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Stoke Therapeutics

Develops targeted gene upregulation therapies

Associate Director / Director - Technology Services

System AdministrationConfirmed live in the last 24 hours
Full-time

About the Job

Requirements

  • A bachelor's degree in computer science, information systems, or a related field, or equivalent experience.
  • At least 10 years of progressive IT operations and infrastructure experience in biotech, healthcare, or managed-services environments, including experience leading an IT team or function.
  • Strong hands-on background in Microsoft 365, Entra ID (Azure AD), Intune or equivalent endpoint management for Windows and macOS, networking (switching, Wi-Fi, firewalls), and cloud infrastructure.
  • Experience with office build-outs, relocations, or comparable infrastructure projects, including network and audio/visual technology.
  • ITIL-based service management experience, including building service-level agreements and support models for a distributed workforce.
  • Experience operating in a regulated environment, including SOX IT general controls and GxP infrastructure qualification, and working with an MDR/SOC provider and external security assessments.
  • Vendor and managed service provider management and budgeting experience.
  • Service-minded approach, calm under pressure, and ability to communicate with technical and non-technical colleagues.

Responsibilities

  • Lead and develop the Technology Services team, including the help desk manager, systems administration, help desk staff, and contractors, while setting service standards, service-level agreements, and the on-site support model.
  • Own infrastructure and end-user technology, including network and Wi-Fi, identity and endpoint management, Microsoft 365 and collaboration tools, conference rooms and audio/visual technology, printing, mobile devices, cloud infrastructure, and backup and disaster recovery.
  • Deliver IT for the Waltham move in partnership with Facilities & Engineering, including network, Wi-Fi and audio/visual build-out, access control and building systems integration, cutover planning, day-one support, and decommissioning of the Bedford site.
  • Own laboratory IT infrastructure, including instrument connectivity, lab network segmentation, and lab endpoint support, in coordination with Facilities and the Scientific Applications lead, who owns research applications.
  • Deliver field force readiness ahead of launch for Sales & Marketing and Field Medical, including device provisioning and mobile device management (Intune/Autopilot), remote onboarding, field support hours, and self-service, scaled to the 2027 hiring plan.
  • Serve as the operational counterpart to Information Security and the MDR provider by executing endpoint protection, patching, and access provisioning to defined standards; triaging and remediating infrastructure and endpoint findings; tracking remediation from external security assessments and audits through closure; and maintaining ITGC evidence.
  • Partner with Information Security on operational IT policies and standards, including acceptable use, asset lifecycle, backup and disaster recovery, and endpoint and access provisioning procedures; keep them current, documented, and audit-ready, and ensure resilience with no single points of failure across operations.
  • Deploy, provision, and support enterprise AI productivity tools for end users, including configuration, access, and staff enablement, within the governance set by the CIO’s Data & AI function and Information Security.
  • Support infrastructure qualification and controls for GxP- and SOX-relevant systems with the Clinical & Regulatory Systems and Enterprise Applications teams.
  • Manage vendors and managed service providers, contracts, hardware and software lifecycle, asset inventory, and the Technology Services budget.
  • Run incident, problem, and change management; define and report operational metrics and service levels.
  • Contribute to IT strategy and standards as a member of the IT leadership team.

Desired Qualifications

  • ITIL, Microsoft, Cisco/Meraki, or comparable certifications.
  • Experience supporting a commercial field team or product launch, and experience with laboratory IT and scientific instrument connectivity.
  • Experience rolling out and supporting enterprise AI productivity tools, such as Microsoft Copilot or Claude, for end users.

About the Company

Stoke Therapeutics

Develops targeted gene upregulation therapies

Stoke Therapeutics develops therapies for severe genetic diseases caused by loss of function in a single gene, aiming to restore missing proteins by upregulating protein expression. Its main product approach relies on the TANGO (Targeted Augmentation of Nuclear Gene Output) platform, which delivers precise, durable, and controllable upregulation of gene expression across a range of tissues to re-create the missing protein. Compared with many biotech firms, Stoke centers on upregulating endogenous gene output rather than replacing genes or adding new ones, and focuses on disease-modifying treatments for rare disorders with unmet medical needs. Revenue comes from partnerships, licensing agreements, and, ultimately, commercialization of its therapies. The company’s goal is to provide targeted, durable treatments that address the underlying genetic deficiency and improve outcomes for patients with limited options.

Company size
201-500
Company stage
IPO
Headquarters
Bedford, TX
Founded
2014

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