Full-Time

Chief of Staff

Office of the President

Ambience Healthcare

Ambience Healthcare

201-500 employees

Generative AI platform for clinician workflow

Compensation Overview

$185k - $295k/yr

San Francisco, CA, USA

Hybrid

Remote-friendly culture with SF HQ.

Category
Business & Strategy (1)
Required Skills
Financial Modeling
Requirements
  • 5–10+ years of professional experience with a meaningful operating track record
  • People management experience
  • Comfort with financial modeling and quantitative analysis
  • Strong written communication
Responsibilities
  • Quarterback the Office of the President as an operating unit. Youll hold hyper-context across every active workstream partnerships, competitive intelligence, new market analyses, ad hoc deal support, thought leadership and make sure the right people are working on the right problems at the right time. Youll know when to push, when to steer, and when to escalate. Youll set and manage OKRs for the team and drive accountability for follow-through.
  • Building and managing the team. The OOTP is still forming. Youll partner with the recruiting team to help identify and hire the remaining members special projects operators, strategic finance support and then coach, develop, and manage them. This means checking in when someones stuck, helping them break problems down to first principles, and teaching them frameworks so they can solve the next problem independently. You are not a project manager who delegates and checks boxes. Youre a player-coach who can roll up their sleeves and help someone get unstuck when the details get hard.
  • Driving high-stakes partnership initiatives. Ambience is actively building critical external partnerships with ecosystem players including strategic technology partners, health systems, and adjacent platforms. Youll help craft compelling joint value narratives, coordinate across internal and external stakeholders, and support the analytical work (financial modeling, market sizing, deal structuring) that underpins these relationships. When a 72-hour contract negotiation sprint happens, youre in the room.
  • Supporting internal AI-first initiatives. Youll help build and scale Ambience's company-wide AI shared knowledge management system making sure that institutional knowledge is captured, searchable, and continuously improving. This includes helping the OOTP itself operate as an exemplar AI-first team: using AI to do research, generate first drafts, prep for meetings, track decisions, and scale what one person can accomplish.
  • Serving as Mike's right hand. Youll collect insights from across the company, see around corners, and bring Mike information he wouldnt otherwise have. Youll draft and refine memos, prep materials for board meetings and keynotes, and manage the flow of decisions so Mike's time and energy are spent on the highest-leverage problems. Youll partner closely with Mike's Executive Assistant to ensure his calendar reflects actual priorities.
Desired Qualifications
  • Strongly preferred domain expertise in one or more of the following: Foundation models / hyperscalers; Health systems; Adjacent healthcare markets such as revenue cycle management, payers, or life sciences
  • Mutual fit matters deeply here. This is a true partnership you\'ll spend more time working together than with almost anyone else at the company. As you and Mike get to know each other through the interview process, we hope you\'ll build conviction on fit, trust, and whether this is a partnership where both sides learn from and elevate each other. That signal matters as much to us as any credential on your resume.
  • High internal locus of control. You believe that outcomes are within your influence. You take extreme ownership when something goes wrong, you ask what you could have done differently before looking outward.
  • You think about AI in terms of compounding systems, not just efficiency gains. Using AI to draft an email faster is table stakes. We care about whether you build systems that get smarter over time where each use makes the next one better. We'll ask you how you've used AI in the last six months, and we want to see what you've built.
  • Slope over y-intercept. We value your growth rate more than your starting point. Every six months, you should be able to look back and point to something meaningful you couldn't have done six months prior.

Ambience Healthcare provides AI-powered tools to support clinicians and streamline healthcare workflows. It develops an AI operating system and product suite that integrates generative AI into clinical documentation and administrative tasks, working with hospitals and clinics across North America through a subscription model. The software plugs into electronic health records (EHRs) to structure data for better reporting, research, and daily workflows. Unlike competitors that may offer standalone apps, Ambience Healthcare partners with large health systems to embed AI directly into clinical processes, focusing on reducing clinician burnout and boosting system efficiency while maintaining high-quality care. The company’s goal is to make healthcare workflows smoother and more efficient by embedding AI into everyday clinical operations.”} വ```

Company Size

201-500

Company Stage

Series C

Total Funding

$343M

Headquarters

San Francisco, California

Founded

2020

Simplify Jobs

Simplify's Take

What believers are saying

  • Houston Methodist achieved 40% documentation reduction, 27% more patient face time post-rollout.
  • MultiCare 92% adoption after 2025 evaluation, expanding to 1,500 clinicians in three months.
  • $190M funding filed supports platform expansion into revenue integrity and care orchestration.

What critics are saying

  • Epic's native Hyperdrive AI erodes Ambience's integration by Q2 2027 per April 2026 call.
  • Nuance DAX Copilot wins Mayo Clinic contracts, undercutting pricing by Q1 2027.
  • HHS OIG audits upcoding in AI docs, fining MultiCare $15M+ by mid-2027.

What makes Ambience Healthcare unique

  • Conditions Advisor launched November 3, 2025, surfaces missed diagnoses from longitudinal records.
  • Chart Chat for Nursing integrates EHR for nurses, live at Cleveland Clinic April 2026.
  • Supports 200+ subspecialties across ambulatory, emergency, inpatient with 80%+ utilization.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Unlimited Paid Time Off

401(k) Retirement Plan

Company Equity

Professional Development Budget

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

3%

2 year growth

9%
Business Wire
Apr 1st, 2026
Ambience Healthcare launches Chart Chat for Nursing, first EHR-integrated conversational AI tool for inpatient nurses

Ambience Healthcare has launched Chart Chat for Nursing, the first EHR-integrated conversational AI tool for inpatient nursing. The platform allows nurses to ask plain-language questions about patient charts, synthesising information from physician notes, hospital policies, orders and lab results in seconds, with full source citations. Cleveland Clinic is piloting the technology, which addresses a critical challenge: studies show documentation consumes 25% to 41% of nurses' time in complex settings. The tool lives inside the EHR and helps nurses quickly understand patient histories before documentation begins. Chart Chat for Nursing features a three-tier safety architecture, including real-time response monitoring and continuous nurse feedback. It's limited to clinical questions and explicitly flags ambiguity or insufficient data rather than generating uncertain answers.

The Associated Press
Feb 17th, 2026
Houston Methodist deploys Ambience Healthcare's AI platform enterprise-wide, achieving 40% reduction in documentation time

Ambience Healthcare has deployed its AI platform for clinical documentation across Houston Methodist's ambulatory, emergency and inpatient settings. The healthcare system selected Ambience after evaluating multiple ambient AI technologies and measuring strong adoption rates and efficiency improvements. Following the enterprise-wide rollout, Houston Methodist observed a 27% increase in patient face time, 40% reduction in documentation time, and 33% decrease in after-hours work. The platform is used in 80% of patient visits across different specialties, with clinicians completing 1.3 additional voluntary visits per day. The AI platform provides real-time, coding-aware documentation within electronic health records, supporting over 200 specialties. Ambience Healthcare, founded in 2020 and headquartered in San Francisco, is backed by Oak HC/FT, Andreessen Horowitz, OpenAI Startup Fund and Kleiner Perkins.

Business Wire
Feb 17th, 2026
Ambience Healthcare Announces Houston Methodist Enterprise Rollout of AI Platform to Enhance Patient Care and Clinical Workflows

Ambience Healthcare announces Houston Methodist enterprise rollout of AI platform to enhance patient care and clinical workflows. Houston Methodist sees 40% reduction in documentation time and 80% utilization across specialties. SAN FRANCISCO & HOUSTON-(BUSINESS WIRE)-Ambience Healthcare announced today that its AI platform for clinical documentation and revenue integrity has been successfully deployed across Houston Methodist. The nationally recognized leader in clinical excellence, innovation, and technology-enabled care is rolling out the platform enterprise-wide across its ambulatory, emergency and inpatient settings to support clinicians and nurses with documentation and clinical workflows. Following a broad evaluation of multiple leading ambient AI technologies, Houston Methodist selected Ambience after measuring strong clinician adoption and measurable improvements in efficiency, experience and care delivery. "Our goal was to adopt an ambient AI solution that could scale across primary, specialty and subspecialty care, covering ambulatory, emergency, and inpatient settings," said Dr. Jordan Dale, chief medical information officer and chief health AI officer at Houston Methodist. "Ambience took on the challenge of our complex specialty needs and extended its platform to our emergency and hospital medicine teams. As a result, our clinicians can complete documentation with system-wide context more efficiently while dedicating more attention to our patients." This milestone builds on an initial phased ambulatory deployment in which Houston Methodist expanded the use of ambient AI to emergency and inpatient settings. As the platform was deployed at scale, the team observed measurable changes in how clinicians documented care, managed workflows, and engaged with patients, including: Patient experience and care delivery * 27% increase in patient face time Clinician adoption and engagement * 80% of patient visits utilize Ambience across different specialties Clinician productivity and efficiency * 40% reduction in documentation time * 33% reduction in after-hours "pajama time" * 13% decrease in time to close encounters * +1.3 voluntary visits per clinician per day In addition to improving the clinician experience, Ambience is designed to support health systems' operational and financial objectives through compliant, coding-aware documentation. These capabilities are intended to help protect revenue integrity, reduce downstream CDI queries, limit billing risk and support a clear return on investment. "With sustained utilization across our clinicians, adopting ambient AI technology has been highly impactful, allowing the chart to work for the physician rather than the physician working for the chart," said Roberta Schwartz, executive vice president and chief innovation officer at Houston Methodist. "Seeing the joy our physicians express when they can focus fully on their patients has been remarkable." This enterprise rollout represents a key milestone in Houston Methodist's long-term digital and clinical transformation strategy, with Ambience positioned as a strategic platform across outpatient, inpatient and specialty care settings. "Houston Methodist is widely recognized for its leadership in clinical innovation and its disciplined approach to technology adoption," said Nikhil Buduma, Co-Founder and CEO at Ambience Healthcare. "We're proud to support their efforts to operationalize ambient AI at enterprise scale, including in emergency and inpatient settings where the complexity is highest." About Houston Methodist Houston Methodist is one of the nation's leading health systems and academic medical centers. The health system consists of nine hospitals: Houston Methodist Hospital, its flagship academic hospital in the Texas Medical Center, seven community hospitals and one long-term acute care hospital throughout the Greater Houston metropolitan area. Houston Methodist also includes a research institute; a comprehensive residency program; international patient services; freestanding comprehensive care, emergency care and imaging centers; and outpatient facilities. Houston Methodist employs approximately 35,000 people. In 2025, Houston Methodist had more than 2.4 million outpatient visits and more than 151,000 admissions. About Ambience Healthcare Ambience Healthcare is the leading AI platform for clinical documentation and revenue integrity. Trusted by top health systems across North America, Ambience's platform is live across outpatient, emergency and inpatient settings, supporting more than 200 specialties with real-time, coding-aware documentation directly within major EHRs. Founded in 2020 by Mike Ng and Nikhil Buduma, Ambience is headquartered in San Francisco and backed by Oak HC/FT, Andreessen Horowitz (a16z), OpenAI Startup Fund, Kleiner Perkins, and other leading investors. Contacts. Media Contact Ana Dorta Aria Marketing for Ambience Healthcare [email protected] 914.393.6667 More News From Ambience Healthcare SAN FRANCISCO-( BUSINESS WIRE )-Ambience Healthcare, the leading AI platform for clinical documentation and revenue integrity, today announced expanded "chart awareness" across its capabilities. Chart awareness enables AI to interpret a patient's full longitudinal record, including prior notes, diagnoses, labs, imaging, medications, pathology, and problem lists. That understanding is applied directly across documentation and coding workflows. While AI scribes focus on capturing clinical convers... SAN FRANCISCO-( BUSINESS WIRE )-Ambience Healthcare, the leading AI platform transforming clinical documentation and revenue integrity, today announced the appointment of Mike Valli as Chief Revenue Officer (CRO) and Chief Value Officer (CVO). In this dual role, Valli will lead Ambience's global go-to-market initiatives while also owning the company's enterprise value framework - ensuring customers realize measurable, durable clinical and financial outcomes from Ambience's AI platform. This appoi... SAN FRANCISCO-( BUSINESS WIRE )-Following one of the most comprehensive evaluations of ambient AI technology in healthcare, MultiCare Health System, based in Tacoma, WA, has selected Ambience Healthcare for an enterprise-wide deployment of its AI platform for documentation, coding, and clinical workflows. The initiative advances clinician well-being, patient experience, and documentation quality across the organization. The deployment follows a rigorous, head-to-head evaluation throughout 2025...

Business Wire
Feb 12th, 2026
Ambience Healthcare expands AI platform with chart-aware clinical documentation across 200+ specialties

Ambience Healthcare has expanded "chart awareness" across its AI platform, enabling the system to interpret patients' full longitudinal records including prior notes, diagnoses, labs, imaging and medications. The technology applies this understanding across documentation and coding workflows. The expanded capabilities include chart-aware patient summaries, assessment and plan generation, automated diagnostics extraction, and coding assistance grounded in longitudinal chart reasoning. These features aim to improve documentation accuracy, reduce compliance risk and strengthen revenue integrity. Ambience now supports over 200 subspecialties across outpatient, emergency and inpatient settings, achieving over 90% clinician adoption at enterprise deployments. Health systems have reported up to 40% reductions in documentation time and more than $13,000 in incremental annual revenue per clinician through improved coding accuracy. The San Francisco-based company is backed by Oak HC/FT, Andreessen Horowitz, OpenAI Startup Fund and Kleiner Perkins.

Business Wire
Feb 9th, 2026
Ambience Healthcare appoints Mike Valli as chief revenue officer and chief value officer

Ambience Healthcare has appointed Mike Valli as Chief Revenue Officer and Chief Value Officer. In this dual role, Valli will lead global go-to-market initiatives whilst ensuring customers achieve measurable clinical and financial outcomes from Ambience's AI platform for clinical documentation and revenue integrity. Valli brings over 15 years of healthcare technology experience, most recently serving as Chief Commercial Officer at symplr. He previously spent a decade at Optum in senior executive roles including Market President, building major hospital partnerships. The appointment comes as Ambience expands across large health systems and academic medical centres. The company also named Richa Gupta as Vice President of Care Transformation and Jeffrey Gerson as Vice President of Marketing. Founded in 2020, Ambience is backed by Oak HC/FT, Andreessen Horowitz, OpenAI Startup Fund and Kleiner Perkins.