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Rezo Therapeutics

Maps disease networks to precision therapies

Overview

Rezo Therapeutics maps disease networks to develop precision medicines. Its SSD platform combines proteomics, genetics, structural biology, chemistry, and bioinformatics to build maps of molecular disease networks and identify druggable targets, with a focus on solid tumors. Unlike single-target approaches, it maps whole networks to reveal tumor-specific vulnerabilities and guide therapy development, supported by UCSF QBI origins. The goal is to translate network biology into a pipeline of targeted therapeutics through internal programs and strategic partnerships.

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About Rezo Therapeutics

Simplify's Rating
Why Rezo Therapeutics is rated
C+
Rated B on Competitive Edge
Rated C on Growth Potential
Rated C on Differentiation

Industries

Data & AnalyticsAI & Machine LearningBiotechnologyHealthcare

Company Size

11-50

Company Stage

Series A

Total Funding

$78M

Headquarters

San Francisco, California

Founded

2021

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Simplify's Take

What believers are saying

  • Google-backed modeling work in January 2026 suggests stronger computational infrastructure.
  • Cristiana Guiducci's CSO appointment adds oncology discovery credibility from Nurix and immunology.
  • Forty employees and continued leadership changes indicate ongoing program investment through 2026.

What critics are saying

  • Rezo still has no disclosed clinical candidates or human data as of August 2026.
  • Zero active job postings in 2026 signal slowed hiring and possible capital conservation.
  • If SSD never yields a clinical asset, Rezo becomes a platform story without product traction.

What makes Rezo Therapeutics unique

  • Rezo's SSD platform combines proteomics, genetics, chemistry, and bioinformatics for network mapping.
  • UCSF founders Nevan Krogan and Kevan Shokat anchor unusually deep academic disease-biology expertise.
  • Derek Hicks joined as CEO in August 2025, adding Pfizer, Spark, and Intellia experience.

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Funding

Total Funding

$78M

Above

Industry Average

Funded Over

1 Rounds

Notable Investors:
Series A funding typically happens when a startup has a product and some customers, and now needs funding to scale. This money is usually used to grow the team, expand marketing, and improve the product. Venture capital firms are frequently the main investors here.
Series A Funding Comparison
Above Average

Industry standards

$15M
$8.2M
$15M
$30M
$78M

Benefits

  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • 401(k) Retirement Plan
  • Commuter Benefits
  • Health Savings Account/Flexible Spending Account
  • Dependent care Flexible Spending Account
  • Parental Leave
  • Flexible Work Hours
  • Paid Holidays

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

0%

2 year growth

2%
The Pharma Letter
Aug 12th, 2025
Rezo Therapeutics appoints Derek Hicks as CEO

US biotech Rezo Therapeutics today announced the appointment of Derek Hicks as its chief executive (CEO).

Business Wire
Jul 18th, 2024
Rezo Therapeutics Appoints Cristiana Guiducci, Ph.D., as Chief Scientific Officer

Rezo Therapeutics appoints Cristiana Guiducci, Ph.D., as chief scientific officer.

BioSpace
Sep 20th, 2023
Rezo Therapeutics Appoints Nadir Mahmood, Ph.D., as Chief Executive Officer

Rezo Therapeutics appoints Nadir Mahmood, Ph.D., as chief executive officer.

GenomeWeb
Nov 17th, 2022
Rezo Therapeutics Launches With $78M in Series A Funding

The firm will initially focus on developing a pipeline of biomarker-guides therapies for solid tumors.

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