Senior Director/Executive Director, Head of Clinical Data Management
Nkarta
Senior Director/Executive Director, Head of Clinical Data Management
Nkarta
Develops NK cell-based cell therapies
About Us
Nkarta is a publicly traded (Nasdaq symbol NKTX), clinical-stage biotechnology company headquartered in South San Francisco, focused on advancing the development of allogeneic, off-the-shelf natural killer (NK) cell therapies to treat autoimmune disease.
Founded in 2015, Nkarta is on a mission to harness the body’s natural killer cells – the immune system’s first responders – to deliver a safe, accessible form of cell therapy to treat B cell-mediated autoimmune diseases. Our vision is to make cell therapy more broadly available to patients by pioneering allogeneic NK cells that can be dosed in outpatient, community health settings.
Nkarta’s engineering process enhances the natural ability of NK cells to fight disease by identifying and eliminating unhealthy cells, including malfunctioning B cells at the root of many autoimmune conditions. Our lead NK cell therapy candidate, NKX019, uses NK cells collected from healthy donors rather than burdening the patient with a blood collection. Using donor-derived cells allows us to develop CAR NK cells off the shelf and on demand.
Nkarta is a people-driven company looking for passionate, collaborative, determined team members galvanized by a paradigm-shifting opportunity to change the cell therapy landscape.
Nkarta is seeking a Senior Director or Executive Director to serve as Head of Clinical Data Management (CDM). This is a hands-on leadership role for an experienced data management executive who will own the strategy, operating model, and quality of clinical data across the NKX019 autoimmune program—from ongoing multi-indication Phase 1/2 studies through potential future pivotal trials and a Biologics License Application (BLA).
NKX019 is being studied in multiple autoimmune indications under rapidly evolving protocols. The Head of CDM will ensure every protocol change is reflected promptly and correctly in the database, that data are analysis-ready for frequent data cuts, and that the function is built to deliver a submission-quality database for future pivotal studies.
Reporting to the VP, Program Management and Head of Clinical Trial Services, this leader will direct Nkarta’s internal data managers and contract staff, hold the biometrics CRO and data vendors accountable for quality and timelines, and partner closely with Clinical Development, Clinical Operations, Biostatistics, Drug Safety, Medical Writing and Regulatory Affairs.
Priority will be given to candidates who can work a hybrid schedule and based in South San Francisco, CA. Travel may be required for health-authority meetings, conferences, vendor oversight, and other business needs.
There are several factors taken into consideration in determining base salary, including but not limited to: job-related qualifications, skills, education and experience, as well as the value of other elements of an employee’s total compensation package. Nkarta also offers an annual discretionary bonus, equity grant(s), medical, dental, vision and life insurance coverage, in accordance with the terms and conditions of the applicable plans. Other benefits include 401K plan, flexible spending account, ESPP, employee assistance program, paid vacation, holiday and personal days, paid parental, pregnancy, and bereavement leave.
The 100+ team members describe working at Nkarta through some of the following comments. While getting better work-life balance and improving communications between groups in an early stage start up environment are two areas on which we are working, here are real, anonymous comments about or regarding why people think Nkarta is a great place to work.
- “People are always open to ideas.”
- “Exceptionally talented, committed, *kind* & supportive team.”
- “The CEO is transparent and honest with expectations for the whole company. There is genuine care amongst the leadership team for their peers and employees. I believe this is unique.”
- “Not to sound corny, but the emphasis on people as a valuable resource is something I recognize doesn't often exist elsewhere, and it's here in ample supply, which is great.”
- “It's the first place that I've worked where the executive team truly values the employees. It's a pretty amazing thing not to hear that employees can be replaced with someone new. Institutional knowledge is understood.”
- “We have a very diverse team with executives that are friendly and accessible.”
- “Smart and dedicated colleagues. Mission to make a difference in patients’ lives. Empower us with tools needed to succeed. Open and transparent culture. Transparent leadership.”
To learn more about our work at Nkarta and the career opportunities that will drive us forward to serve patients, please visit the company’s website at https://www.nkartatx.com.
Pay Range 285000 - 330000 USD
Nkarta develops next-generation cell therapies using natural killer (NK) cells to treat cancer and autoimmune diseases. The company expands and enhances NK cells with proprietary technology to improve their ability to locate and destroy tumor cells, then uses these optimized cells as therapeutic products. Its approach relies on research and development, clinical trials, and eventual commercialization, with revenue coming from partnerships, licensing agreements, and future product sales. Nkarta differentiates itself by leveraging its focused NK cell expansion and optimization capabilities to improve efficacy, tolerability, and accessibility of cell therapies. The company aims to make potent, well-tolerated NK cell therapies more broadly available to patients in need.
Explore more opportunities at Nkarta