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Amgen

Makes biotech medicines for serious illnesses

Senior Manager, Manufacturing Systems Engineering (ASRS)

Engineering LeadershipConfirmed live in the last 24 hours
Full-timeNew Albany, OH, USAIn-person

About the Job

Requirements

  • Doctorate degree and 2 years of engineering, automation, manufacturing systems, logistics, or related experience; or master's degree and 6 years of relevant experience; or bachelor's degree and 8 years of relevant experience; or associate's degree and 10 years of relevant experience; or high school diploma/GED and 12 years of relevant experience.
  • Experience leading engineers, technicians, or multidisciplinary technical teams in an operating manufacturing or distribution environment is preferred.
  • Experience with ASRS, AGVs, AutoStore, conveyors, warehouse control systems, SAP EWM, or other automated material handling systems is preferred.
  • Experience establishing technical support and escalation practices for continuous operations is preferred.
  • Demonstrated ability to lead complex troubleshooting, root cause analysis, and sustained reliability improvements is preferred.
  • Experience with commissioning, qualification, change control, and investigations in a regulated manufacturing environment is preferred.
  • Demonstrated experience managing the lifecycle of complex automated systems, including continuous improvement, system upgrades, obsolescence management, expansion projects, and integration of new functionality is preferred.
  • Experience providing engineering oversight for system modifications or expansion projects while maintaining design integrity, technical standards, and system reliability is preferred.
  • Ability to define ownership and coordinate work across Operations, Engineering, Maintenance, Digital Technology, Quality, EHSS, Global Engineering/ETA, and external vendors is preferred.
  • Strong skills in prioritization, decision-making, communication, and developing technical talent are preferred.
  • Ability to balance urgent production needs with safe, compliant, reliable, and sustainable long-term solutions is preferred.

Responsibilities

  • Lead, coach, and develop a team of engineers, system owners, and technicians; set accountabilities, technical priorities, training plans, and performance expectations.
  • Establish support coverage, escalation paths, and recovery procedures for automated warehouse systems in a 24/7 operation.
  • Direct technical response to equipment failures, interface errors, and material flow interruptions, coordinating troubleshooting and restoration with Warehouse Operations, Manufacturing, Maintenance, Digital Technology, Quality, and equipment vendors.
  • Review system availability, transaction performance, recurring faults, and recovery times, and use performance data to prioritize corrective actions and reliability improvements.
  • Ensure system owners maintain current procedures, technical documentation, spare parts strategies, preventive maintenance requirements, and vendor support plans.
  • Partner with Warehouse Operations to ensure automated systems support inbound, outbound, and manufacturing material flows and resolve technical constraints affecting those flows.
  • Provide engineering oversight for the end-to-end automated warehouse system, including ASRS equipment, conveyors, AGVs, AutoStore, warehouse control software, host interfaces, and connections to manufacturing and packaging lines.
  • Define and maintain technical ownership across the team, including equipment, controls, software interfaces, and system performance.
  • Lead or support investigations, root cause analysis, corrective actions, and change controls involving automated warehouse systems.
  • Ensure changes to equipment, controls, software, and interfaces are assessed, documented, tested, and implemented in accordance with site quality and safety requirements.
  • Partner with Global ETA/ASRS technical leadership to maintain system integrity, reliability, resilience, and alignment with enterprise engineering standards and strategies, including lifecycle changes, technology upgrades, major modifications, and new functionality.
  • Partner with EHSS on equipment safety, access controls, risk assessments, and safe maintenance and recovery practices.
  • Coordinate with Facilities Engineering on warehouse building systems and storage environments where performance affects automated operations.
  • Lead engineering support for the design, integration, commissioning, qualification, and operational readiness of new or modified automated warehouse capabilities.
  • Ensure integration among ASRS, AGVs, AutoStore, warehouse control systems, SAP EWM, and manufacturing/packaging lines, with clear testing and handoff to operations.
  • Lead automated warehouse continuous improvement and engineering projects, including system optimization, capacity improvements, functionality enhancements, complex system integration, and business-driven expansion projects.
  • Provide engineering oversight for automated warehouse expansion and modification projects to ensure engineering design quality, system integrity, and continued compliance with technical requirements and standards.
  • Develop team capability, procedures, and support arrangements before new systems enter routine operation.
  • Own the technical improvement and lifecycle roadmap for automated warehouse systems, balancing immediate operational needs with long-term reliability, resilience, capacity, performance, and obsolescence risks.
  • Support capital planning, equipment upgrades, technology refresh, vendor strategy, and expansion projects.
  • Build effective working relationships with equipment manufacturers, system integrators, Global ETA, and internal partners.

About the Company

Amgen

Makes biotech medicines for serious illnesses

Amgen develops and makes biologic medicines, which are drugs built from proteins and antibodies grown in living cells, for serious conditions such as heart disease, cancer, and bone loss. Its anemia drug Epogen, approved in 1989, became one of the biotechnology industry's first blockbuster medicines. Amgen grows these drugs in large tanks called bioreactors, and its products include the cholesterol drug Repatha, the bone-building drug Evenity, and the severe asthma drug Tezspire. It earns money by selling these medicines, mostly through large drug wholesalers that supply hospitals and pharmacies. Amgen was founded in 1980 and is based in Thousand Oaks, California.

Company size
10,001+
Company stage
IPO
Headquarters
Thousand Oaks, CA
Founded
1980

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