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START Center for Cancer Research

Phase 1 cancer trials with genomic profiling

Overview

START Center for Cancer Research runs Phase 1 clinical trials for novel anti-cancer therapies through a network of research sites in the United States, Spain, Portugal, and Ireland. It connects patients with early-stage trials, supported by genetic tumor profiling, multi-disciplinary care, and state-of-the-art treatment technology, to test new drugs before they reach broader use. The center distinguishes itself by its large, community-based trial network with 40+ principal investigators and a track record of conducting over 1,500 early-phase trials, including 50 therapies that later gained FDA/EMA approval. Its goal is to speed the translation of clinical research into available treatments and to expand access to innovative options for patients and physicians worldwide.

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About START Center for Cancer Research

Simplify's Rating
Why START Center for Cancer Research is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Company Size

11-50

Company Stage

N/A

Total Funding

N/A

Headquarters

San Antonio, TX

Founded

N/A

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What believers are saying

  • START opened its first Italy site on November 3, 2026, unlocking a major market.
  • Baptist Health and AHN partnerships in 2026 expand access across Florida and Pennsylvania.
  • Moderna's May 2025 first-U.S. dose at START San Antonio validates sponsor confidence.

What critics are saying

  • START depends on hospital partners like Baptist, AHN, and IFO for site growth.
  • Large pharma can shift phase 1 studies to CROs with broader global infrastructure.
  • If sponsor demand slows, START's fixed-site model and investigator payroll create existential cash strain.

What makes START Center for Cancer Research unique

  • START runs community-based phase 1 oncology sites inside trusted regional cancer systems.
  • Its 2026 Italy, Pittsburgh, and South Florida partnerships extend a rare multinational network.
  • XenoSTART links patient-derived xenografts to clinical sites, strengthening translational drug-development capabilities.

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Benefits

  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • Life Insurance
  • Disability Insurance
  • Health Savings Account/Flexible Spending Account
  • Unlimited Paid Time Off
  • Meal Benefits
  • Commuter Benefits
  • Childcare Support
  • 401(k) Company Match
  • Performance Bonus

Company News

PR Newswire
Nov 3rd, 2026
START opens first Italian early-phase cancer trial site in Rome with Regina Elena institute

The START Center for Cancer Research, the largest global network of dedicated early-phase oncology trial sites, is opening its first Italian site in Rome. It will partner with Istituti Fisioterapici Ospitalieri (IFO), a public research hospital organisation, to set up the site inside the Regina Elena National Cancer Institute. The site aims to give patients in Rome, the Lazio region, and across Italy access to experimental cancer therapies. Italy records about 390,000 new cancer diagnoses a year, yet runs fewer clinical trials relative to its population than several major Western European markets. The new site will be fully integrated into START's network, which has more than 45 principal investigators across 17 locations in the US and Europe, and nearly 1,000 active studies. "We can bring early-phase oncology research closer to patients across Italy," said Nick Slack, START's chairman and chief executive officer.

PR Newswire
Aug 25th, 2026
AHN and START launch cancer trial site to expand patient access in Western Pennsylvania

Allegheny Health Network and The START Center for Cancer Research have formed a strategic collaboration to expand access to early-phase cancer trials in western Pennsylvania. A new START clinical trial site will be established within AHN Cancer Center at Allegheny General Hospital in Pittsburgh. Western Pennsylvania sees approximately 89,000 new cancer cases diagnosed annually across the state, yet patients have historically faced limited local access to early-phase oncology trials. The collaboration will integrate START's expertise in community-based oncology trials with AHN's network of cancer specialists. START operates the largest global network of early-phase clinical trial sites, with over 40 principal investigators across 16 locations in the United States and Europe. The network maintains nearly 1,000 active studies. AHN Cancer Center serves over 20,000 new patients annually across 24 affiliated oncology clinics.

Clinical Research News
Jun 1st, 2026
Baptist Health South Florida and The START Center for Cancer Research announce strategic partnership to expand patient access to early-phase cancer trials.

Baptist Health South Florida and The START Center for Cancer Research announce strategic partnership to expand patient access to early-phase cancer trials. Jun 1, 2026, 09:50 AM by New START site to be established in collaboration with Baptist Health Herbert Wertheim Cancer Institute will bring novel oncology therapies closer to patients across South Florida. Baptist Health South Florida and The START Center for Cancer Research, the largest global network of fully dedicated, early-phase oncology clinical trial sites, today announced plans to form a strategic collaboration. A new START early-phase clinical trial site will be established in collaboration with Herbert Wertheim Cancer Institute, part of Baptist Health South Florida, giving patients across South Florida direct access to the most advanced investigational cancer therapies in the world. South Florida represents a significant and growing need for expanded access to early-phase oncology clinical trials. With more than 130,000 new cancer cases diagnosed annually across Florida, patients in the region have historically had limited local access to early-phase studies, often requiring travel outside their communities to participate. This partnership is designed to bring those opportunities closer to where patients live and receive care. The partnership brings together START's expertise conducting early-phase, oncology trials and Baptist Health's network of nationally recognized cancer specialists, anchored by Herbert Wertheim Cancer Institute and Lynn Cancer Institute. Patients across Baptist Health's system, as well as patients across the region will have access to investigational therapies close to home. "START's mission is to bring the hope of early-phase clinical trials to every community." said Nick Slack, MBE, Chairman and CEO of START. "South Florida is home to millions of people who deserve access to the best cancer research in the world. Most cancer patients are treated in community settings and START exists to make sure those patients have access to early-phase clinical trial options. Baptist Health brings not only the scale and trust of its community, but also a vibrant culture of research that makes this partnership especially powerful. Together, we are expanding access to novel therapies and advancing our mission of Hope Through Access." "Partnering with START gives patients and physicians access to first-in-class oncology trials that would otherwise require traveling hundreds of miles. For a community as large and diverse as ours, that matters enormously," said Leonard Kalman, M.D., acting system chief executive of Baptist Health Cancer Care and acting executive medical director of Baptist Health Herbert Wertheim Cancer Institute. "We look forward to what we will accomplish together for patients across south Florida." Baptist Health is the region's largest not-for-profit health care organization, with 12 hospitals, more than 29,000 employees and more than 200 outpatient facilities across Miami-Dade, Broward, Palm Beach and Martin counties. START operates the largest global network of early-phase clinical trial sites, with more than 40 world-class Principal Investigators across 15 locations in the United States and Europe. With nearly 1,000 active studies, START provides access to one of the most extensive portfolios of industry-sponsored early-phase cancer trials worldwide. The new Baptist Health site will be fully integrated into the START network, with access to its global trial portfolio from day one. About START Deeply rooted in community oncology centers globally, The START Center for Cancer Research provides access to specialized preclinical and early-phase clinical trials of novel anti-cancer agents. START clinical trial sites have conducted more than 1,000 early-phase clinical trials, including for 50 therapies that were approved by the FDA or EMA. START represents the world's largest roster of early-phase principal investigators across its 15 clinical trial sites. Committed to accelerating passage from trials to treatments, START delivers hope to patients, families, and physicians around the world. Learn more at STARTresearch.com. About Baptist Health South Florida Baptist Health South Florida is the largest healthcare organization in the region, with 12 hospitals, more than 29,000 employees, 4,500 physicians and 200 outpatient centers, urgent care facilities and physician practices spanning Miami-Dade, Monroe, Broward and Palm Beach counties. Baptist Health has internationally renowned institutes specializing in cancer care, brain and spine care, heart and vascular care and orthopedic care. In addition, it includes Baptist Health Medical Group; Baptist Health Quality Network; and the Baptist Health PineApp, a virtual health platform. Baptist Health South Florida is an academic and clinical affiliate of Florida International University. A not-for-profit organization supported by philanthropy and committed to its charitable mission of medical excellence, Baptist Health has been recognized by Fortune as one of the 100 Best Companies to Work For in America and is the most awarded healthcare system in South Florida by U.S. News & World Report. For more information, visit BaptistHealth.net/Newsroom and connect with Clinicalresearchnewsonline on Facebook, X (formerly Twitter), Instagram, TikTok and LinkedIn.

PR Newswire
May 28th, 2026
Baptist Health South Florida partners with START to expand early-phase cancer trial access across the region

Baptist Health South Florida and The START Center for Cancer Research have announced a strategic partnership to establish a new early-phase clinical trial site in collaboration with Herbert Wertheim Cancer Institute. The initiative aims to expand access to investigational cancer therapies for patients across South Florida. Florida records over 130,000 new cancer cases annually, yet patients have historically faced limited local access to early-phase trials. The partnership combines START's expertise in conducting early-phase oncology trials with Baptist Health's network of cancer specialists. START operates the largest global network of early-phase clinical trial sites, with more than 40 principal investigators across 15 locations in the US and Europe. The new site will integrate into START's network immediately, providing access to nearly 1,000 active studies from day one.

PR Newswire
Apr 30th, 2026
START appoints Dr Neel Belani as clinical investigator at New Jersey site

START Center for Cancer Research has appointed Neel Belani, MD, MBA, as Clinical Investigator at its New Jersey site. Dr Belani will conduct early-phase oncology trials and expand patient access to clinical studies in the region. Dr Belani is a board-certified medical oncologist specialising in thoracic oncology and early-phase research. He previously served as Principal Investigator on multiple trials and Sub-Investigator on over 200 Phase 1 studies. He completed his fellowship at Fox Chase Cancer Center and holds degrees from Rutgers. START New Jersey operates through a collaboration with Astera Cancer Care, serving an addressable population of 10 million with approximately 150,000 new cancer cases annually. The appointment strengthens START's global network of community-based research sites focused on accelerating oncology drug development.

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