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System

Causal, data-driven maps of complex systems

Overview

System, Inc. helps people understand and address complex global problems by turning vast data into system maps. It builds data-driven graphical models that show how factors interrelate—starting with public health topics like COVID-19 and its links to diabetes and obesity—and aggregates thousands of sources, including peer-reviewed research, to illustrate cause-and-effect relationships. The platform is designed for researchers, policymakers, and the public to explore problems, identify intervention points, and make smarter decisions based on how events and conditions influence each other. What sets System apart is its focus on systems thinking and causal inference within a public benefit framework, plus a dedicated platform for visualizing knowledge graphs that connect data to real-world decisions. The company aims to improve collective understanding of complex systems and empower better actions by revealing interdependencies and intervention points across global issues.

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About System

Simplify's Rating
Why System is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & AnalyticsEnterprise SoftwareAI & Machine LearningHealthcare

Company Size

11-50

Company Stage

Grant

Total Funding

$19M

Headquarters

New York City, New York

Founded

2017

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Simplify's Take

What believers are saying

  • System Pro already served nearly 200,000 users since public beta in March 2022.
  • Daily refreshed outputs from 35 million PubMed studies strengthen research utility and retention.
  • Wellcome’s $6.5 million backing funds open-source tools, commons access, and annual conferences.

What critics are saying

  • System Pro stays limited to health and life sciences, delaying broader monetization.
  • Trust hinges on AI summaries; one harmful citation error can destroy researcher confidence.
  • Mission restrictions from Wellcome limit pivots; if subscriptions stall, System becomes a grant-dependent niche.

What makes System unique

  • Adam Bly’s 2018 vision turns scientific literature into causal system maps.
  • System Pro combines PubMed-scale extraction, daily refreshes, and patented graph architecture.
  • Wellcome’s 2025 PRI locked mission, PBC status, and open-access System Graph release.

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Funding

Total Funding

$19M

Above

Industry Average

Funded Over

2 Rounds

Grant funding comparison data is currently unavailable. We're working to provide this information soon!
Grant Funding Comparison Coming Soon

Benefits

Flexible Work Hours

Professional Development Budget

Growth & Insights and Company News

Headcount

6 month growth

↑ 9%

1 year growth

↑ 9%

2 year growth

↓ -4%
PR Newswire
Dec 16th, 2025
Wellcome invests $6.5M in System to organise scientific knowledge as interconnected graph

System, a Public Benefit Corporation building a quantitative model of the world as one interconnected system, has received a $6.5 million program-related investment from Wellcome Trust. This marks one of the foundation's first such investments in public interest technology. The funding will enable System to release the System Graph into the commons, develop open-source tools for researchers, and build a global community of systems thinkers. The System Graph aims to organise data and knowledge across traditional silos like disciplines and scales. Under the agreement, System must maintain its Public Benefit Corporation status for five years and cannot materially change its mission without Wellcome's approval. Founder and CEO Adam Bly said the investment ensures the company's mission remains durable and sustainable whilst driving systems-based research and solutions globally.

Business Wire
May 7th, 2024
Us Medical Innovations Secures Fda Clearance For Canady Helios Cold Plasma(Tm) Ablation System

TAKOMA PARK, Md.--(BUSINESS WIRE)--US Medical Innovations, LLC (USMI) announced today it has received FDA 510k Clearance (K240297) for the Canady Helios Cold Plasma™ (CHCP) Ablation System for the ablation of soft tissue during surgery. The CHCP system consists of the Canady Helios Cold Plasma XL-1000 CP Smart Electrosurgical Generator, Canady Helios Cold Plasma Ablators, Foot Pedal and Trolley Cart. Plasma is the fourth state of matter formed by ionizing neutral gases (i.e. Argon or Helium) combined with electromagnetic fields. The Canady Helios Cold Plasma™ System introduces a novel approach to soft tissue ablation using plasma. The system creates a plasma jet consisting of a pre-programmed, pulsed, non-contact, non-thermal (24 C to 30 C), three-dimensional, Plasma Treated Electromagnetic Field™ (PTEF)

GV Immigration
Apr 27th, 2024
French Language Key to Canada PR Success in Express Entry Draws 2024

Express Entry (EE) System is the top Canada PR pathway for foreign workers.

TipRanks
Apr 12th, 2024
System1 Expands Board with Strategic Director Appointments

System, Inc. has expanded its Board of Directors with the appointments of Charles Ursini and Ryan Caswell as Class II and Class III directors, respectively.

Emovis
Mar 20th, 2024
Emovis Deploys New Roadside System for Major Bridge in Puerto Rico as Part of Continued Partnership with Metropistas

Emovis deploys new roadside System for major Bridge in Puerto Rico as part of continued partnership with Metropistas.

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