T45 Labs

T45 Labs

Develops acquisition-ready cardiovascular medtech startups

Overview

T45 Labs is a Silicon Valley medtech incubator and investment platform that builds acquisition-ready cardiovascular companies. It reduces development risk by guiding technologies through key clinical and regulatory milestones and by refining concepts in validated markets using a best-follower approach. Through T45 Fund-I and T45 Fund-II, it partners with physicians and entrepreneurs to create differentiated cardiovascular startups with clear paths to strategic acquisition and investor returns. The goal is to deliver cardiovascular companies that meet milestones and are attractive exits for strategic buyers and investors.

Significant Headcount Growth

About T45 Labs

Simplify's Rating
Why T45 Labs is rated
C+
Rated C on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Venture Capital

Healthcare

Company Size

11-50

Company Stage

N/A

Total Funding

N/A

Headquarters

Moose, Wyoming

Founded

2022

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Simplify's Take

What believers are saying

  • T45 closed an oversubscribed $25 million Fund I in March 2025.
  • T45 opened Fund II on its website in January 2026, signaling continued capital demand.
  • Advanced NanoTherapies, VahatiCor, and NuevoSono reported 2024 clinical progress toward 2025 milestones.

What critics are saying

  • T45 Fund I supports only three portfolio companies, creating concentration risk.
  • Advanced NanoTherapies, VahatiCor, and NuevoSono still depend on early feasibility studies.
  • A failed FDA path for any lead program destroys T45's value proposition and fundraising story.

What makes T45 Labs unique

  • T45 Labs combines a medical-device incubator, capital provider, and clinical execution engine.
  • Its 25,000-square-foot Silicon Valley facility centralizes engineering, translational work, and clinician collaboration.
  • Dr. Rishi Puri joined as Chief Medical Director in January 2026, deepening cardiovascular credibility.

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Benefits

Remote Work Options

Company Equity

Performance Bonus

Growth & Insights and Company News

Headcount

6 month growth

15%

1 year growth

15%

2 year growth

27%
Yahoo Finance
Mar 19th, 2025
T45 LABS CLOSES OVERSUBSCRIBED $25M T45 FUND I TO ACCELERATE MILESTONE ACHIEVEMENTS FOR PORTFOLIO COMPANIES

T45 Labs, a specialized medical technology innovation company focused on accelerating the development of cardiovascular solutions for large and underserved markets, today announced the successful close of its $25 million T45 Fund I. The oversubscribed fund demonstrates strong investor confidence in T45 Labs' mission to deliver breakthrough cardiovascular technologies that drive meaningful advancements in patient care.

PR Newswire
Mar 19th, 2025
T45 Labs Closes $25M Fund I

T45 Labs announced the successful close of its oversubscribed $25M T45 Fund I to advance cardiovascular medical device development. The fund will support clinical research and milestone achievements for portfolio companies, including Advanced NanoTherapies, Vahaticor, NuevoSono, and ReCava. Located in a 25,000 sq. ft. facility in Silicon Valley, T45 Labs collaborates with clinicians to innovate and commercialize devices.

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