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Amgen

Makes biotech medicines for serious illnesses

Associate Scientist - Digital Discovery, Antibody Bioinformatics

Quantitative Biology & BiostatisticsConfirmed live in the last 24 hours
Full-timeBurnaby, BC, CanadaCA$92.5k - CA$125.1kIn-person

About the Job

Requirements

  • A Master's degree and at least 1 year of relevant experience, or a Bachelor's degree and at least 3 years of relevant experience, in Biological Sciences, Biochemistry, Molecular Biology, Immunology, Bioinformatics, Computational Biology, or a related field.
  • Hands-on wet-lab or experimental research experience in molecular biology, immunology, biologics or antibody discovery, genomics, next-generation sequencing, protein characterization, or a related life-science discipline.
  • Training or experience in bioinformatics, computational biology, scientific informatics, or biological data analysis through coursework, research projects, internships, or professional experience.
  • Working knowledge of R and/or Python for biological data analysis, visualization, and scripting.
  • Experience working with complex experimental datasets and associated metadata, including data curation, integration, quality control, and documentation.
  • Exposure to next-generation sequencing, immune repertoire, single-cell, flow cytometry, or other high-dimensional biological datasets.
  • Familiarity with Linux or command-line environments, reproducible analysis practices, cloud or high-performance computing environments, and/or laboratory informatics systems such as Benchling, electronic laboratory notebooks, or laboratory information management systems.
  • Strong communication, organization, and collaboration skills, with an interest in working across experimental and computational disciplines.

Responsibilities

  • Run established antibody discovery computational workflows, assess sequencing and data quality, and support downstream analysis of antibody repertoires and candidate sequences.
  • Analyze B-cell receptor repertoire, next-generation sequencing, single-cell, protein, and associated antibody discovery datasets to characterize sequence diversity, identify antibody candidates, and support discovery decisions with guidance from senior team members.
  • Develop R and/or Python scripts, analytical tools, reports, and visualizations to automate downstream B-cell receptor sequencing analyses and enable scientists to explore, interpret, and communicate discovery results.
  • Organize, curate, and integrate B-cell receptor sequencing, antibody screening, and associated experimental data and metadata to support downstream analysis, data mining, and reuse across antibody discovery programs.
  • Work with wet-lab scientists to ensure sample, sequencing, and antibody discovery data are captured, connected, and structured to support downstream analysis and traceability, including within platforms such as Benchling.
  • Apply hands-on knowledge of molecular biology, immunology, biologics discovery, genomics, next-generation sequencing, and related laboratory workflows to interpret data within its experimental context.
  • Partner with wet-lab and computational scientists to investigate data-quality issues, improve experimental-to-computational handoffs, and help ensure experiments generate robust, analysis-ready data.
  • Communicate analytical findings and recommendations through clear visualizations, concise scientific summaries, and collaborative problem-solving.

Desired Qualifications

  • Experience with SQL.
  • Familiarity with tools such as Cell Ranger, Seurat, Scanpy, FlowJo, Bioconductor, or comparable platforms.

About the Company

Amgen

Makes biotech medicines for serious illnesses

Amgen develops and makes biologic medicines, which are drugs built from proteins and antibodies grown in living cells, for serious conditions such as heart disease, cancer, and bone loss. Its anemia drug Epogen, approved in 1989, became one of the biotechnology industry's first blockbuster medicines. Amgen grows these drugs in large tanks called bioreactors, and its products include the cholesterol drug Repatha, the bone-building drug Evenity, and the severe asthma drug Tezspire. It earns money by selling these medicines, mostly through large drug wholesalers that supply hospitals and pharmacies. Amgen was founded in 1980 and is based in Thousand Oaks, California.

Company size
10,001+
Company stage
IPO
Headquarters
Thousand Oaks, CA
Founded
1980

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