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Genentech

Biotech firm creating medicines via R&D

Expert Imaging Lead - Cardiovascular, Renal & Metabolism

Full-TimeUpdated on 10/23/2026
$277.8k - $515.8k/yr+ Discretionary annual bonus
Expert
PhD, MD
Boston, MA, USA+2 moreMore locations: South San Francisco, CA, USA | Basel, Switzerland
In PersonRelocation benefits are not available.
Biology & Biotech

About the job

Requirements
  • Hold a PhD, MD, or equivalent in Radiology, Imaging Science, or a related discipline and have 12+ years of experience in imaging science with strategic impact across clinical trials or drug development programs, or a mix of relevant scientific degree and directly relevant experience.
  • Have broad and deep expertise in relevant imaging methods, including regulatory strategy and AI/ML-enhanced analytics.
  • Demonstrate proven leadership in high-complexity, global projects and governance interactions.
  • Be able to influence senior stakeholders and lead scientific strategy across functions and geographies.
  • Bring deep understanding of the clinical and drug development context; CVRM experience is preferred.
  • Demonstrate proven experience in data science, artificial intelligence/machine learning, digital health, or related technologies and their application in the pharmaceutical industry.
  • Bring broad experience in developing AI-based, data-driven solutions for healthcare.
  • Have proven experience managing projects from concept through deployment and success measurement.
  • Demonstrate a process-oriented mindset, attention to detail, and focus on delivering high-quality results.
  • Demonstrate capacity for independent thinking and ability to make decisions based upon sound principles.
  • Demonstrate strategic agility, problem-solving, and critical thinking skills extending beyond the technical domain.
  • Demonstrate respect for cultural differences when interacting with colleagues in the global workplace.
  • Have excellent verbal and written communication skills, specifically in presentation and writing, and be able to explain complex technical concepts clearly.
Responsibilities
  • Serve as a leading expert in imaging science across the assigned therapeutic area, shaping strategy and leading high-impact, cross-functional initiatives.
  • Translate development needs into robust, scalable imaging endpoints and embed artificial intelligence, machine learning, and advanced analytics where appropriate.
  • Define and direct imaging strategy across multiple programs, influencing DEPCS therapeutic-area digital strategy by anticipating clinical and business needs.
  • Partner with Disease Area Heads, Therapeutic Area Heads, and Franchise Heads to align strategic planning and enhance the people, processes, and technology capabilities needed to improve drug development.
  • Identify disease-area strategy and large-asset-program needs that imaging capabilities and solutions can address, interacting closely with Study Management Teams—including Clinical Science, Biomarker Development, Statistical Science, Clinical Operations, Regulatory, and other functions—to assess trial milestones that can benefit from AI/ML-enabled analytics and medical imaging in trial design, execution, and analysis.
  • Engage Global Development Teams, including the GDT Lead and experts from Clinical Science, Statistical Science, Biomarker Development, and other functions.
  • Engage Asset Teams, including Lifecycle, Commercial, and Access Leads and other relevant stakeholders.
  • Represent DEPCS imaging strategy in functional and enterprise governance, influencing priority-setting, investment decisions, and cross-functional alignment.
  • Anticipate external trends in imaging science, regulatory expectations, and clinical innovation, and incorporate them into strategic planning.
  • Lead the development and lifecycle management of DEPCS AI and medical-imaging-based algorithms, from technology assessments through deployment.
  • Act as a scientific thought leader in imaging across Roche, enabling standardization, interoperability, and reusability of imaging data assets.
  • Lead large global project teams or matrixed initiatives, integrating imaging into the broader development architecture.
  • Serve as a key liaison to external collaborators, academic partners, and vendors, shaping Roche’s role in the imaging science community.
Desired Qualifications
  • Be a recognized leader in the imaging community with external visibility, such as publications or leadership roles.
  • Have experience defining investment cases or shaping functional strategy for imaging innovation.
  • Have familiarity with enterprise-level data architecture and how imaging integrates with multimodal evidence generation.

About the company

Genentech is a biotechnology company focused on researching and developing medicines and therapies to address unmet medical needs. It uses large-scale R&D, with about 13,500 employees and 40 approved medicines; it develops biologics and other therapies marketed through healthcare providers, generating revenue from sales. It differentiates itself with a large patent portfolio (around 20,000 patents) and multiple FDA Breakthrough Therapy Designations, along with a patient-centric approach that weighs access and affordability. Its goal is to advance medical science and deliver high-quality, effective therapies that improve patient health and support the broader medical community.

Company Size

10,001+

Company Stage

Grant

Total Funding

$47.8M

Headquarters

San Francisco, California

Founded

1976

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Simplify's Take

What believers are saying

  • Hillsboro broke ground September 28, 2026 on a $750 million device fill-finish plant.
  • The project adds 250 jobs and strengthens U.S. supply for oncology, neurology, immunology.
  • Roche opened Boston's CVRM Innovation Center on September 17, 2026, expanding discovery capacity.

What critics are saying

  • September 2026 layoffs cut 265 South San Francisco jobs, ending a 40-year plant.
  • June and July 2026 cuts removed 103 gRED roles, signaling continuing research retrenchment.
  • Vabysmo concentration leaves Genentech vulnerable to a retinal franchise reversal by 2027.

What makes Genentech unique

  • Roche-backed Genentech pairs drug discovery with manufacturing, diagnostics, and global commercialization at scale.
  • Vabysmo delivered real-world eye-disease data on September 30, 2026 across 28 countries.
  • The September 24, 2026 Earendil deal shows Genentech still commands elite biotech partners.

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Benefits

  • Performance Bonus
  • Relocation Assistance

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

-3%

2 year growth

-3%
Associated Press
Oct 16th, 2026
FDA approves Genentech's Enspryng as first at-home injection for thyroid eye disease

Genentech, a member of the Roche Group, said the US Food and Drug Administration (FDA) has approved Enspryng for adults with thyroid eye disease (TED). It is the first and only at-home subcutaneous treatment for the condition, and patients or caregivers can give it after training. In the Phase III SatraGO-2 trial, 52.9% of active TED patients on Enspryng had a proptosis response, against 23.4% on placebo. Diplopia fell in 60.7% versus 25.8%. The sister trial, SatraGO-1, missed its primary endpoint at week 24. No new safety signals emerged. The approval, which followed a priority review, is Enspryng's second indication after neuromyelitis optica spectrum disorder in 2020. The FDA is also reviewing it for MOGAD, with a decision expected in January 2027.

The Hindu BusinessLine
Oct 14th, 2026
Biocon inks global patent settlement pact with Genentech for breast cancer drug Pebrilzo.

Biocon inks global patent settlement pact with Genentech for breast cancer drug Pebrilzo. By PTI. Updated - October 14, 2026 at 02:43 PM. Biocon Ltd on Wednesday said it has entered into a global settlement and license agreement with Genentech for breast cancer drug Pebrilzo, its biosimilar to the reference product Perjeta (Pertuzumab). The patent settlement agreement resolves all pending disputes between the two companies across multiple jurisdictions, including the US and Canada, the biopharmaceutical company said in a regulatory filing on Wednesday. Under the terms of the agreement, Biocon is cleared to launch Pebrilzo in the European Union and the United Kingdom in the first quarter of calendar year (CY) 2027, followed by a launch in the US in the third quarter of CY 2028. For other rest of the world markets, the launch is slated for 2026-2028, or earlier under certain circumstances. THIS AD SUPPORTS OUR JOURNALISM. SUBSCRIBE FOR MINIMAL ADS.

PR Newswire
Oct 13th, 2026
2026 Patient Innovators Awards winners announced at Courier Health's annual Summit.

2026 Patient Innovators Awards winners announced at Courier Health's annual Summit. Oct 13, 2026, 09:00 ET Honorees celebrated as biopharma gathered in New York City to chart the future of the patient experience NEW YORK, Oct. 13, 2026 /PRNewswire/ - Courier Health, the leading technology company for managing patient experiences, today announced the winners of the second annual Patient Innovators Awards, which recognize the biopharma teams and leaders going above and beyond to improve patient access, innovation, and overall outcomes. Winners were announced live on October 6th at the third annual Patient Innovators Summit in New York City. The invite-only event brought together Patient Services, Access & Reimbursement, and Commercial IT & Analytics leaders from more than 75 biopharma companies. Together, attendees represented more than 100 disease states and roughly 35 million patients with previously unmet needs. Four teams and one individual were recognized for driving innovation and measurably improving the patient experience: * Rare Disease Champions of the Year: KalVista, a Company of Chiesi Group * Patient Services Team of the Year: Priovant Therapeutics * Field Access Team of the Year: UCB, Inc. * Patient Champion of the Year: Rob Chuba, Alkermes * Patient Innovators of the Year: Bristol Myers Squibb's CAR T-cell therapy Patient Access Support Services (PASS) team "Being named Patient Services Team of the Year is a testament to the team and program we're building," said Lee Liberator, Vice President of Patient Services and Reimbursement at Priovant Therapeutics. "We've built a unique program centered around what patients actually need from us, and we're proud to be recognized for our commitment to innovating and championing a better patient experience." In his opening keynote, Danny Sigurdson, Founder and CEO of Courier Health, described the moment as a fork in the road. As manufacturers take greater internal control of their programs, data ownership, outcomes-based measurement, and AI-enabled workflow innovation have become critical. Organizations that invest in the right foundation will gain greater operational leverage to focus on their core competency - supporting patients and providers - while those that don't will fall further behind. "This year's Patient Innovators Awards winners are proof that a better path, and a brighter future, is already being built," said Danny Sigurdson. "These teams and our individual Patient Champion of the Year aren't afraid to challenge the status quo and rethink how their programs run. They never lose sight of the patient, and it's an honor to recognize their contributions." This year's Patient Innovators Summit featured 11 industry speakers from companies including Alkermes, Beren Therapeutics, Corcept Therapeutics, Compass Pathways, Dyne Therapeutics, Genentech, and Tarus Pharmaceuticals. The audience also heard a powerful firsthand story from Mark Dant, rare disease advocate and Volunteer Executive Director for the Ryan Foundation. About Courier Health Courier Health is a New York City-based technology company on a mission to improve the patient experience for hundreds of millions of people living with a chronic condition or rare disease. The company develops and delivers the fastest-growing patient experience solution for the life sciences industry. Companies that choose Courier Health are achieving double-digit improvements to patient starts, time-to-start and ongoing adherence to life-altering therapies. As host of the invite-only Patient Innovators Summit and publisher of The State of Patient-Centricity in Biopharma report, Courier Health is backed by leading investors, including Oak HC/FT, Norwest and Work-Bench. Follow Courier Health on LinkedIn and learn more at www.courierhealth.com. SOURCE Courier Health

Yahoo Finance
Oct 9th, 2026
FDA approves Tecentriq for stage III colon cancer, cutting recurrence risk by 50%

The FDA has approved Genentech's Tecentriq in combination with a fluoropyrimidine and oxaliplatin for adjuvant treatment of stage III deficient DNA mismatch repair colon cancer. This marks Tecentriq's twelfth indication in the US. The approval follows results from the Phase III ATOMIC study, published in The New England Journal of Medicine. The trial showed Tecentriq plus chemotherapy reduced the risk of disease recurrence or death by 50% compared to chemotherapy alone. The 36-month disease-free survival was 86% with Tecentriq combined with mFOLFOX6, versus 76% with mFOLFOX6 alone. Nearly 25% of colon cancers are diagnosed at stage III. Almost one in three patients with stage III colon cancer experience recurrence within five years. This represents the first approved adjuvant immunotherapy regimen for this patient population.

Pharma Journalist
Oct 7th, 2026
Alector licenses Parkinson's drug program to Genentech for $1.27B.

Alector licenses Parkinson's drug program to Genentech for $1.27B. On Oct 7, 2026 Alector has entered into an exclusive global licensing agreement with Genentech, a member of the Roche Group, to develop and commercialize AL050, an investigational therapy designed to treat a key cause of neurodegeneration linked to Parkinson's disease. Under the agreement, Genentech will receive worldwide rights to AL050, which is designed to address deficiencies in glucocerebrosidase (GCase), an enzyme linked to Parkinson's disease, particularly in people carrying mutations in the GBA1 gene. Alector will receive $100 million upfront from Genentech and could receive up to an additional $1.17 billion in development, regulatory and commercial milestone payments. The company will also be eligible for tiered royalties based on net sales. AL050 combines an engineered version of the GCase enzyme with Alector's proprietary Alector Brain Carrier (ABC) technology. The approach is designed to help the therapy cross the blood-brain barrier and reach the brain, where GCase deficiency can cause harmful lipids to build up in nerve cells. The therapy is intended to break down glucosylsphingosine and glucosylceramide, two lipids that can accumulate when GCase activity is reduced. Alector believes reducing this buildup could help improve cell function and potentially slow the progression of Parkinson's disease. GCase deficiency is increasingly being studied as an important driver of Parkinson's disease. People with GBA1 mutations are at higher risk of developing the disease, although GCase-related mechanisms may also play a role in patients without these mutations. Under the partnership, Genentech will take responsibility for the development, regulatory work, manufacturing and commercialization of AL050 across all potential indications. Alector will retain ownership of its ABC technology and continue using the platform in its wholly owned pipeline. Alector CEO Arnon Rosenthal said the company designed AL050 to address two major challenges in treating GCase deficiency: developing an enzyme with strong and lasting activity and delivering it effectively into the brain. The deal also gives Alector additional resources to advance its other programs. The company said the partnership extends its cash runway into 2029. Alector plans to use these resources to advance its subcutaneously delivered, brain-enabled anti-Aβ antibody program toward multi-cohort clinical data in Alzheimer's disease. The company also plans to move its brain-enabled tau siRNA and alpha-synuclein siRNA programs through IND-enabling studies and toward regulatory filings. The collaboration marks another major step in Genentech's efforts to develop new treatments for Parkinson's disease, while giving Alector the financial support to continue developing therapies targeting neurodegenerative diseases.