Seed Health

Seed Health

Develops and sells probiotic microbiome products

Overview

Seed Health develops and sells probiotic and microbiome-based consumer products for humans and pets through its online store. Formulations are grounded in scientific research, tested for safety and effectiveness, and shipped directly to customers. The company differentiates itself by pairing rigorous science with education and transparent communication, while pursuing a direct-to-consumer model and a broader focus on planetary health. Its goal is to improve human and planetary health by making microbiome science actionable and accessible for everyday wellness.

About Seed Health

Simplify's Rating
Why Seed Health is rated
B
Rated B on Competitive Edge
Rated A on Growth Potential
Rated C on Differentiation

Industries

Biotechnology

Education

Healthcare

Consumer Goods

Company Size

201-500

Company Stage

Series A

Total Funding

$40M

Headquarters

Los Angeles, California

Founded

2016

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Simplify's Take

What believers are saying

  • 500% revenue growth past three years; top-five Amazon probiotic and Target fastest-growing brand.
  • Expanded omnichannel distribution to Target, Amazon, and Sprouts nationwide by September 2024.
  • Clinical pipeline expansion: DS-01® efficacy in antibiotic recovery, IBS, and metabolic health demonstrated.

What critics are saying

  • FDA enforcement actions on unapproved health claims for DS-01® and VS-01® within 12 months.
  • Pendulum Therapeutics' GLP-1 mimicking probiotic directly competes on butyrate pathways with superior data.
  • Resilient Soils Project fails to yield patentable PFAS-degrading microbes; SeedLabs funding halted.

What makes Seed Health unique

  • DS-01® clinically proven to increase Urolithin A production 100-fold by Day 7.
  • Multi-strain synbiotics validated through double-blind, placebo-controlled trials at academic institutions.
  • Proprietary microbial genomics and whole-genome sequencing for strain validation and quality assurance.

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Funding

Total Funding

$40M

Above

Industry Average

Funded Over

1 Rounds

Notable Investors:
Series A funding typically happens when a startup has a product and some customers, and now needs funding to scale. This money is usually used to grow the team, expand marketing, and improve the product. Venture capital firms are frequently the main investors here.
Series A Funding Comparison
Above Average

Industry standards

$15M
$8.2M
Discord
$15M
Canva
$30M
Kalshi
$40M
Seed Health

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

401(k) Company Match

Mental Health Support

Wellness Program

Remote Work Options

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

-1%

2 year growth

1%
PR Newswire
May 5th, 2025
Seed Health Presents New Clinical Trial Data: Ds-01® Increases Two Key Microbiome Molecules Linked To Gut, Metabolic, Immune, And Cellular Health

DS-01® is the first broad-spectrum synbiotic clinically shown to increase production of both Urolithin A and butyrate—two key microbial metabolites linked to whole-body healthPresented at Digestive Disease Week® (DDW) 2025, the findings expand DS-01®'s clinical foundation and reinforce the potential of microbiome-targeted products to impact multiple biological systemsBOSTON, May 5, 2025 /PRNewswire/ -- Microbiome science company Seed Health presented clinical data on its flagship innovation, DS-01® Daily Synbiotic, at Digestive Disease Week® (DDW) 2025. Findings from a randomized, placebo-controlled clinical trial in healthy adults demonstrated that DS-01® increased production of two key microbial metabolites—Urolithin A and butyrate—implicated in gut barrier function, metabolism, and healthy aging. The trial also found reductions in C-Reactive Protein (CRP), a widely used marker of systemic inflammation, suggesting DS-01®'s potential to influence immune pathways. The findings underscore DS-01®'s impact beyond microbial composition, demonstrating measurable biological function through the production of microbiome-mediated metabolites.The company presented two posters during the "Prebiotics, Probiotics and Synbiotics in Health and Disease" session.Presentation HighlightsEffects of a novel, broad-spectrum synbiotic on Urolithin A production: A randomized, placebo-controlled clinical trialThis randomized, placebo-controlled clinical trial evaluated DS-01® for its ability to increase production of Urolithin A—a microbiome-derived metabolite linked to mitochondrial function, cellular energy, metabolic health, intestinal barrier integrity, and healthy aging. DS-01® provides the natural machinery to produce Urolithin A, delivering both a polyphenol precursor in its prebiotic outer capsule and key microbes in its probiotic inner capsule.Overall, this is the first study to demonstrate that a broad-spectrum synbiotic can increase Urolithin A production in humans. Key findings include:Rapid and Sustained Urolithin A Increase: DS-01® increased urinary Urolithin A levels by approximately 100-fold by Day 7 (P<0.0001), with levels sustained through Day 91.DS-01® increased urinary Urolithin A levels by approximately 100-fold by Day 7 (P<0.0001), with levels sustained through Day 91

The Chalkboard Mag
Aug 8th, 2024
I Tried Seed Health's New Vaginal Probiotic-Here's Why You Should Too

(In fact, one of its editors previously covered the Daily Synbiotic at The Chalkboard Mag) But it wasn't until Seed Health launched its VS-01(TM) Vaginal Synbiotic that I decided to give the brand a try to rebalance my microbiome and the rest of my system.

PR Newswire
Aug 1st, 2024
New Clinical Data Highlights Efficacy Of Seed Health'S Vs-01 Vaginal Synbiotic In Establishing Protective And Optimal Vaginal Microbiome

The study, which is the first to show that a multi-strain vaginal synbiotic can establish a protective vaginal environment, will be presented at the Annual Meeting of the Infectious Diseases Society for Obstetrics and Gynecology (IDSOG)The data demonstrate that VS-01™ successfully cultivates a vaginal microbiome dominated by Lactobacillus crispatus, reduces harmful microbes, and combats vaginal dysbiosisThese results underscore the potential of the vaginal microbiome and microbiome-directed innovations to redefine standards of care in women's healthBOSTON, Aug. 1, 2024 /PRNewswire/ -- Seed Health will present new clinical data on its flagship vaginal microbiome innovation, VS-01™ Vaginal Synbiotic, at the upcoming 2024 Infectious Diseases Society for Obstetrics and Gynecology (IDSOG) Annual Meeting. Data from a randomized, placebo-controlled clinical trial demonstrated the superior efficacy of VS-01™ in cultivating a stable and healthy vaginal microbiome. The synbiotic successfully established a protective environment dominated by Lactobacillus crispatus and inhibited harmful microbes associated with vaginal dysbiosis and inflammation. These findings highlight the transformative potential of proactive, preventive care centered on the vaginal microbiome, shifting the focus from traditional symptom management to maintaining a balanced and resilient vaginal ecology.A landmark 2012 study from vaginal microbiome researcher Jacques Ravel, Ph.D., demonstrated that the most stable and optimal vaginal microbiome is characterized by a dominance of the bacterium Lactobacillus crispatus, which plays a protective role in maintaining vaginal health. However, everyday factors such as menstruation, sexual activity, exercise, stress, contraceptives, and cleansers can deplete the abundance of L

Forbes
May 23rd, 2024
LA-Based Probiotic Company Hones In On Vaginal Health

LA-based probiotic company Seed is launching a new vaginal suppository that will help women maintain a more stable vaginal microbiome.

PR Newswire
May 21st, 2024
Seed Health Launches Vs-01, A First-Of-Its Kind Vaginal Microbiome Innovation To Redefine Vaginal Care

An optimal vaginal microbiome is a key driver of gynecological, urogenital, and reproductive healthVS-01™ is a multi-strain probiotic and prebiotic clinically validated to establish an optimal vaginal microbiome and sustain regulated vaginal pHBuilt on the research of renowned vaginal microbiome scientist Dr. Jacques Ravel, VS-01™ is the first to pioneer a microbial genomics approach powered by the most comprehensive host-microbiome vaginal data setLOS ANGELES, May 21, 2024 /PRNewswire/ -- Seed Health , a microbiome science company, today launched VS-01™ Vaginal Synbiotic, the first vaginal synbiotic clinically validated to rapidly establish an optimal vaginal microbiome dominated by Lactobacillus crispatus, the vagina's most protective bacteria. Dr. Jacques Ravel's pioneering research has elucidated the crucial role of the vaginal microbiome in gynecological, urogenital, and reproductive health, though everyday factors like stress, sex, menstruation, and diet can disrupt its equilibrium and deplete the abundance of L. crispatus. Dr

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