ReNAgade Therapeutics

ReNAgade Therapeutics

Develops RNA medicines for gene therapy

About

ReNAgade Therapeutics focuses on RNA medicine, aiming to address challenges in delivering RNA therapies to specific tissues and creating a comprehensive therapeutic platform. The company has developed a unique toolkit that enables precise correction of diseases on a large scale. Their business model leverages proprietary delivery technologies to access previously unreachable cells, achieved through a partnership with Orna Therapeutics. Unlike traditional gene therapy, which typically replaces defective genes, ReNAgade's approach seeks to permanently correct faulty genes, allowing for the insertion of larger genes or exons. This positions ReNAgade as a leader in the next generation of gene therapy, targeting diseases at their genetic source rather than just alleviating symptoms. The company serves the medical and healthcare sectors, generating revenue through joint ventures, licensing its technologies, and potentially developing its own therapeutic products.

Company Stage

Series A

Employees

51-200

Industries

Biotechnology, Healthcare

Total Funding

$291.8M

Headquarters

Cambridge, Massachusetts

Founded

2021


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Simplify's Take

What believers are saying

  • Acquisition by Orna Therapeutics enhances ReNAgade's circular RNA capabilities.
  • GanNA Bio collaboration expands therapeutic reach with extra-hepatic delivery technology.
  • Participation in ASGCT meeting boosts visibility and potential partnerships.

What critics are saying

  • Integration challenges post-acquisition may disrupt operations and delay timelines.
  • Focus on glycobiology may divert resources from core RNA therapeutic development.
  • Dependency on GanNA Bio's research outcomes could lead to delays or setbacks.

What makes ReNAgade Therapeutics unique

  • ReNAgade's all-RNA system enables precise gene correction and insertion.
  • Partnership with Orna Therapeutics enhances RNA delivery through circular RNA expertise.
  • Proprietary toolkit unlocks previously inaccessible cells for RNA-based therapies.

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Growth & Insights
Headcount

6 month growth

22%

1 year growth

-18%

2 year growth

22%

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