Revalia Bio

Revalia Bio

Ex vivo organ research platform services

Overview

Revalia Bio uses an ex vivo human organ research platform to provide contract research services for the biopharmaceutical industry. The platform lets researchers study human organs outside the body in a controlled setting, enabling evaluation of drug targets, optimization of lead compounds, and preclinical development across diseases like cancer, cardiovascular, and infectious diseases. Unlike traditional models that rely on non-human systems, Revalia Bio focuses on human organ tissue to generate data that can faster inform drug development. The company differentiates itself through its specialized ex vivo organ platform and services (target validation, lead optimization, preclinical studies) offered as contract research. Its goal is to shorten the drug development timeline and reduce costs by providing human-organ–based testing to pharmaceutical and biotech clients.

About Revalia Bio

Simplify's Rating
Why Revalia Bio is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & Analytics

Consulting

Biotechnology

Healthcare

Company Size

11-50

Company Stage

Seed

Total Funding

$14.5M

Headquarters

New Haven, Connecticut

Founded

2022

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Simplify's Take

What believers are saying

  • September 2026 brought ex-Lilly and Verily CEO Casimir Starsiak to scale partnerships.
  • FDA's 2025 animal-testing rollback accelerates adoption of human-data preclinical tools.
  • Two top-10 pharma customers and revenue quadrupling since 2023 signal early market fit.

What critics are saying

  • Revalia still depends on scarce non-transplantable organs and OPO consent workflows.
  • Commercial traction remains thin; 2025 revenue was $5.9 million, mostly pilots.
  • Altis Labs, Emulate, and organoid platforms compete for the same pharma budgets.

What makes Revalia Bio unique

  • Revalia's donated-human-organ perfusion data beats animal models on physiological relevance.
  • ARPA-H's $26.7 million CATALYST award validates Revalia's Human Data Trials platform.
  • Ex vivo organs and organ-on-chip multimodal datasets create a harder-to-replicate research moat.

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Funding

Total Funding

$14.5M

Above

Industry Average

Funded Over

1 Rounds

Seed funding is usually the first official round after pre-seed, when a startup has a prototype or concept. It’s typically used to develop the product, test the market, and start building the team. Investors here are often angel investors or early-stage venture capitalists.
Seed Funding Comparison
Above Average

Industry standards

$3.3M
$2M
Netflix
$2.3M
Instacart
$3M
Robinhood
$14.5M
Revalia Bio

Benefits

Flexible Work Hours

Health Insurance

Dental Insurance

Vision Insurance

Disability Insurance

Wellness Program

Paid Sick Leave

Paid Vacation

Growth & Insights and Company News

Headcount

6 month growth

↑ 2%

1 year growth

↑ 0%

2 year growth

↑ 0%
Hartford Business
Sep 16th, 2026
Yale bioscience spinout Revalia Bio names Eli Lilly exec CEO.

Yale bioscience spinout Revalia Bio names Eli Lilly exec CEO. September 16, 2026 New Haven-based Yale University spinout Revalia Bio announced Wednesday that it has named a former Eli Lilly executive as its new president and CEO. Casimir "Caz" Starsiak III will now lead the bioscience company as it looks to expand its pharmaceutical partnerships and commercial operations. Starsiak, who took over on Sept. 1, succeeds co-founder Greg Tietjen, who moved into the newly created role of chief innovation officer. Starsiak most recently served as associate vice president of enterprise AI and research software product management at Indianapolis-based Eli Lilly. He led teams developing software supporting drug discovery and clinical trials, including artificial intelligence products. Previously, Starsiak was senior vice president of product and operations at diagnostics company Genalyte and spent more than six years at Verily, Alphabet's life sciences company. His roles there included general manager of the Baseline clinical trials platform. At Revalia, Starsiak will focus on commercial expansion, pharmaceutical partnerships and scaling operations. Tietjen, meanwhile, will oversee integration of the company's research, technology and product development. Tietjen and Starsiak will work with co-founder and Chief Operating Officer Jenna DiRito as Revalia expands its research capacity and pharmaceutical relationships. Revalia uses perfusion technology to keep donated human organs functioning outside the body, allowing researchers to study how experimental drugs behave in human organs before entering clinical trials. The company uses organs obtained through organ procurement organizations with donor-family consent after they have been deemed unsuitable for transplantation. Starsiak said his goal is to make data generated from functioning human organs an integral part of pharmaceutical drug development.

Yahoo Finance
Sep 16th, 2026
Revalia Bio names former Lilly and Verily exec Casimir Starsiak III as CEO to scale human organ research platform

Revalia Bio, which generates drug development data using functioning donated human organs, has appointed Casimir Starsiak III as president and chief executive officer. Co-founder Greg Tietjen transitions to chief innovation officer to focus on research and technology integration. Starsiak will lead commercial expansion, pharmaceutical partnerships, and operational scaling. He brings experience from the intersection of technology and life sciences. Revalia uses perfusion technology to keep donated organs viable outside the body for research. The organs come from organ procurement organisations with donor consent after being deemed unsuitable for transplant. The company's platform aims to provide human-centred data for drug development before clinical trials. This approach addresses limitations of animal studies and cell cultures in predicting how therapies behave in human organs. Revalia previously secured funding and received an ARPA-H Catalyst award.

PharmiWeb
Dec 5th, 2025
Revalia Bio wins $26.7M ARPA-H contract to advance human-first drug trials

Revalia Bio has been awarded a contract worth up to $26.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to advance drug development using human data trials. The New Haven-based company will serve as technical lead for the project under ARPA-H's CATALYST programme. Revalia will develop AI-driven models trained on Human Data Trials, which use living systems derived from donated human organs, organ-on-chip platforms and multimodal datasets. The approach aims to reduce reliance on animal testing and better predict drug behaviour in humans, potentially cutting late-stage failures and accelerating therapy development. The company's Human Data Trial platform transforms donated organs into actionable insights for drug safety and efficacy predictions before clinical trials. CEO Greg Tietjen described the award as validation that "the era for human data is here".

HIT Consultant
Sep 5th, 2025
Revalia Bio Launches 'Human Data Trials' with $14.5M to Transform Drug Development

- Revalia Bio Inc., a new pre-clinical research company secures $14.5M in seed funding round to support the launch of its "Human Data Trials".

Associated Press
Sep 4th, 2025
Revalia Bio Raises $14.5M for Human Trials

Revalia Bio raised $14.5 million in a seed round to launch its Human Data Trials platform, which uses real human organs for pre-clinical research. The funding was co-led by America's Frontier Fund and Sierra Ventures. Revalia's approach aims to improve drug development accuracy and reduce costs by using data from perfused human organs. The company has quadrupled its revenue since 2023 and signed two top pharmaceutical companies as customers. Total funding now stands at $19.5 million.

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