Full-Time

Scientist – NGS Core Lead

Posted on 11/7/2024

Flagship Pioneering

Flagship Pioneering

201-500 employees

Biotechnology firm creating health and sustainability solutions

Biotechnology
Healthcare

Entry

Cambridge, MA, USA

Category
Computational Biology
Genomics
Biology Lab & Research
Biology & Biotech
Requirements
  • PhD in biology or a related discipline with 0-2 years of experience working in biotech or a related industry, or M.S. with 6+ years of relevant experience.
  • Expertise with a variety of Illumina-based NGS methods, including experience with RNA-centric methods and experience developing or implementing custom NGS methods.
  • Demonstrated ability to drive improvements in quality, reproducibility, and/or scale of NGS methods.
  • Experience interpreting NGS data in support of quality assessment, methodology improvement, and experimental troubleshooting.
  • Experience managing or coordinating work of a small team.
  • Demonstrated ability to implement and support technical and operational processes that contribute to the successful execution of scientific research at scale.
  • Excellent communication skills and the ability to clearly explain NGS methods and considerations around their application to team members of diverse backgrounds.
  • Detail-oriented and organized with a strong ability to manage multiple experiments in parallel.
Responsibilities
  • Support company-wide use of tRNA sequencing by coordinating and overseeing work of the NGS core.
  • Contribute to tRNA sequencing work by performing RNA extraction, library preparation, and data review.
  • Drive the continued improvement of tRNA sequencing by identifying and implementing solutions to problems of scale, reproducibility and quality of the method.
  • Coordinate with stakeholders relating to sequencing requests, supporting experimental design, sample submission, tracking experiment status, and troubleshooting unexpected results as needed.
  • Support the transition of sequencing methods from the late stages of their development to establish them as pipeline methods.

Flagship Pioneering fosters a culture of groundbreaking advancements in biotechnology, emphasizing an ecosystem approach that synergizes human health and sustainability. Their business model not only focuses on creating transformative products but also incubates leading companies like Moderna and Indigo Agriculture, positioning them at the forefront of scientific innovation and industry leadership. This approach offers employees a unique opportunity to be part of a pioneering team that drives real-world impacts across multiple sectors.

Company Stage

N/A

Total Funding

$10.2B

Headquarters

Cambridge, Massachusetts

Founded

2000

Simplify Jobs

Simplify's Take

What believers are saying

  • Strategic partnership with Pfizer enhances drug discovery for cardiometabolic and cancer treatments.
  • AI-driven platforms like Montai's CONECTA™ accelerate identification of therapeutic targets.
  • Focus on variant-resilient vaccines positions Apriori Bio for future pandemic challenges.

What critics are saying

  • Over-reliance on partnerships like Pfizer could pose risks if expectations aren't met.
  • Rapid expansion may strain resources and management if not well-integrated.
  • High-profile executive appointments may lead to cultural integration challenges.

What makes Flagship Pioneering unique

  • Flagship Pioneering creates first-in-category ventures transforming health and sustainability.
  • The company uses an evolutionary methodology to achieve transformational outcomes.
  • Flagship combines innovation, leadership, and capital management in a single enterprise.

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