Scorpion Therapeutics

Scorpion Therapeutics

Develops precision oncology drugs through partnerships

Overview

Scorpion Therapeutics develops precision oncology drugs that target validated cancer drivers. It designs therapies with high target selectivity and favorable pharmacology, using biology, chemistry, proteomics, and computation, then partners with large pharmaceutical companies to fund and scale development. It differentiates itself through a target-driven science approach and strategic collaborations with milestone and royalty terms. The goal is to deliver fast, precise, and potent cancer treatments and bring them to patients worldwide through partnerships.

About Scorpion Therapeutics

Simplify's Rating
Why Scorpion Therapeutics is rated
C+
Rated B on Competitive Edge
Rated C on Growth Potential
Rated C on Differentiation

Industries

AI & Machine Learning

Biotechnology

Healthcare

Company Size

11-50

Company Stage

Acquired

Total Funding

$420M

Headquarters

Boston, Massachusetts

Founded

2020

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Simplify's Take

What believers are saying

  • Lilly's $2.5 billion deal validated STX-478 and Scorpion's medicinal chemistry.
  • Antares launched with $177 million, preserving Scorpion's team and discovery engine.
  • Pierre Fabre and AstraZeneca collaborations showed repeatable partnership value beyond one asset.

What critics are saying

  • Scorpion ceased as an independent company after Lilly's 2025 acquisition announcement.
  • The remaining spinout, Antares, depends on early preclinical programs entering clinic in 2026.
  • PI3K inhibitors have a mixed history; STX-478 must outperform entrenched toxicity and efficacy limits.

What makes Scorpion Therapeutics unique

  • Scorpion built mutant-selective PI3Kα chemistry, culminating in STX-478 for breast cancer.
  • Its platform combines chemical proteomics, machine learning, and precision oncology target selection.
  • Lilly kept Scorpion's core asset, validating the team's drug-discovery capabilities.

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Funding

Total Funding

$420M

Above

Industry Average

Funded Over

4 Rounds

Notable Investors:
Acquisition funding comparison data is currently unavailable. We're working to provide this information soon!
Acquisition Funding Comparison
Coming Soon

Growth & Insights and Company News

Headcount

6 month growth

↑ 6%

1 year growth

↓ -11%

2 year growth

↑ 6%
Eli Lilly and Company
May 5th, 2026
Lilly to acquire Scorpion Therapeutics' mutant-selective PI3Kα inhibitor program | Eli Lilly and Company

The Investor Relations website contains information about Eli Lilly and Company's business for stockholders, potential investors, and financial analysts.

Business Wire
Jun 11th, 2025
Antares Therapeutics Launches with $177 Million to Develop First-in-Class Precision Medicines for Cancer and Other Serious Diseases

Antares Therapeutics, Inc. (“Antares”), a biotechnology company developing first-in-class precision medicines for cancer and other serious diseases, launched...

Pharmaceutical Technology
Jul 17th, 2024
Scorpion Therapeutics secures $150m for oncology pipeline

In conjunction with the funding, Lightspeed Venture partner Shelley Chu will become an investor board member and Frazier Life Sciences managing partner Albert Cha will join the board of Scorpion as an observer.

FinSMEs
Jul 16th, 2024
Scorpion Therapeutics Raises $150M in Series C Financing

Scorpion Therapeutics, a Boston, MA-based clinical-stage oncology company, raised $150M in Series C funding

Business Wire
Jan 4th, 2024
Scorpion Therapeutics Appoints Adam Friedman, M.D., Ph.D., as Chief Executive Officer and Expands Leadership Team

Scorpion Therapeutics appoints Adam Friedman, M.D., Ph.D., as Chief Executive Officer and expands Leadership Team.

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