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Biosphere

Provides industrial bioreactors for sustainable bioproducts

Director Technology Development

Process EngineeringConfirmed live in the last 24 hours
Full-timeOakland, CA, USAIn-person

About the Job

Requirements

  • Have led a complex, multidisciplinary technical team developing and scaling new process technology in biotech, chemicals, materials, energy, water, or another process industry.
  • Have process engineering experience including mass and energy balances, unit operations, heat and mass transfer, scale-up, and techno-economic analysis.
  • Be fluent in experimental design and applied statistics, including designed experiments, hypothesis testing, sample size and power, and reliability or rare-event analysis.
  • Write and present clearly to engineers and funders.

Responsibilities

  • Own day-to-day R&D priorities, experimental decisions, and delivery within agreed budgets, taking increasing ownership of high-risk technical work as delivery progresses.
  • Lead and grow the R&D team by setting priorities, coaching, reviewing data, and hiring as the work requires.
  • Lead development and validation of assigned technologies, agree on requirements and acceptance criteria with the Principal Engineer and capital projects team, and hand off into plant design and commissioning.
  • Execute roadmap milestones by taking new reactor technologies and subsystems from proof of concept to validated designs, including pilot-scale reactors and next-generation reactor prototypes for government-funded programs.
  • Deliver validated designs and specifications for the 20,000-liter line, and support installation and commissioning.
  • Lead assigned funded research projects through delivery and technical reporting, work with project managers, and contribute to proposals when aligned with priorities and capacity.
  • Make process and techno-economic decisions, including evaluating alternatives such as replacing specialty cleaning chemical with dilute commodity caustic or changing cleaning-cycle temperature.
  • Set standards for experimental design and statistics by defining what each test must show, the number of runs, and analysis methods, including for rare events such as contamination.
  • Build tools to track experiments and characterize failures.
  • Manage the R&D portfolio by assigning program owners, budgets, milestones, and next decisions; ranking work by value, remaining cost, and delivery risk; stopping discretionary work that no longer justifies its cost; and escalating changes to contractual commitments.
  • Agree on a delivery plan for the R&D portfolio with the management team, including priorities, owners, milestone dates, acceptance criteria, and dependencies with the plant team.
  • Ensure roadmap technologies have validated designs, test data, and acceptance criteria incorporated into the demonstration plant design.
  • Ensure funded research projects meet milestones and budgets without delaying priority commitments.
  • Enable routine R&D decisions within the team and bring strategy, major spending, or new commitments to leadership with supporting data, economics, and recommendations.
  • Run the development portfolio independently and provide evidence-backed recommendations for future work.

Desired Qualifications

  • Experience with bioreactor or fermentation equipment development, pilot-scale reactor design, and scale-up.
  • Experience with cleaning and sterilization (CIP, SIP, sterility validation) and hygienic design (ASME BPE, EHEDG).
  • Experience with first-of-a-kind process plants or capital projects.
  • Experience with government-funded R&D programs.
  • Experience with instrumentation and controls.

About the Company

Biosphere

Provides industrial bioreactors for sustainable bioproducts

Biosphere develops and integrates bioreactor technology to power industrial biomanufacturing for global commodities like food, fuel, and materials. Its bioreactors are designed to be deployed inside large-scale production facilities, with the company providing hardware, integration work, and ongoing services to customize and optimize production. It differentiates itself by pairing advanced bioreactor technology with platform integration for broad industrial adoption, offering concrete licensing and deployment options to move away from monocropping, factory farming, and petroleum refining. The goal is to make large-scale bio-based production financially viable and environmentally sustainable on a global scale.

Company size
11-50
Company stage
Seed
Total funding
$8.8M
Headquarters
Oakland, CA
Founded
2022

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