Full-Time

Global Trade Compliance Senior Manager

Updated on 9/12/2026

Amgen

Amgen

10,001+ employees

Biotech company creating biologic medicines

Compensation Overview

$133.1k - $180.1k/yr

+ Annual bonus + Stock-based long-term incentives

Tampa, FL, USA + 1 more

More locations: Thousand Oaks, CA, USA

Hybrid

Flex commuter/hybrid work model applies at each listed location.

Bachelor's, Master's, PhD, Associate's

Category
Risk & Compliance (1)

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Requirements
  • A Doctorate degree and 2 years of experience in compliance or screening operations, risk management, regulatory affairs, audit, law, or a related field; or a Master's degree and 4 years of such experience; or a Bachelor's degree and 6 years of such experience; or an Associate's degree and 10 years of such experience.
  • Experience as a trade compliance subject matter expert in a multinational company.
  • Strong knowledge of Bureau of Industry and Security and Office of Foreign Assets Control sanctions regulations, the 50 Percent Rule, and other global restricted-party screening requirements.
  • Experience conducting ownership due diligence and ultimate beneficial ownership investigations, including analysis of complex direct and indirect ownership structures.
  • Proficiency with sanctions and trade compliance platforms such as Dow Jones, Descartes, MK Denial, Sayari, Kharon, SAP Global Trade Services, Oracle Global Trade Management, or comparable systems.
  • Experience conducting and managing investigations, incident management, and remediation plans.
  • Ability to synthesize, analyze, and communicate complex compliance data and concepts to diverse audiences.
  • Ability to leverage artificial intelligence and advanced analytics for compliance monitoring, risk assessment, and data-driven decision making.
  • Strong critical thinking, writing, negotiation, presentation, project management, and organizational skills.
  • Ability to think strategically, translate strategy into action plans, prioritize competing demands, resolve conflict, meet deadlines, and operate independently.
  • Demonstrated ability to build effective relationships across departments and geographies, influence all levels of staff and management, and work successfully in a global matrix.
  • High ethical standards, professional integrity, maturity, flexibility, and sensitivity to diverse groups and perspectives.
Responsibilities
  • Lead key elements of Amgen's global trade compliance program, providing strategic guidance across sanctions, export controls, restricted-party screening, clinical valuation, and other international trade compliance matters.
  • Own the enterprise framework for screening counterparties, transactions, and ownership structures under the U.S. Department of the Treasury's Office of Foreign Assets Control 50% rule, the U.S. Department of Commerce's Bureau of Industry and Security 50% rule, and other applicable global regulatory authorities.
  • Serve as the primary escalation point for high-risk screening alerts and complex ownership determinations.
  • Lead enhanced due diligence activities and prepare risk assessments and recommended operational actions in partnership with the legal team, business partners, and cross-functional stakeholders.
  • Lead the global clinical trial customs valuation program, including maintaining valuation methodologies, coordinating the annual true-up process, and partnering with stakeholders to ensure compliance with applicable clinical customs valuation requirements.
  • Leverage automation, artificial intelligence, advanced analytics, and digital technologies to improve efficiency, scalability, and risk detection.
  • Support additional trade compliance initiatives and special projects across the Global Trade Compliance organization as business priorities and global regulations evolve.
  • Provide trade compliance support for strategic business initiatives, acquisitions, product launches, supply chain changes, and other enterprise projects.
  • Lead multiple complex initiatives simultaneously in a dynamic global environment.
  • Foster a culture of ethics, integrity, accountability, and continuous improvement throughout the organization.
Desired Qualifications
  • Healthcare or life sciences experience is preferred.

Amgen develops medicines that treat serious illnesses by using biologic therapies made from living cells. These therapies are designed to target specific disease processes, such as cancer, cardiovascular disease, and autoimmune conditions, and are produced through biotechnology methods that create proteins or antibodies. Amgen’s products are sold to patients and healthcare providers worldwide, with revenue funding ongoing research and development to discover new treatments. The company stands out by focusing on biologic medicines at a large scale and maintaining a steady pipeline of potential therapies across multiple disease areas, supported by global manufacturing and a commitment to bringing therapies to patients. Its goal is to improve patient outcomes by discovering and delivering new, effective treatments while reinvesting a significant portion of earnings into research and development.

Company Size

10,001+

Company Stage

IPO

Headquarters

Thousand Oaks, California

Founded

1980

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Simplify Jobs

Simplify's Take

What believers are saying

  • Q2 2026 revenue rose 10% to $10.1 billion, and guidance increased to $38.2 billion-$39.4 billion.
  • Repatha sales jumped 37% to $953 million in Q2 2026, with U.S. prescriptions up 50%.
  • MariTide advanced through multiple Phase 3 studies in 2026, supporting a 2027 obesity catalyst.

What critics are saying

  • Prolia sales fell 32% in Q2 2026 as biosimilars attack Amgen’s legacy cash cow.
  • FDA proposed withdrawing Tavneos in April 2026, signaling regulatory risk from integrity and efficacy issues.
  • Olpasiran now faces Novartis pelacarsen failure scrutiny; a negative 2028 OCEAN(a) readout would crush Lp(a) upside.

What makes Amgen unique

  • Repatha, Evenity, and Uplizna diversify Amgen beyond one blockbuster, per August 2026 sales.
  • MariTide targets quarterly or eight-week dosing, unlike Lilly and Novo Nordisk weekly injections.
  • Amgen’s 2027 Hyderabad Science and Innovation Center expands AI-enabled drug discovery globally.

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Benefits

Professional Development Budget

Conference Attendance Budget

Company News

Yahoo Finance
Sep 10th, 2026
Amgen trades at 17x 2026 earnings, but forecast margin expansion assumes MariTide success

Amgen trades at $393 per share, representing a trailing multiple of 23.3 times adjusted earnings. The biotech faces declining sales from Prolia and XGEVA, down 33% year-over-year to $1.1 billion in Q2 2026, due to biosimilar competition. Six key growth medicines grew 26% year-over-year, accounting for nearly 70% of Q2 product sales. Analysts forecast the forward multiple at 17.0 times for fiscal 2026 and 16.1 times for 2027. However, consensus assumes expanding profit margins whilst Amgen increases spending. Non-GAAP research spending is set to grow in high single digits for 2026, funding nine Phase III trials for MariTide, its obesity treatment candidate. Management warned of meaningful operating expense increases in Q3 2026. The valuation depends on margin expansion materialising during this investment phase.

Yahoo Finance
Sep 7th, 2026
Amgen's $437 olpasiran bet faces higher bar after Novartis Lp(a) drug fails Phase 3 trial

Amgen faces heightened scrutiny for its experimental heart drug olpasiran after rival Novartis's pelacarsen failed to reduce major cardiovascular events in a Phase 3 trial, despite successfully lowering lipoprotein(a) levels. The setback demonstrates that improving laboratory biomarkers may not translate to better patient outcomes. Amgen's OCEAN(a) outcomes study has enrolled 7,297 participants and is tracking heart-related deaths and procedures over roughly five years. While olpasiran uses a different design and may target different patients, pelacarsen's failure removes assumptions about the commercial value of lowering Lp(a). Amgen's shares traded at $437.23, sitting 19.54% above its estimated fair value of $365.76. The company reported $10.1 billion in second-quarter revenue and $3.5 billion in free cash flow.

Yahoo Finance
Sep 1st, 2026
Amgen's Repatha hits $953M in Q2 sales, up 37% as Cramer calls it "biggest market of all time

Jim Cramer highlighted Amgen's cholesterol drug Repatha as a key driver behind the company's 31% year-to-date rally, calling it an overlooked catalyst by Wall Street. The injectable treatment, administered every two weeks, reduces death risk by 20% in patients at high risk for heart attack or stroke. Repatha generated $953 million in second-quarter sales, up 37% year-over-year. US new prescriptions surged over 50%, split evenly between cardiologist use and primary-care adoption for high-risk patients. Cramer noted the drug works against diabetes and high cholesterol, though insurance reimbursement has posed challenges. Amgen trades at a forward PE of 19, compared to Eli Lilly's 32, whilst outperforming Lilly's 10% gain this year. Repatha is one of six growth drivers representing nearly 70% of Amgen's product sales. The company raised full-year revenue guidance to $38.2-$39.4 billion.

Yahoo Finance
Aug 19th, 2026
Amgen surges 3.5% to $440 as healthcare stocks hit record high on strong Q2 results

Amgen shares jumped 3.5% to $440.08 on Wednesday as healthcare stocks reached record highs. The biotech company reported second-quarter revenue of $10.1 billion, up 10%, whilst GAAP earnings surged 65% to $4.37 per share. Twenty-two of Amgen's medicines posted double-digit sales growth, with seventeen products generating over $1 billion in annualised sales. Six key growth products climbed 26% and now account for nearly 70% of product revenue. The rally came as investors rotated into healthcare following excitement around Merck and Moderna's melanoma breakthrough. However, Amgen now trades at a 19% premium to its fair value estimate of $365.04, putting pressure on execution as some products like Prolia face headwinds.

Yahoo Finance
Aug 14th, 2026
Amgen and Regeneron emerge as GLP-1 investment alternatives beyond Eli Lilly and Novo Nordisk

Amgen and Regeneron could benefit from surging demand for GLP-1 drugs, which traditionally treated diabetes but now address obesity and obstructive sleep apnea. Amgen's stock is up 27% this year, with second-quarter revenue rising 10% year-over-year to $10.1 billion. The company is testing MariTide, an investigational GLP-1 medicine, in phase 3 studies for weight management and diabetes. MariTide could be administered monthly or less frequently, offering a convenience advantage over current daily or weekly treatments. Regeneron is also positioned to capitalise on the GLP-1 market expansion. Both companies present alternatives to current market leaders Eli Lilly and Novo Nordisk for investors seeking exposure to the growing GLP-1 drug category.