SOPHiA GENETICS

SOPHiA GENETICS

Cloud-based AI platform for genomic analytics

Overview

Sophia Genetics provides a cloud-based platform called SOPHiA DDM that uses AI and machine learning to analyze digital health data, especially genomic profiles, for healthcare providers, researchers, and pharma companies. It standardizes, computes, and analyzes multimodal data to support diagnosis, therapy selection, analysis, and drug development. Customers own their data and can share insights through the platform, contributing to collective intelligence. The platform is charged on a subscription or access basis, creating a global data-driven medicine ecosystem. The company differentiates itself by enabling data ownership for users, facilitating data sharing among institutions, and handling complex multimodal genomic data to drive better patient outcomes.

About SOPHiA GENETICS

Simplify's Rating
Why SOPHiA GENETICS is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & Analytics

AI & Machine Learning

Healthcare

Company Size

501-1,000

Company Stage

IPO

Headquarters

Saint-Sulpice, Switzerland

Founded

2011

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Simplify's Take

What believers are saying

  • Q2 2026 revenue rose 27% to $23.3 million, raising full-year guidance.
  • Liquid biopsy momentum accelerated: Synnovis expects about 7,000 UK patients yearly.
  • Ross Muken took CEO July 1, 2026, preserving execution continuity and commercial focus.

What critics are saying

  • Q2 2026 headcount reductions signal ongoing pressure to fund growth efficiently.
  • Two equity offerings in 2026 diluted holders before profitability emerged.
  • Guardant, Roche, and large diagnostics incumbents can outcompete if global CDx adoption stalls.

What makes SOPHiA GENETICS unique

  • SOPHiA DDM analyzes genomic and multimodal data across 1,000+ institutions in 75 countries.
  • AstraZeneca selected SOPHiA for two 2026 companion diagnostics programs.
  • MSK and SOPHiA are building a New York precision oncology hub.

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Funding

Total Funding

$580.1M

Above

Industry Average

Funded Over

10 Rounds

Post IPO Equity funding comparison data is currently unavailable. We're working to provide this information soon!
Post IPO Equity Funding Comparison
Coming Soon

Benefits

Health Insurance

Dental Insurance

Vision Insurance

401(k) Company Match

Disability Insurance

Commuter Benefits

Paid Vacation

Paid Sick Leave

Paid Holidays

Hybrid Work Options

Meal Benefits

Stock Price

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

1%

2 year growth

0%
Newswire
Aug 4th, 2026
SOPHiA GENETICS enters collaboration to develop Companion Diagnostics for precision oncology therapies.

SOPHiA GENETICS enters collaboration to develop Companion Diagnostics for precision oncology therapies. Aug 04, 2026, 06:15 ET BOSTON and ROLLE, Switzerland, Aug. 4, 2026 /CNW/ - SOPHiA GENETICS (NASDAQ: SOPH) today announced a new global collaboration to develop, validate, and deploy two companion diagnostics (CDx) supporting precision oncology therapies with AstraZeneca (LSE/STO/NYSE: AZN). This multi-year collaboration agreement will advance the development and commercialization of two companion diagnostic programs, bringing SOPHiA GENETICS's decentralized clinical trial assays and companion diagnostic capabilities to AstraZeneca therapies. As part of the collaboration, SOPHiA GENETICS will develop its Solid Tumor application into a decentralized companion diagnostic. In addition, the company will develop and validate its Hematological Oncology application to support a companion diagnostic program for patients with blood cancer. "A breakthrough therapy only matters to the patients we can find in time to treat. We are moving towards a future that no longer depends on geography, where any laboratory can run the same test to the same high standard on day one of a launch. We believe these programs are what that future looks like in practice. Bringing the right therapy to the right patient, in any country and any laboratory, is the work that will define the next generation of precision medicine," said Ross Muken, CEO, SOPHiA GENETICS. By combining accurate biomarker detection with rapid deployment, SOPHiA GENETICS aims to shorten the distance between a new therapy and the patients who need it. Through its global data-driven platform, insights generated from patient populations can help advance informed clinical decision-making across healthcare systems. This vision of connected, data-driven medicine underpins these programs, with the goal of expanding access to innovative treatments and improving outcomes for patients worldwide. About SOPHiA GENETICS Companion Diagnostics SOPHiA GENETICS end-to-end diagnostic capabilities span the drug development and launch continuum: * Clinical Trial Assay (CTA) development, to identify, screen, and enroll the right patients quickly and accurately during a trial. * Companion Diagnostic (CDx) development, validation, and regulatory submission, taking an assay from research use through analytical and clinical validation to approval in the US, EU, Japan, and beyond. * Deployment through the SOPHiA DDM(TM) Platform and the SOPHiA DDM(TM) MaxCare Program, enabling laboratories to bring testing in-house and adopt new genomic applications with confidence, reaching larger populations around the globe. SOPHiA GENETICS's technology-agnostic, cloud-based platform lets healthcare institutions run the same validated, AI-powered analysis locally, while sharing and benefiting from the collective intelligence of a global network of more than 1,000 connected institutions across over 75 countries. For a pharmaceutical partner preparing a global launch, that means a companion diagnostic that can be available in the local lab on day one of drug approval. About SOPHiA GENETICS SOPHiA GENETICS (Nasdaq: SOPH) is an AI-native healthcare technology company on a mission to transform patient care by expanding access to data-driven medicine globally. It is the creator of SOPHiA DDM(TM), an AI platform that analyzes complex genomic and multimodal data to generate real-time, real-world insights for a broad global network of hospital, laboratory, and biopharma institutions. For more information, visit SOPHiAGENETICS.COM and connect with us on LinkedIn. SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact [email protected] to obtain the appropriate product information for your country of residence. SOPHiA GENETICS Forward-Looking Statements: This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management's beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements. SOURCE SOPHiA GENETICS Media and Investor Contact: Kellen Sanger, [email protected]; [email protected]

PR Newswire
Aug 4th, 2026
SOPHiA GENETICS raises 2026 revenue guidance after Q2 growth and $57.5M offering

SOPHiA GENETICS reported second quarter 2026 revenue of $23.3 million, up 27% year-over-year. The AI-driven precision medicine company raised its full-year revenue guidance to $94 million to $96 million, representing 22% to 24% growth, up from a prior range of $92 million to $94 million. Net loss remained flat at $22.4 million year-over-year, whilst adjusted EBITDA loss improved 27% to $8.8 million. Gross margin was 64.6% on a reported basis and 72.1% on an adjusted basis. The company performed a record 115,000 analyses on its SOPHiA DDM platform, with 60% volume growth in the US and 70% growth in liquid biopsy. SOPHiA GENETICS signed two companion diagnostic programmes with AstraZeneca, its first such partnerships. The company completed an oversubscribed $57.5 million public offering in Q2, bringing cash and cash equivalents to $107.7 million.

PR Newswire
Jun 22nd, 2026
SOPHiA GENETICS appoints Ross Muken as CEO, co-founder Jurgi Camblong becomes executive chairman

SOPHiA GENETICS, a global leader in AI-driven precision medicine, has announced that shareholders at its 2026 Annual General Meeting approved all proposals. Co-founder Dr Jurgi Camblong was elected Executive Chairman of the Board with 99.79% of votes, whilst Ross Muken was elected to the Board with 99.88% and will become CEO effective 1 July 2026. Dr Camblong, who founded the company and served as CEO for 15 years, will focus on long-term strategic, scientific and technological direction. The Board introduced a Lead Independent Director role rotating annually among independent committee chairs. Shareholders also approved the 2025 financial statements, management compensation proposals, and amendments to the Articles of Association. PricewaterhouseCoopers was re-elected as external auditor.

PR Newswire
Jun 17th, 2026
SOPHiA GENETICS announces pricing of $50 million public offering of ordinary shares.

SOPHiA GENETICS announces pricing of $50 million public offering of ordinary shares. Jun 16, 2026, 21:21 ET BOSTON and ROLLE, Switzerland, June 16, 2026 /PRNewswire/ - SOPHiA GENETICS (Nasdaq: SOPH), a global leader in Ai-driven precision medicine, announced today the pricing of its previously announced underwritten public offering of 10,526,000 ordinary shares at a public offering price of $4.75 per ordinary share. The gross proceeds from the offering, before deducting the underwriting discounts and commissions and estimated offering expenses payable by the Company are expected to be approximately $50 million. All of the ordinary shares to be sold in the proposed offering will be sold by the Company. In addition, the Company has granted the underwriters a 30-day option to purchase up to 1,578,900 additional ordinary shares at the public offering price, less the underwriting discounts and commissions. The offering is expected to close on June 18, 2026, subject to customary closing conditions. TD Cowen is acting as the lead book-running manager for the offering. Guggenheim Securities is acting as book-running manager, and BTIG and Craig-Hallum are acting as lead managers for the offering. A registration statement on Form F-3 (File No. 333-289266) relating to the ordinary shares and other securities of the Company has been filed with the U.S. Securities and Exchange Commission (the "SEC") and was declared effective on August 15, 2025. The offering may be made only by means of a prospectus supplement and accompanying prospectus. A preliminary prospectus supplement and accompanying prospectus relating to this offering has been filed with the SEC and a final prospectus supplement and accompanying prospectus relating to the offering will be filed with the SEC. Electronic copies of the final prospectus supplement and accompanying prospectus will be available on the SEC's website located at www.sec.gov. Copies of the final prospectus supplement and accompanying prospectus relating to this offering, when available, may be obtained for free by contacting TD Securities (USA) LLC, c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717 or by email at [email protected]. This press release shall not constitute an offer to sell or a solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction. Any offers, solicitations or offers to buy, or any sales of securities will be made in accordance with the registration requirements of the Securities Act of 1933, as amended. There is no intention or permission to publicly offer, solicit, sell or advertise, directly or indirectly, any securities of SOPHiA GENETICS SA, such as the ordinary shares, in or into Switzerland within the meaning of the Swiss Financial Services Act ("FinSA") and these securities will not be listed or admitted to trading on the SIX Swiss Exchange or on any other regulated trading venue (exchange or multilateral trading facility) in Switzerland. Neither this press release nor any other offering or marketing material relating to these securities, such as the ordinary shares, constitutes or will constitute a prospectus pursuant to the FinSA, and neither this press release nor any other offering or marketing material relating to these securities, such as the ordinary shares, may be publicly distributed or otherwise made publicly available in Switzerland. About SOPHiA GENETICS SOPHiA GENETICS (Nasdaq: SOPH) is a cloud-native healthcare technology company on a mission to expand access to data-driven medicine by using Ai to deliver world-class care to patients with cancer and rare disorders across the globe. It is the creator of SOPHiA DDM(TM), a platform that analyzes complex genomic and multimodal data and generates real-time, actionable insights for a broad global network of hospital, laboratory, and biopharma institutions. Forward-Looking Statements This press release contains forward-looking statements within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, including statements regarding our expectations regarding the expected closing of this offering. In some cases, you can identify forward-looking statements by terminology such as "may", "will", "should", "would", "expect", "intend", "plan", "anticipate", "believe", "estimate", "predict", "potential", "seem", "seek", "future", "continue", or "appear" or the negative of these terms or similar expressions, although not all forward-looking statements contain these identifying words. Forward-looking statements are based on our management's beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the SEC. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (express or implied) are made about the accuracy of any such forward-looking statements. SOURCE SOPHiA GENETICS

Investing.com
Jun 17th, 2026
SOPHiA GENETICS prices $50M public offering at $4.75 per share

SOPHiA GENETICS has priced an underwritten public offering of 10.5 million ordinary shares at $4.75 per share, expecting to raise approximately $50 million in gross proceeds before fees and expenses. The company has granted underwriters a 30-day option to purchase up to 1.6 million additional shares. TD Cowen serves as lead book-running manager, with Guggenheim Securities as book-running manager and BTIG and Craig-Hallum as lead managers. The offering is being conducted through a registration statement filed with the SEC, which was declared effective in August 2025. The transaction is expected to close on Thursday, subject to customary conditions. SOPHiA GENETICS operates as a healthcare technology company specialising in genomic data analysis for hospitals, laboratories and biopharma institutions.

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