Full-Time

Product Manager

Updated on 8/19/2026

System

System

11-50 employees

Causal, data-driven maps of complex systems

No salary listed

New York, NY, USA

Hybrid

Remote work is available, but the posting does not state whether it is fully remote or hybrid.

Category
Product (1)
Required Skills
Agile
Product Management
Product Design
Data Analysis

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Requirements
  • At least 3 years of experience in product management, product design, or a related discipline.
  • A track record of shipping products in agile, fast-moving environments.
  • Experience working in or adjacent to data-heavy or technically complex products.
  • Ability to balance user empathy with systems-level thinking.
  • Comfort with ambiguity and a bias toward clarity.
Responsibilities
  • Define and drive the product vision in close partnership with engineering, data, and research teams.
  • Translate complex systems problems into elegant, human-centered experiences.
  • Conduct user research to understand the needs, mental models, and workflows of systems thinkers.
  • Own the product roadmap and prioritize with clarity, purpose, and data.
  • Collaborate across functions to ship meaningful, high-quality product experiences.
  • Contribute to a culture of curiosity, craft, and continuous improvement.
Desired Qualifications
  • Experience designing or managing products in healthcare, life sciences, or enterprise data platforms.
  • Experience conducting qualitative research with technical or clinical users.
  • Background in or exposure to systems thinking frameworks.

System, Inc. helps people understand and address complex global problems by turning vast data into system maps. It builds data-driven graphical models that show how factors interrelate—starting with public health topics like COVID-19 and its links to diabetes and obesity—and aggregates thousands of sources, including peer-reviewed research, to illustrate cause-and-effect relationships. The platform is designed for researchers, policymakers, and the public to explore problems, identify intervention points, and make smarter decisions based on how events and conditions influence each other. What sets System apart is its focus on systems thinking and causal inference within a public benefit framework, plus a dedicated platform for visualizing knowledge graphs that connect data to real-world decisions. The company aims to improve collective understanding of complex systems and empower better actions by revealing interdependencies and intervention points across global issues.

Company Size

11-50

Company Stage

Grant

Total Funding

$19M

Headquarters

New York City, New York

Founded

2017

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Simplify Jobs

Simplify's Take

What believers are saying

  • Wellcome added $6.5 million on December 16, 2025, validating public-interest demand.
  • System Health launched the Clinical Graph and EHR integrations in 2026.
  • System's July 22, 2026 benchmark claims category-leading diagnostic performance on MIMIC-IV-Ext-DiReCT.

What critics are saying

  • Elicit, Consensus, and Perplexity already dominate evidence search; System Pro faces commoditization.
  • Wellcome's 2025 PRI restricts charter changes for five years, limiting strategic pivots.
  • Google Data Commons GA on August 4, 2026 compresses System's graph-infrastructure moat.

What makes System unique

  • System’s patented graph architecture unifies health, climate, and economics into one model.
  • System Pro targets health and life-sciences researchers with explainable, cited synthesis.
  • Wellcome-backed commons release in 2026 differentiates System as public-interest infrastructure.

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Benefits

Flexible Work Hours

Professional Development Budget

Growth & Insights and Company News

Headcount

6 month growth

4%

1 year growth

-4%

2 year growth

-4%
PR Newswire
Dec 16th, 2025
Wellcome invests $6.5M in System to organise scientific knowledge as interconnected graph

System, a Public Benefit Corporation building a quantitative model of the world as one interconnected system, has received a $6.5 million program-related investment from Wellcome Trust. This marks one of the foundation's first such investments in public interest technology. The funding will enable System to release the System Graph into the commons, develop open-source tools for researchers, and build a global community of systems thinkers. The System Graph aims to organise data and knowledge across traditional silos like disciplines and scales. Under the agreement, System must maintain its Public Benefit Corporation status for five years and cannot materially change its mission without Wellcome's approval. Founder and CEO Adam Bly said the investment ensures the company's mission remains durable and sustainable whilst driving systems-based research and solutions globally.

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May 7th, 2024
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TAKOMA PARK, Md.--(BUSINESS WIRE)--US Medical Innovations, LLC (USMI) announced today it has received FDA 510k Clearance (K240297) for the Canady Helios Cold Plasma™ (CHCP) Ablation System for the ablation of soft tissue during surgery. The CHCP system consists of the Canady Helios Cold Plasma XL-1000 CP Smart Electrosurgical Generator, Canady Helios Cold Plasma Ablators, Foot Pedal and Trolley Cart. Plasma is the fourth state of matter formed by ionizing neutral gases (i.e. Argon or Helium) combined with electromagnetic fields. The Canady Helios Cold Plasma™ System introduces a novel approach to soft tissue ablation using plasma. The system creates a plasma jet consisting of a pre-programmed, pulsed, non-contact, non-thermal (24 C to 30 C), three-dimensional, Plasma Treated Electromagnetic Field™ (PTEF)

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