Shape Therapeutics

Shape Therapeutics

Develops programmable RNA medicines using AI

About Shape Therapeutics

Simplify's Rating
Why Shape Therapeutics is rated
B+
Rated B on Competitive Edge
Rated B on Growth Potential
Rated A on Differentiation

Industries

AI & Machine Learning

Biotechnology

Company Size

51-200

Company Stage

Series B

Total Funding

$147.5M

Headquarters

Seattle, Washington

Founded

2018

Overview

Shape Therapeutics focuses on programmable RNA medicine, utilizing artificial intelligence to analyze extensive datasets for developing new treatments. Their primary product involves designing novel RNAs that can reprogram cells to address diseases by correcting mutations and adjusting gene expression. A standout feature of their technology is RNAfix, which employs a natural enzyme to modify RNA instructions without altering DNA, allowing for the correction of genetic disorders. Additionally, ShapeTX employs smart-sensing vector designs to customize gene expression for specific cell types, enhancing treatment options beyond traditional methods. The company distinguishes itself from competitors by integrating AI with RNA technology to create medicines that are not only effective and safe but also easy to manufacture. The ultimate goal of Shape Therapeutics is to unlock the therapeutic potential of RNA to tackle the root causes of various diseases.

📈
Significant Headcount Growth
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Simplify's Take

What believers are saying

  • Increased interest in RNA therapies boosts ShapeTX's market potential.
  • AI integration in drug discovery enhances ShapeTX's innovative capabilities.
  • FDA fast-tracking of RNA therapies supports ShapeTX's regulatory pathway.

What critics are saying

  • Intellectual property disputes may arise in the competitive RNA therapy field.
  • Regulatory challenges due to rapid AI and RNA advancements could impact ShapeTX.
  • Talent war in biotech may lead to recruitment challenges for ShapeTX.

What makes Shape Therapeutics unique

  • ShapeTX uses AI to design novel RNAs for precise gene therapy.
  • Their RNAfix technology corrects RNA without altering DNA, offering unique therapeutic potential.
  • Smart-sensing vector designs enable tailored gene expression, surpassing first-generation gene therapies.

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Funding

Total Funding

$147.5M

Above

Industry Average

Funded Over

2 Rounds

Notable Investors:
Series B funding is typically for startups that have proven their business model and need more funding to expand rapidly—often by entering new markets or adding more products. Investors are usually venture capital firms that specialize in later-stage investments.
Series B Funding Comparison
Above Average

Industry standards

$35M
$45M
Linktree
$65M
Substack
$100M
ClickUp
$112M
Shape Therapeutics

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Paid Holidays

Parental Leave

Unlimited Paid Time Off

Disability Insurance

401(k) Retirement Plan

Life Insurance

Health Savings Account/Flexible Spending Account

Growth & Insights and Company News

Headcount

6 month growth

5%

1 year growth

10%

2 year growth

12%
Pharma Focus America
Oct 4th, 2024
Shape Therapeutics Unveils Major Advances in AI-Powered Platform for Precision RNA Editing

Shape Therapeutics, a leader in RNA-based gene therapy, today released two preprint manuscripts detailing major technological breakthroughs that underpin the company's therapeutic editing platform RNAfix(R).

GlobeNewswire
Jun 25th, 2024
Shape Therapeutics Appoints Healthcare Industry Leaders David Epstein And Todd Simpson To Its Board Of Directors

SEATTLE, June 25, 2024 (GLOBE NEWSWIRE) -- Shape Therapeutics, Inc. (ShapeTX), a leader at the convergence of AI and RNA editing to revolutionize genomic medicine, announces the appointments of David Epstein, former CEO of Seagen, and Todd Simpson, former CFO of Seagen, to its board of directors. “We are at a pivotal moment where our investment in breakthrough technologies is now yielding industry-leading results. As we prepare to advance our RNA editing therapies to the clinic, we are thrilled to welcome David and Todd to our board," said Francois Vigneault, Ph.D., chief executive officer of ShapeTX. "Their expertise in scaling life sciences companies, from drug development to clinical success and commercialization, will be invaluable.” David Epstein is a highly respected leader in the pharmaceutical and biotech sectors, renowned for steering Seagen towards a pivotal $44.5 billion acquisition by Pfizer. With over 30 years of global experience in drug development, commercialization, and leadership, David has previously served as an executive partner at Flagship Pioneering and as CEO of Novartis Pharmaceuticals, including its Oncology and Molecular Diagnostic units, transforming it into the second-largest oncology division globally

GlobeNewswire
May 2nd, 2024
Shape Therapeutics Announces Appointment Of Matt Valentino As Chief People Officer

SEATTLE, May 02, 2024 (GLOBE NEWSWIRE) -- Shape Therapeutics Inc. (ShapeTX), a leader at the convergence of AI and RNA editing to revolutionize genomic medicine, is pleased to announce the appointment of Matt Valentino as Chief People Officer.Before joining ShapeTX, Matt was at the helm of diverse People teams for notable biotech and technology companies including Calico Labs, Genentech, Pandora, Validant, and DoorDash.“Matt brings extensive experience in leading teams at scientific R&D companies focused on drug development, manufacturing, robotics, and AI/ML applications. As an early team member at Calico Labs, he played a crucial role in scaling the company from 70 to over 300 employees, including the expansion of their Drug Discovery, Computational and Clinical Development teams. While at DoorDash, Matt facilitated growth from 2,000 to over 17,000 global employees. His expertise will be instrumental in guiding ShapeTX through its next growth phase as we continue to innovate at the intersection of technology and biotechnology," said Francois Vigneault, Ph.D., Co-Founder and CEO of ShapeTX. "We are confident in Matt's leadership and excited about the future developments he will drive at ShapeTX." Matt added, "I’m thrilled to join the talented team at ShapeTX, and I am eager to advance our mission of repairing genetic causes of disease with programmable RNA medicines."About ShapeTXShape Therapeutics operates at the convergence of AI and RNA editing to revolutionize genomic medicine

Bakersfield.com
Sep 8th, 2023
Otsuka collaborates with ShapeTX to develop novel AAV gene therapies for ocular diseases

Otsuka collaborates with ShapeTX to develop novel AAV gene therapies for ocular diseases.

GlobeNewswire
Sep 7th, 2023
Otsuka collaborates with ShapeTX to develop novel AAV gene therapies for ocular diseases

Otsuka collaborates with ShapeTX to develop novel AAV gene therapies for ocular diseases.

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