Sleep BioSeries™ technology is clinically proven to provide time-release sleep support, and is shown to help fall asleep faster, achieve better deep sleep patterns and help wake up fresh and rested.*† †† ◆LOS ANGELES, Aug. 23, 2024 /PRNewswire/ -- Ritual , the traceable health and wellness brand working to raise the safety and efficacy standards in the supplement industry, announced the completion of a clinical trial on its Sleep BioSeries™ Melatonin , a sleep support supplement formulated with 5mg of pure Italian melatonin, proven to support the natural cycle of sleep-wake patterns.*†Sleep BioSeries™ Melatonin is clinically shown to reach peak melatonin levels faster than placebo and promote sustained melatonin levels in the blood throughout the night before tapering off at the 6-hour mark towards morning.*†"Melatonin products on the market are mostly either instant-release, which can help you fall asleep quickly but may wear off soon, or slow/extended-release, which provide sustained support but may lack the immediate effect needed to fall asleep," said Mastaneh Sharafi Ph.D., R.D., Senior Vice President of Science and Innovation at Ritual. "We formulated Sleep BioSeries™ with our innovative BioSeries™ technology to provide both immediate and sustained support, to promote better sleep patterns. We're proud to have demonstrated the efficacy of this technology in a pharmacokinetic and 2-week supplementation clinical trial."*††The randomized, double-blind, placebo-controlled, crossover design was used to assess the pharmacokinetics (N=10) and 2-week supplementation (N=12) effects of Sleep BioSeries™ Melatonin. Participants were adults ranging in age from 18 to 31 with reported sleep difficulty.*With 1mg of instant release Melatonin in the first tablet to support falling asleep, Sleep BioSeries™ Melatonin is clinically shown to reduce time to fall asleep by 43% .* ‡‡With 3mg of extended release Melatonin in the second tablet to support restful sleep. Sleep BioSeries™ Melatonin is clinically proven to support better deep sleep patterns.* ††With 1 mg of extended Melatonin in the third tablet that tapers off by the morning

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