Surrozen

Surrozen

Develops tissue repair therapeutics via Wnt.

Overview

Surrozen is a clinical-stage biotechnology company focused on tissue repair and regeneration by selectively modulating the Wnt signaling pathway. It develops tissue-specific antibodies that engage the body's own repair mechanisms, with ophthalmology as its primary disease area targeting severe eye conditions. The company advances drug candidates through research and development and clinical trials, aiming to commercialize therapies via collaborations with biopharmaceutical partners. Its competitors work on similar regenerative approaches, but Surrozen differentiates itself by its focus on tissue-specific Wnt modulation through engineered antibodies and by concentrating efforts in ophthalmology to address degenerative eye diseases. The overall goal is to provide new therapeutic options that promote tissue healing and restore function in patients suffering from degenerative conditions, ultimately bringing approved therapies to market.

About Surrozen

Simplify's Rating
Why Surrozen is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Biotechnology

Healthcare

Company Size

51-200

Company Stage

IPO

Headquarters

San Francisco, California

Founded

2016

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Simplify's Take

What believers are saying

  • Boehringer paid a $5 million milestone in July 2026 after Phase 1 initiation.
  • Surrozen targets SZN-8141 IND submission by Q3 2026 and DUET enrollment by year-end.
  • The July 2026 PTAB denial weakened Merck’s challenge to Surrozen’s key patent.

What critics are saying

  • SZN-8141 remains preclinical; failure in 2026 IND or Phase 1 ends the pivot.
  • Surrozen’s $50 million ATM and $102 million cash fund heavy dilution.
  • Boehringer, Merck, or a trial setback could collapse a one-platform ophthalmology story.

What makes Surrozen unique

  • Surrozen’s Wnt-selective antibodies target retinal vascular disease, not broad immunology.
  • SZN-8141 and SZN-8143 combine Wnt with VEGF, and IL-6 for differentiation.
  • Boehringer Ingelheim licensed SZN-413, validating Surrozen’s tissue-specific Wnt platform.

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Funding

Total Funding

$525.5M

Above

Industry Average

Funded Over

7 Rounds

Private Placement VC funding comparison data is currently unavailable. We're working to provide this information soon!
Private Placement VC Funding Comparison
Coming Soon

Benefits

Health Insurance

Stock Price

Growth & Insights and Company News

Headcount

6 month growth

1%

1 year growth

1%

2 year growth

4%
MarketBeat
Aug 2nd, 2026
Perceptive Advisors LLC makes new $6.68 million investment in Surrozen, Inc. $SRZN.

Perceptive Advisors LLC makes new $6.68 million investment in Surrozen, Inc. $SRZN. August 2, 2026 Key points. * Perceptive Advisors initiated a $6.68 million position in Surrozen, purchasing 229,393 shares and acquiring approximately 1.98% of the company. Institutional investors collectively own 66.57% of SRZN. * Analyst sentiment is generally positive, with an average "Moderate Buy" rating and a $42 price target; HC Wainwright raised its target to $44, though Weiss Ratings maintained a sell rating. * Surrozen reported a significant quarterly loss of $11.65 per share versus the expected $1.09 loss, despite revenue of $5 million exceeding the $4 million consensus estimate. Insiders sold approximately $7.18 million of stock during the last quarter. * MarketBeat previews the top five stocks to own by September 1st. Perceptive Advisors LLC bought a new stake in Surrozen, Inc. (NASDAQ:SRZN - Free Report) during the first quarter, according to its most recent disclosure with the Securities and Exchange Commission. The institutional investor bought 229,393 shares of the company's stock, valued at approximately $6,682,000. Perceptive Advisors LLC owned approximately 1.98% of Surrozen as of its most recent SEC filing. Several other institutional investors and hedge funds also recently made changes to their positions in SRZN. Millennium Management LLC grew its position in shares of Surrozen by 557.1% during the fourth quarter. Millennium Management LLC now owns 721,266 shares of the company's stock worth $16,301,000 after buying an additional 611,497 shares in the last quarter. Spruce Street Capital LP acquired a new stake in Surrozen in the fourth quarter valued at $9,764,000. Kalehua Capital Management LLC acquired a new stake in Surrozen in the fourth quarter valued at $8,705,000. Braidwell LP boosted its stake in Surrozen by 235.7% during the 4th quarter. Braidwell LP now owns 470,000 shares of the company's stock valued at $10,622,000 after acquiring an additional 330,000 shares during the last quarter. Finally, Balyasny Asset Management L.P. grew its holdings in Surrozen by 169.3% during the 4th quarter. Balyasny Asset Management L.P. now owns 190,489 shares of the company's stock worth $4,305,000 after acquiring an additional 119,757 shares in the last quarter. 66.57% of the stock is currently owned by hedge funds and other institutional investors. Insider buying and selling at Surrozen. In other Surrozen news, VP Yang Li sold 1,584 shares of Surrozen stock in a transaction that occurred on Monday, May 4th. The stock was sold at an average price of $33.33, for a total value of $52,794.72. Following the completion of the transaction, the vice president directly owned 17,216 shares in the company, valued at $573,809.28. The trade was a 8.43% decrease in their ownership of the stock. The sale was disclosed in a legal filing with the SEC, which is available at this link. Also, CEO Craig C. Parker sold 4,524 shares of the company's stock in a transaction that occurred on Monday, May 4th. The shares were sold at an average price of $33.33, for a total value of $150,784.92. Following the transaction, the chief executive officer directly owned 16,553 shares of the company's stock, valued at $551,711.49. This trade represents a 21.46% decrease in their ownership of the stock. The SEC filing for this sale provides additional information. Insiders sold 333,144 shares of company stock worth $7,177,690 in the last quarter. 31.74% of the stock is currently owned by corporate insiders. Analyst Ratings changes. A number of brokerages have recently issued reports on SRZN. TD Cowen started coverage on shares of Surrozen in a research note on Tuesday, April 21st. They issued a "buy" rating on the stock. HC Wainwright reissued a "buy" rating and issued a $44.00 price objective (up from $36.00) on shares of Surrozen in a report on Thursday, May 7th. Weiss Ratings restated a "sell (d-)" rating on shares of Surrozen in a research note on Friday, July 17th. Finally, Zacks Research raised Surrozen from a "strong sell" rating to a "hold" rating in a report on Tuesday, July 28th. One research analyst has rated the stock with a Strong Buy rating, three have issued a Buy rating, one has assigned a Hold rating and one has assigned a Sell rating to the stock. According to data from MarketBeat.com, the stock currently has an average rating of "Moderate Buy" and an average target price of $42.00. Discover more MarketBeat Research Tools Stock Screener Tool Surrozen price performance. SRZN stock opened at $22.21 on Friday. Surrozen, Inc. has a 1-year low of $9.03 and a 1-year high of $35.00. The firm has a fifty day moving average price of $23.23 and a two-hundred day moving average price of $25.27. The firm has a market cap of $257.86 million, a price-to-earnings ratio of -0.59 and a beta of 0.51. Surrozen (NASDAQ:SRZN - Get Free Report) last issued its earnings results on Wednesday, May 6th. The company reported ($11.65) earnings per share for the quarter, missing analysts' consensus estimates of ($1.09) by ($10.56). The business had revenue of $5.00 million for the quarter, compared to the consensus estimate of $4.00 million. As a group, analysts expect that Surrozen, Inc. will post -7.2 EPS for the current fiscal year. Surrozen profile. Surrozen, Inc is a clinical-stage biopharmaceutical company focused on developing novel therapeutic antibodies that target the Wnt signaling pathway for applications in tissue repair, regeneration and oncology. Founded in 2012 and headquartered in South San Francisco, California, the company leverages its proprietary SurroBody platform to design bispecific antibody molecules capable of modulating Wnt receptor activity with enhanced tissue specificity. The SurroBody platform enables the generation of high-affinity, dual-binding antibodies engineered to either activate or inhibit Wnt signaling, a pathway critical to cell proliferation, differentiation and homeostasis. This instant news alert was generated by narrative science technology and financial data from MarketBeat in order to provide readers with the fastest reporting and unbiased coverage. Please send any questions or comments about this story to [email protected]. Before you consider Surrozen, you'll want to hear this. MarketBeat keeps track of Wall Street's top-rated and best performing research analysts and the stocks they recommend to their clients on a daily basis. MarketBeat has identified the five stocks that top analysts are quietly whispering to their clients to buy now before the broader market catches on... and Surrozen wasn't on the list. While Surrozen currently has a Moderate Buy rating among analysts, top-rated analysts believe these five stocks are better buys. With the proliferation of data centers and electric vehicles, the electric grid will only get more strained. Download this report to learn how energy stocks can play a role in your portfolio as the global demand for energy continues to grow.

Yahoo Finance
May 18th, 2026
Surrozen stock soars 296% despite $34M cash burn and 36% revenue drop

Surrozen, a biotech company, held $107 million in cash as of March 2026 with no debt, providing approximately 3.2 years of runway based on its current annual cash burn of $34 million. The company increased its cash burn by 85% over the past year whilst operating revenue fell 36%, raising concerns about its trajectory. Despite these metrics, Surrozen's share price has risen 296% over the last year. The extended cash runway provides time for business development, though the company may need to raise additional capital through debt or equity to fund continued growth and operations beyond its current reserves.

StockTitan
Mar 30th, 2026
Surrozen (NASDAQ: SRZN) sets $50M ATM shelf with TD Cowen.

Surrozen (NASDAQ: SRZN) sets $50M ATM shelf with TD Cowen. Filing Impact Filing Sentiment Rhea-AI filing summary. Surrozen, Inc. filed a prospectus to offer up to $50,000,000 of common stock through an at-the-market sales agreement with TD Securities (USA) LLC (TD Cowen). The company may sell shares from time to time on Nasdaq or other trading markets under the Sales Agreement dated March 23, 2026. The prospectus states an assumed reference price of $25.15 per share (last reported sale price on March 20, 2026) and illustrates that up to 11,762,608 shares could be issued if the full $50,000,000 aggregate amount is sold at that price. Proceeds are intended for working capital and general corporate purposes, and TD Cowen may receive up to 3.0% of gross proceeds as compensation. Insights. Routine at-the-market shelf financing; flexible capital access without guaranteed sales. The filing establishes an at-the-market facility allowing up to $50,000,000 of common stock to be sold through TD Cowen as agent. Sales may occur in negotiated or exchange transactions and TD Cowen will earn up to 3.0% of gross proceeds. The Sales Agreement permits variable timing and pricing tied to market conditions. Key dependencies include market liquidity for SRZN, board decisions on timing and price limits, and shareholder overhang from options and warrants disclosed as of December 31, 2025. Cash-flow treatment and exact issuance pace will depend on future placement notices and market execution. Key figures. ATM capacity: $50,000,000 Reference price: $25.15 Illustrative shares if fully sold: 11,762,608 shares +3 more Key terms. at the market offering, Sales Agreement, net tangible book value (deficit), smaller reporting company Offering details. 03/30/2026 - 06:21 PM Faq. What does Surrozen's $50,000,000 atmshelf mean for SRZN shareholders? It authorizes sales of up to $50,000,000 of common stock through TD Cowen acting as agent. The company may sell shares over time at market prices, affecting share supply and potential dilution depending on sales volume and prices. How will TD Cowen be compensated under the Sales Agreement for SRZN? TD Cowen may receive up to 3.0% of the gross proceeds from any sales of common stock under the Sales Agreement. The prospectus also notes reimbursement of certain legal expenses and estimated offering expenses borne by the company. How many shares could be issued if Surrozen sells the full $50,000,000? Using the reference price of $25.15 per share, the prospectus illustrates issuance of up to 11,762,608 shares. The actual number will vary with sale prices and timing under the Sales Agreement. What will Surrozen use the net proceeds for from this offering? Surrozen intends to use net proceeds for working capital and general corporate purposes, including research and development, administrative expenses, capital expenditures, and potential strategic investments, though no commitments for acquisitions are disclosed. Will this offering immediately dilute new investors in SRZN? The prospectus shows an illustrative dilution of $37.53 per new share based on a $25.15 assumed price and the company's as-adjusted net tangible book deficit figures as of December 31, 2025.

StockTitan
Aug 28th, 2025
Surrozen to Present at Upcoming Healthcare Investor Conference

Surrozen (Nasdaq: SRZN), a biotechnology company focused on developing targeted therapeutics for the Wnt pathway with emphasis on severe eye diseases, has announced its participation in the Cantor Global Healthcare Conference 2025.

StockTitan
Aug 6th, 2025
Surrozen to Present at Upcoming Healthcare Investor Conference

Surrozen (Nasdaq: SRZN), a biotechnology company focused on developing targeted therapeutics that modulate the Wnt pathway for tissue repair and regeneration, particularly in severe eye diseases, has announced its participation in the H.C. Wainwright 5th Annual Ophthalmology Virtual Conference.

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