Scorpion Therapeutics

Scorpion Therapeutics

Develops precision oncology drugs through partnerships

Overview

Scorpion Therapeutics develops precision oncology drugs that target validated cancer drivers. It designs therapies with high target selectivity and favorable pharmacology, using biology, chemistry, proteomics, and computation, then partners with large pharmaceutical companies to fund and scale development. It differentiates itself through a target-driven science approach and strategic collaborations with milestone and royalty terms. The goal is to deliver fast, precise, and potent cancer treatments and bring them to patients worldwide through partnerships.

About Scorpion Therapeutics

Simplify's Rating
Why Scorpion Therapeutics is rated
C+
Rated C on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

AI & Machine Learning

Biotechnology

Healthcare

Company Size

11-50

Company Stage

Acquired

Total Funding

$2.9B

Headquarters

Boston, Massachusetts

Founded

2020

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Simplify's Take

What believers are saying

  • Eli Lilly acquired STX-478 program for up to $2.5B in January 2025.
  • Pierre Fabre deal grants $618M for EGFR inhibitors in Europe and China.
  • $150M Series C funding advances remaining oncology pipeline.

What critics are saying

  • Lilly controls STX-478 development post-2025 acquisition.
  • STX-478 21-23% ORR trails Relay's RLY-2608 combinations.
  • Pipeline depletion post-STX-478 sale strands early assets.

What makes Scorpion Therapeutics unique

  • STX-478 selectively inhibits mutant PI3Kα kinase and helical mutations.
  • STX-478 demonstrates 23% ORR in breast cancer monotherapy.
  • Pfizer collaboration evaluates STX-478 triplet in frontline breast cancer.

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Funding

Total Funding

$2.9B

Above

Industry Average

Funded Over

4 Rounds

Notable Investors:
Acquisition funding comparison data is currently unavailable. We're working to provide this information soon!
Acquisition Funding Comparison
Coming Soon

Growth & Insights and Company News

Headcount

6 month growth

-5%

1 year growth

-36%

2 year growth

0%
Business Wire
Jun 11th, 2025
Antares Therapeutics Launches with $177 Million to Develop First-in-Class Precision Medicines for Cancer and Other Serious Diseases

Antares Therapeutics, Inc. (“Antares”), a biotechnology company developing first-in-class precision medicines for cancer and other serious diseases, launched...

GlobalData
Jul 17th, 2024
Scorpion Therapeutics secures $150m for oncology pipeline

In conjunction with the funding, Lightspeed Venture partner Shelley Chu will become an investor board member and Frazier Life Sciences managing partner Albert Cha will join the board of Scorpion as an observer.

FinSMEs
Jul 16th, 2024
Scorpion Therapeutics Raises $150M in Series C Financing

Scorpion Therapeutics, a Boston, MA-based clinical-stage oncology company, raised $150M in Series C funding

Business Wire
Jan 4th, 2024
Scorpion Therapeutics Appoints Adam Friedman, M.D., Ph.D., as Chief Executive Officer and Expands Leadership Team

Scorpion Therapeutics appoints Adam Friedman, M.D., Ph.D., as Chief Executive Officer and expands Leadership Team.

Fierce Biotech
Jan 4th, 2024
Scorpion's CEO Axel Hoos, CMO bite the dust as oncology biotech brings in new leadership

Streit joined Scorpion in 2022 from Sanofi, where he had most recently served as vice president and senior project head.

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