START Center for Cancer Research

START Center for Cancer Research

Phase 1 cancer trials with genomic profiling

Overview

START Center for Cancer Research runs Phase 1 clinical trials for novel anti-cancer therapies through a network of research sites in the United States, Spain, Portugal, and Ireland. It connects patients with early-stage trials, supported by genetic tumor profiling, multi-disciplinary care, and state-of-the-art treatment technology, to test new drugs before they reach broader use. The center distinguishes itself by its large, community-based trial network with 40+ principal investigators and a track record of conducting over 1,500 early-phase trials, including 50 therapies that later gained FDA/EMA approval. Its goal is to speed the translation of clinical research into available treatments and to expand access to innovative options for patients and physicians worldwide.

About START Center for Cancer Research

Simplify's Rating
Why START Center for Cancer Research is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Company Size

11-50

Company Stage

N/A

Total Funding

N/A

Headquarters

San Antonio, Texas

Founded

N/A

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Simplify's Take

What believers are saying

  • Baptist Health partnership added a South Florida site in May 2026.
  • START dosed Moderna's first U.S. patient for mRNA-4106 at San Antonio in May 2025.
  • Dr. Neel Belani joined START New Jersey in April 2026, strengthening thoracic enrollment.

What critics are saying

  • START depends on sponsor-funded early-phase assets; Moderna's mRNA-4106 remains unproven in humans.
  • OneOncology and Baptist can renegotiate site economics, squeezing START margins during 2026 expansions.
  • If sponsors shift to centralized academic centers, START's community model loses differentiation entirely.

What makes START Center for Cancer Research unique

  • START runs 15 sites across the United States and Europe, focused on early-phase oncology.
  • Its network has supported over 1,000 early-phase trials and 50 FDA or EMA approvals.
  • XenoSTART pairs 2,800 patient-derived xenograft models with clinical trial patient data.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

Health Savings Account/Flexible Spending Account

Unlimited Paid Time Off

Meal Benefits

Commuter Benefits

Childcare Support

401(k) Company Match

Performance Bonus

Paid Holidays

Paid Vacation

Employee Assistance Program

Flexible Work Hours

Company News

Clinical Research News
Jun 1st, 2026
Baptist Health South Florida and The START Center for Cancer Research announce strategic partnership to expand patient access to early-phase cancer trials.

Baptist Health South Florida and The START Center for Cancer Research announce strategic partnership to expand patient access to early-phase cancer trials. Jun 1, 2026, 09:50 AM by New START site to be established in collaboration with Baptist Health Herbert Wertheim Cancer Institute will bring novel oncology therapies closer to patients across South Florida. Baptist Health South Florida and The START Center for Cancer Research, the largest global network of fully dedicated, early-phase oncology clinical trial sites, today announced plans to form a strategic collaboration. A new START early-phase clinical trial site will be established in collaboration with Herbert Wertheim Cancer Institute, part of Baptist Health South Florida, giving patients across South Florida direct access to the most advanced investigational cancer therapies in the world. South Florida represents a significant and growing need for expanded access to early-phase oncology clinical trials. With more than 130,000 new cancer cases diagnosed annually across Florida, patients in the region have historically had limited local access to early-phase studies, often requiring travel outside their communities to participate. This partnership is designed to bring those opportunities closer to where patients live and receive care. The partnership brings together START's expertise conducting early-phase, oncology trials and Baptist Health's network of nationally recognized cancer specialists, anchored by Herbert Wertheim Cancer Institute and Lynn Cancer Institute. Patients across Baptist Health's system, as well as patients across the region will have access to investigational therapies close to home. "START's mission is to bring the hope of early-phase clinical trials to every community." said Nick Slack, MBE, Chairman and CEO of START. "South Florida is home to millions of people who deserve access to the best cancer research in the world. Most cancer patients are treated in community settings and START exists to make sure those patients have access to early-phase clinical trial options. Baptist Health brings not only the scale and trust of its community, but also a vibrant culture of research that makes this partnership especially powerful. Together, we are expanding access to novel therapies and advancing our mission of Hope Through Access." "Partnering with START gives patients and physicians access to first-in-class oncology trials that would otherwise require traveling hundreds of miles. For a community as large and diverse as ours, that matters enormously," said Leonard Kalman, M.D., acting system chief executive of Baptist Health Cancer Care and acting executive medical director of Baptist Health Herbert Wertheim Cancer Institute. "We look forward to what we will accomplish together for patients across south Florida." Baptist Health is the region's largest not-for-profit health care organization, with 12 hospitals, more than 29,000 employees and more than 200 outpatient facilities across Miami-Dade, Broward, Palm Beach and Martin counties. START operates the largest global network of early-phase clinical trial sites, with more than 40 world-class Principal Investigators across 15 locations in the United States and Europe. With nearly 1,000 active studies, START provides access to one of the most extensive portfolios of industry-sponsored early-phase cancer trials worldwide. The new Baptist Health site will be fully integrated into the START network, with access to its global trial portfolio from day one. About START Deeply rooted in community oncology centers globally, The START Center for Cancer Research provides access to specialized preclinical and early-phase clinical trials of novel anti-cancer agents. START clinical trial sites have conducted more than 1,000 early-phase clinical trials, including for 50 therapies that were approved by the FDA or EMA. START represents the world's largest roster of early-phase principal investigators across its 15 clinical trial sites. Committed to accelerating passage from trials to treatments, START delivers hope to patients, families, and physicians around the world. Learn more at STARTresearch.com. About Baptist Health South Florida Baptist Health South Florida is the largest healthcare organization in the region, with 12 hospitals, more than 29,000 employees, 4,500 physicians and 200 outpatient centers, urgent care facilities and physician practices spanning Miami-Dade, Monroe, Broward and Palm Beach counties. Baptist Health has internationally renowned institutes specializing in cancer care, brain and spine care, heart and vascular care and orthopedic care. In addition, it includes Baptist Health Medical Group; Baptist Health Quality Network; and the Baptist Health PineApp, a virtual health platform. Baptist Health South Florida is an academic and clinical affiliate of Florida International University. A not-for-profit organization supported by philanthropy and committed to its charitable mission of medical excellence, Baptist Health has been recognized by Fortune as one of the 100 Best Companies to Work For in America and is the most awarded healthcare system in South Florida by U.S. News & World Report. For more information, visit BaptistHealth.net/Newsroom and connect with Clinicalresearchnewsonline on Facebook, X (formerly Twitter), Instagram, TikTok and LinkedIn.

PR Newswire
May 28th, 2026
Baptist Health South Florida partners with START to expand early-phase cancer trial access across the region

Baptist Health South Florida and The START Center for Cancer Research have announced a strategic partnership to establish a new early-phase clinical trial site in collaboration with Herbert Wertheim Cancer Institute. The initiative aims to expand access to investigational cancer therapies for patients across South Florida. Florida records over 130,000 new cancer cases annually, yet patients have historically faced limited local access to early-phase trials. The partnership combines START's expertise in conducting early-phase oncology trials with Baptist Health's network of cancer specialists. START operates the largest global network of early-phase clinical trial sites, with more than 40 principal investigators across 15 locations in the US and Europe. The new site will integrate into START's network immediately, providing access to nearly 1,000 active studies from day one.

PR Newswire
Apr 30th, 2026
START appoints Dr Neel Belani as clinical investigator at New Jersey site

START Center for Cancer Research has appointed Neel Belani, MD, MBA, as Clinical Investigator at its New Jersey site. Dr Belani will conduct early-phase oncology trials and expand patient access to clinical studies in the region. Dr Belani is a board-certified medical oncologist specialising in thoracic oncology and early-phase research. He previously served as Principal Investigator on multiple trials and Sub-Investigator on over 200 Phase 1 studies. He completed his fellowship at Fox Chase Cancer Center and holds degrees from Rutgers. START New Jersey operates through a collaboration with Astera Cancer Care, serving an addressable population of 10 million with approximately 150,000 new cancer cases annually. The appointment strengthens START's global network of community-based research sites focused on accelerating oncology drug development.

Woodburn Independent
Apr 30th, 2026
START research expands clinical leadership with appointment of Dr. Neel Belani as Clinical Investigator at START New Jersey.

START research expands clinical leadership with appointment of Dr. Neel Belani as Clinical Investigator at START New Jersey. PR Newswire Today at 5:01am PDT Strengthening clinical research capabilities in one of the nation's most densely populated and high-opportunity oncology markets EAST BRUNSWICK, N.J., April 30, 2026 /PRNewswire/ - The START Center for Cancer Research ("START"), the world's largest community-based network of clinical trial sites specializing in early-phase oncology trials, today announced the appointment of Neel Belani, MD, MBA, as Clinical Investigator at START New Jersey. In this role, Dr. Belani will conduct leading clinical trials and further expand access to early-phase oncology studies for patients across the region, returning to his home state of New Jersey where he began his medical training. Dr. Belani joins START through its collaboration with Astera Cancer Care, a leading oncology practice and partner within the OneOncology network. START New Jersey is strategically positioned to serve a large and diverse patient population, with an estimated 10 million addressable population, approximately 150,000 new cancer cases annually, and more than 12,000 new patients within the partner practice each year, providing a strong foundation for early-phase clinical trial access and enrollment. "Dr. Belani represents the next generation of clinical research leadership - bringing both deep scientific expertise and a strong commitment to patient-centered care," said Nick Slack, MBE, Chief Executive Officer of START. "His experience in early-phase trials, combined with his track record of high-quality trial execution and patient care, strengthens our ability to deliver high-quality studies and accelerate access to innovative therapies for patients." Dr. Belani is a board-certified medical oncologist with a strong focus on thoracic oncology and early-phase clinical research. Prior to joining START, he was an attending oncologist and clinical investigator, serving as a Principal Investigator on multiple clinical trials and a Sub-Investigator on more than 200 Phase 1 studies. He completed his hematology and oncology fellowship at Fox Chase Cancer Center, Temple University, and his internal medicine residency at Brown University. Dr. Belani earned his MD from Rutgers New Jersey Medical School and holds an MBA from Rutgers Business School, bringing a unique perspective that bridges clinical care, research, and healthcare systems. "I'm excited to join START and be part of a network that is redefining how early-phase oncology research is delivered," said Dr. Belani. "Expanding access to clinical trials in the community setting is critical to ensuring more patients have the opportunity to benefit from innovative therapies, and I look forward to working alongside this team to advance that mission." START New Jersey operates in collaboration with Astera Cancer Care and is supported by a dedicated oncology research team and infrastructure, enabling efficient study start-up and high-quality trial execution. Dr. Belani will work closely with Director of Clinical Research at START New Jersey, Dr. Bruno S. Fang, as well as a multidisciplinary clinical and research team, to expand the site's capabilities and accelerate enrollment in early-phase studies. "Dr. Belani's experience in early-phase clinical trials and his commitment to advancing translational research make him an outstanding addition to our team," said Chris Takimoto, MD, PhD, FACP, Chief Medical Officer of START. "As the complexity of oncology drug development continues to evolve, strong clinical leadership at the site level is essential to ensure we are bringing the right therapies to patients efficiently and safely." With this appointment, START continues to strengthen its global network of community-based research sites, focused on accelerating drug development and expanding access to clinical trials for patients worldwide. About The START Center for Cancer Research Deeply rooted in community oncology centers globally, The START Center for Cancer Research provides access to specialized preclinical and early-phase clinical trials of novel anti-cancer agents. START clinical trial sites have conducted more than 1,000 early-phase clinical trials, including for more than 50 therapies that were approved by the FDA or EMA. START represents the world's largest roster of early-phase principal investigators across its global network of clinical trial sites. Committed to accelerating the development of new cancer therapies, START delivers hope to patients, families, and physicians around the world. Learn more at STARTresearch.com. SOURCE The START Center for Cancer Research This is a paid placement. For further inquiries, please contact PR Newswire directly.

PR Newswire
Apr 9th, 2026
START appoints Dr. Salwan Al Mutar as director of clinical research in Dallas-Fort Worth

The START Center for Cancer Research has appointed Dr Salwan Al Mutar as Director of Clinical Research at its Dallas-Fort Worth location. Dr Al Mutar will lead clinical research operations and support early-phase oncology programme expansion across North Texas. Dr Al Mutar joins from the University of Texas Southwestern Medical Center, where he served as Assistant Professor in Hematology/Oncology and attending physician at the Harold C. Simmons Comprehensive Cancer Center. His expertise spans gastrointestinal malignancies, particularly pancreatic cancer and biomarker-driven therapies. START is the world's largest community-based network of clinical trial sites specialising in early-phase oncology trials. The Dallas-Fort Worth region diagnoses approximately 40,000 new cancer cases annually, providing access to a large patient population for clinical research.

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