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Revalia Bio uses an ex vivo human organ research platform to provide contract research services for the biopharmaceutical industry. The platform lets researchers study human organs outside the body in a controlled setting, enabling evaluation of drug targets, optimization of lead compounds, and preclinical development across diseases like cancer, cardiovascular, and infectious diseases. Unlike traditional models that rely on non-human systems, Revalia Bio focuses on human organ tissue to generate data that can faster inform drug development. The company differentiates itself through its specialized ex vivo organ platform and services (target validation, lead optimization, preclinical studies) offered as contract research. Its goal is to shorten the drug development timeline and reduce costs by providing human-organ–based testing to pharmaceutical and biotech clients.
Industries
Data & Analytics
Consulting
Biotechnology
Healthcare
Company Size
11-50
Company Stage
Seed
Total Funding
$14.5M
Headquarters
New Haven, Connecticut
Founded
2022
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Total Funding
$14.5M
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Yale bioscience spinout Revalia Bio names Eli Lilly exec CEO. September 16, 2026 New Haven-based Yale University spinout Revalia Bio announced Wednesday that it has named a former Eli Lilly executive as its new president and CEO. Casimir "Caz" Starsiak III will now lead the bioscience company as it looks to expand its pharmaceutical partnerships and commercial operations. Starsiak, who took over on Sept. 1, succeeds co-founder Greg Tietjen, who moved into the newly created role of chief innovation officer. Starsiak most recently served as associate vice president of enterprise AI and research software product management at Indianapolis-based Eli Lilly. He led teams developing software supporting drug discovery and clinical trials, including artificial intelligence products. Previously, Starsiak was senior vice president of product and operations at diagnostics company Genalyte and spent more than six years at Verily, Alphabet's life sciences company. His roles there included general manager of the Baseline clinical trials platform. At Revalia, Starsiak will focus on commercial expansion, pharmaceutical partnerships and scaling operations. Tietjen, meanwhile, will oversee integration of the company's research, technology and product development. Tietjen and Starsiak will work with co-founder and Chief Operating Officer Jenna DiRito as Revalia expands its research capacity and pharmaceutical relationships. Revalia uses perfusion technology to keep donated human organs functioning outside the body, allowing researchers to study how experimental drugs behave in human organs before entering clinical trials. The company uses organs obtained through organ procurement organizations with donor-family consent after they have been deemed unsuitable for transplantation. Starsiak said his goal is to make data generated from functioning human organs an integral part of pharmaceutical drug development.
Revalia Bio, which generates drug development data using functioning donated human organs, has appointed Casimir Starsiak III as president and chief executive officer. Co-founder Greg Tietjen transitions to chief innovation officer to focus on research and technology integration. Starsiak will lead commercial expansion, pharmaceutical partnerships, and operational scaling. He brings experience from the intersection of technology and life sciences. Revalia uses perfusion technology to keep donated organs viable outside the body for research. The organs come from organ procurement organisations with donor consent after being deemed unsuitable for transplant. The company's platform aims to provide human-centred data for drug development before clinical trials. This approach addresses limitations of animal studies and cell cultures in predicting how therapies behave in human organs. Revalia previously secured funding and received an ARPA-H Catalyst award.
Revalia Bio has been awarded a contract worth up to $26.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to advance drug development using human data trials. The New Haven-based company will serve as technical lead for the project under ARPA-H's CATALYST programme. Revalia will develop AI-driven models trained on Human Data Trials, which use living systems derived from donated human organs, organ-on-chip platforms and multimodal datasets. The approach aims to reduce reliance on animal testing and better predict drug behaviour in humans, potentially cutting late-stage failures and accelerating therapy development. The company's Human Data Trial platform transforms donated organs into actionable insights for drug safety and efficacy predictions before clinical trials. CEO Greg Tietjen described the award as validation that "the era for human data is here".
- Revalia Bio Inc., a new pre-clinical research company secures $14.5M in seed funding round to support the launch of its "Human Data Trials".
Revalia Bio raised $14.5 million in a seed round to launch its Human Data Trials platform, which uses real human organs for pre-clinical research. The funding was co-led by America's Frontier Fund and Sierra Ventures. Revalia's approach aims to improve drug development accuracy and reduce costs by using data from perfused human organs. The company has quadrupled its revenue since 2023 and signed two top pharmaceutical companies as customers. Total funding now stands at $19.5 million.
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Industries
Data & Analytics
Consulting
Biotechnology
Healthcare
Company Size
11-50
Company Stage
Seed
Total Funding
$14.5M
Headquarters
New Haven, Connecticut
Founded
2022
Find jobs on Simplify and start your career today