and now needs funding to scale. This money is usually used to grow the team, expand marketing, and improve the product. Venture capital firms are frequently the main investors here.
Series A Funding Comparison
Below Average

Industry standards

$15M
$6M
$8.2M
$15M
$30M

Growth & Insights and Company News

6 month growth

5%

1 year growth

5%

2 year growth

5%
Donga Science
Oct 27th, 2026
Global biotech firms develop gene therapies to extend pet lifespans.

Global biotech firms develop gene therapies to extend pet lifespans. Byeongku Lee 2026.10.27 15:45 KST Freeze-preservation services and anti-ageing drugs target cats and dogs in a US$150 billion pet health market Cats and dogs commonly kept as companion animals. Scientists and biotech companies are working on gene therapies and new anti-ageing drugs to extend the lifespans of companion animals. Getty Image Bank Research on animal longevity is emerging as a new field in life science. Scientists and biotech companies are developing gene therapies and new anti-ageing drugs to extend the lifespans of companion animals. Cryogenic preservation services, which keep pets at ultra-low temperatures with the aim of reviving them in the future, are also being offered. According to a report by the international journal 'Nature' on the 26th (local time), the first-ever 'Animal Longevity Summit' held in Toronto, Canada earlier this month brought together academic researchers and biotech industry figures to discuss a wide range of technologies, including cancer research in companion dogs, anti-ageing strategies for cats, gene therapies, and cryogenic preservation. According to the US venture capital (VC) firm Any VC, the pet and animal health market is estimated to be worth about US$150 billion (approximately 210 trillion won), and the growing interest and investment in extending human healthspan is now spreading to pets. Many of the current studies focus on dietary improvements, the use of probiotics, and applying existing human-approved medicines to animals. Some companies are working on new drugs that directly target ageing itself. Romanian biotech company CatHealthCompany is conducting clinical trials on two drug candidates designed to treat sarcopenia and kidney disease associated with ageing in cats. US biotech company Rejuvenate Bio is developing a gene therapy to treat mitral valve disease, a common heart condition in companion dogs. The company plans to eventually apply the therapy to treating metabolic diseases and extending lifespan. Belgian biotech company Genflow Biosciences is developing gene therapy technology aimed at reducing sarcopenia in dogs and extending their lifespans. The company intends to leverage the research results and funding it secures to move into the development of anti-ageing treatments for humans. However, gene therapies for companion animals are still at an early research stage, where their effectiveness in actually extending lifespan has yet to be sufficiently demonstrated, and therefore require further verification of both commercial viability and safety. In academia, some point out that government support for research on animal ageing is largely focused on outcomes that can be applied to human health, making collaboration with industry crucial for the development of actual therapeutics for companion animals. There is also growing interest in cryogenic preservation services that keep pets at ultra-low temperatures with the goal of reviving them in the future. US company CryoPets says it has around 12,000 customers on a waiting list for cryogenic preservation services. The company quotes a cost of about US$10,000 (approximately 13.2 million won) per cat and more than US$50,000 (about 66 million won) for large-breed dogs. However, there has so far been no successful case of reviving an animal or human that has undergone cryogenic preservation. <Reference> - doi.org/10.1038/d41586-026-03447-8 How do you feel about this article? No comments yet. Did you enjoy this article? Get more articles via email! Have an interesting science story, whistleblowing material, or tip? Don't hesitate to let Donga Science know.

Crowdfund Insider
Oct 19th, 2026
Rejuvenate Bio raises funds on Wefunder at a pre-money valuation of $59.4 million.

Rejuvenate Bio raises funds on Wefunder at a pre-money valuation of $59.4 million. October 19, 2026 @ 3:52 pm By JD Alois Rejuvenate Bio, a medtech firm researching proven anti-aging strategies in animals and eventually applying them to humans, is raising growth capital on Wefunder, with the round scheduled to close next week. According to the offering page, Rejuvenate Bio is raising more than $3.2 million under the Reg CF exemption. A concurrent funding round has already raised over $6 million and is matching the offering. The company is selling preferred equity held in an SPV at a $59.4 million pre-money valuation. The offering page indicates that more than 1,266 investors have backed the firm. The offering requires a minimum investment of $250 and a per-share price of $0.91. In total, the company reports having previously raised $36 million Rejuvenate Bio is developing a gene therapy that works in dogs and is being extended for potential use in people. The "one-shot gene therapies that target the root cause of aging and chronic disease." The treatment is said to be "reprogramming the body for youthful function." They report strong preclinical results: one therapy is said to repair cardiac damage while restoring metabolic health, and another is said to extend lifespan by several years. The global gene therapy market is hot, reaching $9.59 billion in 2025. Some anticipate the sector will hit $74.78 billion by 2035. There is already a plethora of supplements and clinical claims that seek to extend a viable, healthy. This is only going to grow. The founders are well established and have solid backgrounds that align with the firm's ambitions. Like most startups, the company is losing money. The Form C indicates they had around $3.3 million in cash on hand as of August 2026. For non-accredited investors, the terms are the same as for the ongoing Reg D. Have a crowdfunding offering you'd like to share? Submit an offering for consideration using its Submit a Tip form and Crowdfundinsider may share it on its site! Sponsored Links by DQ Promote Reg A - Form 1-A filings Beta. Beta. Initial Form 1-A only. Target raise is the stated Amount to be Raised, totaled. Compared with the same dates one year earlier. YTD: Jan 1, 2026 - Oct 19, 2026 vs Jan 1, 2025 - Oct 19, 2025 Number of Filings 129 Prior 123 +4.9% Target Raise, Total $3.37B Prior $3.45B -2.2% | / | This YTD | Year prior | Change | | Filings | 129 | 123 | +4.9% | | Target raise | $3.37B | $3.45B | -2.2% | Sponsored by the Crowded Media Group the leading digital news service covering the global Fintech Industry, including digital assets, crowdfunding, tokenization, and other innovations in capital markets. email Crowdfundinsider @CrowdfundInside This display counts initial Form 1-A filings only. It does not represent subsequent filings, including Form 1-A/A amendments or Form 1-A POS post-qualification updates filed by the issuer. Amounts are the stated Amount to be Raised on the initial filing, not capital raised and not amounts revised in later filings.

SBIR.gov
Sep 13th, 2026
Awards | SBIR

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AgeTech.com
Jun 24th, 2026
Rejuvenate Bio secures new funding and Merck partnership in anti-aging gene therapy push.

Rejuvenate Bio secures new funding and Merck partnership in anti-aging gene therapy push. Rejuvenate Bio lands fresh investment and a Merck partnership, signaling growing pharma confidence in gene therapy approaches to aging. 2026-06-24 Rejuvenate Bio, a longevity-focused biotech developing gene therapy interventions targeting the biology of aging, has secured new funding alongside a strategic partnership with pharmaceutical giant Merck, according to reporting from Longevity.Technology. The announcement marks one of the more significant validation moments for the aging gene therapy field in recent months, with a major established pharma player now formally aligned with a company working at the frontier of biological age reversal. For industry observers, the Merck partnership carries particular weight. Large pharmaceutical companies have historically maintained a cautious distance from longevity biotechs, preferring to watch the science mature before committing resources. A named partnership with Merck suggests that calculus is shifting. Whether the collaboration involves co-development, licensing arrangements, or research access remains to be detailed publicly, but the signal it sends to the broader agetech and longevity investment community is difficult to overstate. Rejuvenate Bio has built its platform around gene therapy approaches that aim to address aging at a systemic level rather than targeting individual age-related diseases in isolation. The company's scientific foundation draws on work exploring how specific gene interventions can influence biological processes associated with aging across multiple organ systems simultaneously. This systems-level framing has distinguished Rejuvenate Bio from many peers in the longevity biotech space who focus on single-pathway or single-disease approaches. The timing of this announcement fits within a broader pattern of accelerating institutional interest in longevity biotechnology through 2025 and into 2026. Funding rounds across the sector have grown in both frequency and scale, and the entry of established pharmaceutical partners into formal collaborations represents the next logical phase of market maturation. For agetech professionals working in adjacent areas - from senior living technology to AI-enabled care platforms - the continued validation of the longevity biotech space reinforces the overall investment narrative around aging as a defining market category. The practical implications for near-term clinical translation are still developing. Gene therapy approaches to aging face meaningful regulatory and safety questions that will take years of clinical work to resolve. However, partnerships like the one announced between Rejuvenate Bio and Merck typically accelerate that process by bringing additional scientific infrastructure, regulatory experience, and capital to bear on exactly those challenges. As the agetech industry continues to expand across both care technology and longevity science, deals of this nature serve as important connective tissue between the cutting edge of research and the commercial pathways that will eventually deliver interventions to aging populations at scale. Get the AgeTech Digest Funding rounds, product launches, and industry moves - every week, free.

Newswire
Jun 11th, 2026
Lifespan portfolio company Rejuvenate Bio closes $6 million financing and R&D collaboration with Merck Animal Health.

Lifespan portfolio company Rejuvenate Bio closes $6 million financing and R&D collaboration with Merck Animal Health. Jun 11, 2026, 09:59 ET Milestone financing and R&D collaboration advances gene therapy programs targeting chronic and age-related diseases in companion animals. NORWALK, Conn., June 11, 2026 /CNW/ - Lifespan Vision Ventures (LVV), an investment firm focused on therapeutics that improve human healthspan, congratulates its portfolio company Rejuvenate Bio on the successful close of a $6 million financing round and the announcement of a strategic research and development collaboration with Merck Animal Health. The financing round was led by VCapital, with participation from Merck Animal Health, Connecticut Innovations, and Digitalis. Proceeds will support continued advancement of Rejuvenate Bio's gene therapy platform and pipeline, including treatments designed to address chronic and age-associated diseases in companion animals. Alongside the financing, Rejuvenate Bio and Merck Animal Health have entered into a strategic R&D collaboration focused on advancing a novel gene therapy program in animal health, leveraging Rejuvenate Bio's proprietary platform technologies and translational expertise. Andrew Worden, Founding Partner at Lifespan Vision Ventures stated, "We are proud to see Rejuvenate Bio reach this important milestone. The confidence shown by Merck Animal Health - both as an investor and a collaborator - speaks to the strength of the team and the promise of their science. Lifespan Vision Ventures is delighted to continue supporting their mission to address some of the most significant unmet needs in companion animal and human health." Rejuvenate Bio is developing gene therapies aimed at extending healthy lifespan and treating chronic diseases across both veterinary and human health applications. The company's approach focuses on modifying biological pathways associated with aging through targeted genetic interventions. About Lifespan Vision Ventures Lifespan Vision Ventures is a global venture capital firm investing in early-stage biotechnology companies developing breakthrough technologies to prevent and treat age-related diseases. The firm partners with visionary founders advancing science-driven solutions that promote healthy aging and extend human healthspan. About Rejuvenate Bio Rejuvenate Bio is a biotechnology company dedicated to developing novel gene therapies for chronic age-related diseases. Rejuvenate Bio has built a gene therapy pipeline with huge potential in chronic disease by utilizing clinically validated gene targets and a delivery approach that ensures well tolerated, durable expression. Founded on scientific research developed at the Wyss Institute at Harvard Medical School, Rejuvenate Bio has developed groundbreaking therapies to treat chronic age-related disease in both humans and animals. The company is headquartered in San Diego, CA. SOURCE LifeSpan Vision Ventures

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