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Orca Bio

Develops and commercializes safer cell therapies

Warehouse Manager

Full-TimePosted on 10/15/2026
$100k - $145k/yr+ Pre-IPO equity + Annual bonus
Senior
Bachelor's
Sacramento, CA, USA
In Person
Warehouse & Fulfillment

About the job

Requirements
  • At least 5 years of experience in warehouse operations, including at least 2 years in a supervisory or management role.
  • Strong knowledge of warehouse management software and experience with inventory management or enterprise resource planning software.
  • Proven ability to manage and motivate a team effectively.
  • Knowledge of safety regulations and compliance requirements in a warehouse environment.
Responsibilities
  • Oversee daily warehouse operations, including material receipt, inspection, labeling, storage, put-away, and distribution, ensuring compliance with applicable Good Manufacturing Practice, Good Tissue Practice, and Good Distribution Practice requirements, site procedures, and safety standards.
  • Maintain accurate inventory records, material status, storage locations, and traceability within inventory management systems; oversee cycle counts, inventory reconciliations, discrepancy investigations, and corrective actions to support inventory accuracy and material availability.
  • Ensure incoming raw materials, reagents, consumables, and packaging components are received, documented, identified, stored, and controlled according to their requirements and quality status before use.
  • Coordinate material picking, kitting, and staging to support manufacturing schedules and patient-specific production needs; ensure kits are accurate, complete, appropriately controlled, and delivered to production in the required quantities and timeframes.
  • Oversee timely transport of materials to production suite material airlocks and replenishment of materials in cleanrooms, gowning areas, laboratories, packaging areas, and training spaces, maintaining appropriate stock levels and material controls.
  • Establish and maintain stocking strategies, point-of-use inventory, and Kanban replenishment systems for frequently used consumables; monitor usage and replenishment needs to prevent stockouts, minimize excess inventory, and support efficient material flow.
  • Lead, develop, and prioritize material handlers' work, ensuring adequate coverage, clear assignments, adherence to procedures, and completion of required Good Manufacturing Practice, safety, and job-specific training.
  • Partner with Production Planning, Material Planning, Procurement, Manufacturing, Quality, and Facilities to align material availability, receiving priorities, inventory replenishment, and delivery schedules with manufacturing demand and site operations.
  • Develop and monitor warehouse performance metrics, including inventory accuracy, material availability, kitting readiness, replenishment timeliness, and stockouts; drive process standardization, deviation reduction, workflow efficiency, and scalable warehouse practices to support commercial growth.
  • Oversee the department's daily workflow, ensure standard work is consistently performed and activities comply with safety and company policies, recruit, interview, hire, and train new staff, provide constructive and timely feedback through regular performance evaluations, and perform other assigned duties.
Desired Qualifications
  • Certification in Production and Inventory Management or Logistics, Transportation and Distribution is a plus.
  • Familiarity with Good Manufacturing Practices, document management systems, and electronic batch records is preferred.
  • A bachelor's degree in Supply Chain Management, Logistics, Business Administration, or a related field, or equivalent experience, is preferred.

About the company

Orca Bio develops and commercializes cell therapies to improve outcomes for patients. It works by researching, developing, and producing therapies that use the body’s own cells to treat diseases, with products sold to healthcare providers who administer them to patients. The company aims to enhance the safety and effectiveness of cell therapies, making treatments more reliable for conditions that lack good options. Orca Bio differentiates itself through its focus on delivering safer, more effective therapies and by fostering a strong team culture with active stakeholder communication, including a regularly updated newsroom. Overall, its goal is to expand access to improved cell therapies and become a leading player in the cell therapy market.

Company Size

201-500

Company Stage

Debt Financing

Total Funding

$542M

Headquarters

North Fair Oaks, California

Founded

2016

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Simplify's Take

What believers are saying

  • FDA approval on June 30, 2026 validates Orca Bio's platform and pipeline.
  • The company raised $250 million in December 2025, funding launch and expansion.
  • Princeton capacity and Sacramento hiring support commercialization and faster nationwide patient delivery.

What critics are saying

  • TREGZI costs $428,000, forcing transplant centers and payers into tough coverage fights.
  • Complex donor-specific manufacturing can bottleneck supply, delaying launches beyond the planned 25 centers.
  • Any post-marketing safety signal or FDA CMC issue would cripple Orca Bio's only commercial product.

What makes Orca Bio unique

  • Orca Bio's TREGZI won FDA approval on June 30, 2026, first precision cell therapy.
  • Its donor-derived regulatory T-cell design directly reduces chronic GVHD after transplant.
  • Princeton and Sacramento manufacturing create a bicoastal vein-to-vein network for personalized production.

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Benefits

  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • Life Insurance
  • Unlimited Paid Time Off
  • 401(k) Retirement Plan
  • Parental Leave

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

3%

2 year growth

0%
Associated Press
Jul 1st, 2026
FDA approves Tregzi, first donor immune cell therapy cutting serious transplant complications in blood cancer patients by 70%

The US Food and Drug Administration has approved Tregzi, the first regulatory T cell-based immunotherapy for improving chronic graft-versus-host disease-free survival in adult blood cancer patients undergoing stem cell transplantation. The treatment uses donor-derived immune cells to help fight cancer whilst reducing the risk of chronic GVHD, a serious complication where transplanted donor cells attack the patient's body. In the PRECISION-T trial involving 187 patients, 78% of those receiving Tregzi achieved chronic GVHD-free survival at one year, compared to 38.4% receiving standard transplants. Only 12.6% of Tregzi patients developed serious chronic GVHD within one year versus 44% in the control group. The treatment, developed by Orca Biosystems, received Orphan Drug and Regenerative Medicine Advanced Therapy designations.

Fierce Pharma
Jul 1st, 2026
Orca Bio secures FDA approval for $428K cell therapy Tregzi, eyes potential IPO

Orca Bio has secured FDA approval for Tregzi, a first-of-its-kind engineered cell therapy for blood cancer patients requiring transplants. The allogeneic regulatory T cell-based immunotherapy is approved as an alternative stem cell transplant to improve survival free of chronic graft-versus-host disease in adults with hematological malignancies. In the phase 3 Precision-T trial involving 187 patients, 78% who received Tregzi were alive and free from chronic GVHD at one year, compared to 38% with standard transplants—a 74% improvement. Overall survival was 94% versus 83%. Orca is pricing Tregzi at $428,000 wholesale acquisition cost. The company recently raised $250 million and is launching at select centres, aiming for 25 by year-end. CEO Nate Fernhoff said the company is "well capitalised" for launch but didn't rule out a future IPO.

Associated Press
Jun 30th, 2026
Orca Bio's TREGZI becomes first FDA-approved precision cell therapy for blood cancer transplants

Orca Bio has received US FDA approval for TREGZI, the first precision-engineered cell therapy for matched-donor hematopoietic stem cell transplantation in adults with hematological malignancies. The therapy uses donor cells to reconstitute the immune system whilst suppressing graft-versus-host disease (GVHD). The approval is based on the Phase 3 Precision-T study of 187 patients with acute myeloid leukaemia, acute lymphoblastic leukaemia, myelodysplastic syndrome and mixed-phenotype acute leukaemia. Results showed 78% chronic GVHD-free survival at 12 months with TREGZI compared to 38% with conventional transplant. Overall survival was 94% versus 83%, whilst non-relapse mortality was 3% compared to 13%. TREGZI is a personalised treatment manufactured for each patient using living cells from a matched donor.

San Francisco Biotechnology Network
Jun 15th, 2026
Orca Bio expands Sacramento workforce, adds East Coast manufacturing site ahead of approval.

Orca Bio expands Sacramento workforce, adds East Coast manufacturing site ahead of approval. June 15, 2026 san francisco biotechnology network news news, syndication comments off on orca Bio expands Sacramento workforce, adds East Coast manufacturing site ahead of approval. Orca Bio, a biotechnology company that works in precision cell therapy, has expanded its Sacramento workforce and added an East Coast manufacturing center in Princeton, New Jersey, as it prepares for commercialization. Click here to view original post

Business Wire
Jun 15th, 2026
Orca Bio expands manufacturing for Orca-T launch with East Coast facility and tripled workforce

Orca Bio has expanded its manufacturing capabilities ahead of the potential launch of its lead cell therapy, Orca-T, adding East Coast manufacturing capacity in Princeton, New Jersey, and tripling its West Coast manufacturing workforce in Sacramento, California. The Princeton facility will serve as a strategic East Coast manufacturing bridge, initially producing therapies for ongoing clinical programmes and supporting commercial production following potential FDA approval. The bicoastal network aims to reduce "vein-to-vein" time for patients nationwide. Orca Bio has more than tripled its Sacramento operations team over the past year, enhancing expertise in manufacturing, supply chain logistics and quality assurance. Orca-T's Biologics License Application is under FDA review, with a target action date of 6 July 2026.