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Genesis Molecular AI

AI-driven drug discovery platform for pharma

Infrastructure Engineer - Core Infrastructure

Full-Time
No salary listed
Senior
San Mateo, CA, USA
In PersonOn-site role in San Mateo, California.
DevOps & InfrastructurePlatform Engineering

About the job

Requirements
  • 5+ years of experience building and maintaining cloud infrastructure at scale, e.g. within AWS or GCP
  • Proficient with Python, Bash, Terraform, Ray and Kubernetes
Responsibilities
  • Work on our infrastructure team to maintain and grow our multi-cloud compute infrastructure that supports our ML model training, computational chemistry research, and ongoing drug discovery efforts
  • Build out our configuration and procedures for monitoring, resource allocation, and deployment automation, as we continue to grow our autoscaling compute clusters to handle larger workloads
  • Work on orchestration scheduling framework to increase our execution throughput, reliability, and compute utilization across heterogeneous pipelines
Desired Qualifications
  • Ideally, experience building and maintaining compute clusters running distributed ML training jobs with 1,000+ GPUs
  • Nice to have: hands-on experience with physical hardware + datacenter management

About the company

Genesis Molecular AI uses artificial intelligence to speed up drug discovery for the pharmaceutical industry. It combines 3D spatial graph modeling and advanced molecular simulation to generate and evaluate potential drug candidates and to uncover novel protein targets. The platform translates complex molecular data into actionable candidates by representing molecules in 3D graphs and running simulations to predict how they bind to target proteins, helping partners identify promising therapies. The company differentiates itself by integrating 3D spatial graph modeling with detailed molecular simulations to explore untapped chemical space and novel targets, and by focusing on business-to-business partnerships with pharma and biotech companies. Its goal is to accelerate drug discovery for partners by delivering AI-generated candidates and enabling faster progression from target to therapy.

Company Size

51-200

Company Stage

Late Stage VC

Total Funding

$400.1M

Headquarters

San Mateo, California

Founded

2019

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Simplify's Take

What believers are saying

  • May 2026 Incyte expansion delivered $120 million upfront, including $40 million equity.
  • Incyte will share proprietary data and fund compute, improving Genesis model training.
  • Genesis claims Pearl outperformed all cofolding models on OpenBind in October 2025.

What critics are saying

  • Incyte owns exclusive commercialization rights, limiting Genesis’s downstream capture through 2026.
  • OpenAI, Recursion, and Schrödinger intensify AI-drug-discovery competition for talent and partners.
  • If Pearl and GEMS miss wet-lab success, Genesis becomes a services vendor.

What makes Genesis Molecular AI unique

  • GEMS combines foundation models, physical simulation, and proprietary experimental data.
  • Genesis secured Incyte’s exclusive 2025 and expanded 2026 collaboration rights.
  • Sergey Edunov joined in December 2025 to scale foundation-model leadership.

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Benefits

  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • 401(k) Retirement Plan
  • Unlimited Paid Time Off
  • Parental Leave
  • Disability Insurance
  • Life Insurance

Growth & Insights and Company News

Headcount

6 month growth

3%

1 year growth

6%

2 year growth

7%
Business Wire
May 21st, 2026
Incyte and Genesis Expand Molecular AI Collaboration to Accelerate Drug Discovery

Incyte and Genesis expand molecular AI collaboration to accelerate 
drug discovery

Business News Today
Dec 3rd, 2025
Can Genesis Molecular AI leap ahead in biotech with Meta's Llama leader now onboard?

Can Genesis Molecular AI leap ahead in biotech with Meta's Llama leader now onboard? Genesis Molecular AI hires Meta's Llama leader Sergey Edunov to lead foundation models. Discover how this move strengthens its AI drug discovery platform. Genesis Molecular AI, the foundation model-driven drug design firm formerly known as Genesis Therapeutics, has appointed Sergey Edunov as Senior Vice President of Foundation Models. The executive hire marks a strategic inflection point as the company prepares to scale its GEMS platform and unveil new generative model research at the NeurIPS 2025 conference. Sergey Edunov is best known for his leadership role in developing Meta Platforms' Llama 2 and Llama 3 large language models. He brings over two decades of software engineering and AI research experience, having previously served as Senior Director of AI Research in Meta's generative AI division. His arrival at Genesis Molecular AI signals the firm's ambition to compete at the highest levels of foundation model development applied to molecular design.

Latest Nigerian News
Aug 7th, 2025
Genesis Therapeutics raises $52M for AI drug discovery

Genesis Therapeutics has successfully raised a $52 million A round to advance its AI-focused drug discovery mission. The company employs a novel simulation approach and a cross-disciplinary team to efficiently explore the vast array of potential medicinal molecules.

Today Media
May 28th, 2025
Incyte aims to accelerate drug research with AI collaboration

Earlier this year, Incyte inked a deal with Genesis Therapeutics to use the biotech company's AI platform to develop small molecule medicines.

Fierce Biotech
Feb 20th, 2025
Incyte pens $885M biobucks AI pact to use Genesis' GEMS to develop new drugs

Incyte is sticking to its strategy this year of finding "early-stage, exotic stuff" - paying Genesis Therapeutics $30 million upfront to use the biotech's artificial intelligence platform to develop small molecule medicines against undisclosed targets.