Manager – Immunohistochemistry - Immunohistochemistry, and Histology

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Overview

The Manager of Immunohistochemistry (IHC) and Histology is responsible for the daily operational oversight of technical staff performing IHC, ISH, immunofluorescence, surgical histology, special stains, tissue processing, embedding, microtomy, frozen section procedures, and Developmental Histology/Tissue Microarray Archive (DH/TMA) services within Anatomic Pathology and provides oversight for department’s clinical Anatomic Pathology lab USPs.

This position ensures high-quality technical performance, regulatory compliance (CAP, CLIA, State, and Joint Commission), efficient workflow, and exceptional customer service for both clinical and research stakeholders. The Manager reports to the Senior Manager of AP and collaborates closely with faculty, residents, fellows, students, researchers, and laboratory leadership to maintain excellence in diagnostic and research support services.

In addition to overseeing clinical histology and immunohistochemistry operations, the Manager manages the Developmental Histology/Tissue Microarray Archive facility, serving as a primary resource for investigators and research personnel. Responsibilities include project consultation, tissue microarray development, archive management, client support, and coordination with internal and external partners to ensure successful completion of research initiatives.

The Manager is expected to maintain operational flexibility and technical competency to provide cross-coverage within both Immunohistochemistry and Histology services. Training and competency assessment will be provided as needed to ensure safe and compliant cross-coverage.

The hours for this position will be 10:00 AM to 6:00 PM.

Operational Supervision

• Supervises day-to-day workflow of the IHC, Histology, and DH/TMA laboratories.
• Provides oversight for department’s clinical AP lab USPs.
• Oversees IHC staining, ISH staining, immunofluorescence, special stains, frozen sections, embedding, microtomy, and tissue processing.
• Monitors turnaround times, workload distribution, project timelines, and production standards.
• Addresses technical and operational issues and escalates concerns as appropriate.
• Performs technical procedures as necessary to support workflow continuity.
• Oversees operations of the Developmental Histology/Tissue Microarray Archive facility, ensuring efficient service delivery and project completion.

Research Support and Client Services

• Serves as the primary point of contact for researchers and clients, including principal investigators, faculty, fellows, residents, postdoctoral associates, graduate students, and staff.
• Consults with clients regarding histology, immunohistochemistry, and tissue microarray methodologies to determine the most appropriate techniques for research projects.
• Monitors client projects to ensure quality standards and established deadlines are met.
• Creates tissue microarrays (TMAs), specialized slides, and other customized histology products to support research activities.
• Responds to client inquiries and provides guidance regarding project scope, specimen requirements, and laboratory services.
• Provides technical support and direction to staff regarding client orders and research requests.​

Archive Management and Clinical Collaboration

• Oversees the research slide and tissue block archive and supervises archive-related activities.
• Ensures accurate organization, maintenance, retrieval, and preservation of archived specimens and related records.
• Assists in locating and retrieving slides and blocks from research collections to support clinical operations and patient care activities.
• Collaborates with clinical and research stakeholders to ensure timely access to archived materials.

Cross-Coverage & Workforce Flexibility

• Maintains competency to provide cross-coverage in both IHC and Histology sections as required.
• Supports laboratory operations during staffing shortages, high-volume periods, or emergent situations.
• Participates in structured cross-training programs to maintain operational resiliency.
• Ensures all cross-coverage duties are performed in accordance with CAP, CLIA, State, Joint Commission, and institutional competency requirements.

Regulatory & Quality Compliance

• Ensures compliance with CAP, CLIA, State, and Joint Commission standards.
• Oversees documentation of quality control, corrective actions, validations, and maintenance logs.
• Assists in validation of new antibodies, assays, procedures, and instrumentation.
• Conducts annual review of laboratory procedures and standard operating procedures.
• Participates in quality assurance initiatives and prepares quality and workload reports.

Staff Supervision & Development

• Supervises exempt and non-exempt technical staff.
• Assigns daily work and monitors workload distribution.
• Conducts and documents competency assessments per regulatory requirements.
• Ensures documentation of training, onboarding, and continuing education.
• Participates in hiring, performance evaluations, coaching, and corrective actions in collaboration with leadership.
• Promotes cross-training to enhance team flexibility and operational continuity.

Equipment, Systems & Resource Oversight

• Monitors functionality and preventive maintenance of laboratory equipment.
• Ensures service contracts and maintenance documentation are maintained.
• Oversees inventory levels and supply ordering for clinical and research operations.
• Ensures compliance with laboratory safety, chemical storage, and hazardous waste procedures.
• Supports evaluation and implementation of new technologies and instrumentation.
• Partners with ITS and laboratory stakeholders to support enhancements, maintenance, and optimization of the eHisto system to improve operational efficiency and customer experience.
• Collaborates with other YPTS divisions, CTTS, and TPA to support departmental initiatives and operational needs.

Administrative & Financial Support

• Assists leadership with supply utilization monitoring and cost-efficiency initiatives.
• Provides workload, utilization, and performance data for reporting purposes.
• Ensures accurate use of laboratory information systems, eHisto, and instrumentation software.
• Supports continuous quality and process improvement initiatives.
• Performs other duties as assigned.

Required Skills and Abilities

1. Strategic leadership and management skills with a focus on departmental functions.

2. Exceptional communication skills, both verbal and written.

3. Strong analytical, critical thinking, organizational, time management, and problem-solving abilities.

4. Expertise in overseeing and implementing communications strategies and managing public relations.

5. Proficiency in managing administrative teams and optimizing office productivity.

Preferred Skills and Abilities

1. Advanced degree and experience in academic or executive administration.

2. Knowledge of federal and state regulations, especially in clinical trials and human research.

3. Proficiency with project management software and understanding of graphic design principles.

4. Demonstrated excellence in communication, leadership, and collaboration within diverse teams.

5. Strong familiarity with budget management, financial planning, and compliance with regulations.

Principal Responsibilities

1. Reviews and determines staffing needs, job posting requirements, salary guidelines, and labor agreement interpretations for exempt and non-exempt staff in one or more functional department of the University. 2. Manages the administrative support needs for exempt and nonexempt staff and provides recommendations, improvements, solutions and assistance as needed. 3. Manages and monitors technology needs, conducts inventory, and system requirements for the assigned departments. 4. Develops and prepares budgets, financial forecasts, and financial analyses and the actual vs. budgeted performance reports for the departments. 5. Manages the use of facilities in one or more departments including office space, work stations, equipment, and office supplies. 6. Manages administrative support for activities of one or more departments to ensure timely completion of projects. 7. Manages and coordinates training sessions for assigned departments when new policies or practices are adopted. 8. Ensures compliance with University and federal regulations as they apply to the assigned departments. 9. Identifies, plans, and develops administrative policies for the assigned departments. 10. Assists in reviewing and implements University and departmental policies as they pertain to the administrative functions of the assigned department. 11. Assesses and makes recommendations regarding staff development and staffing levels. 12. Monitors, develops, plans, and executes systematic research on user requirements through such mechanisms as surveys, interviews, focus groups and competitive analysis. 13. Manages a staff of exempt and non-exempt employees. 14. May perform other duties as assigned. Required Education and Experience Bachelor’s Degree in related field and 5 years of experience or an equivalent combination of education and related experience.

Job Posting Date

11/12/2026

Job Category

Manager

Bargaining Unit

NON

Compensation Grade

Administration & Operations

Compensation Grade Profile

Manager; Program Leader (25)

Salary Range

$82,000.00 - $131,500.00

Benefits

A general description of the benefits to be offered with this Managerial & Professional position is available at:

Yale Benefits

Time Type

Full time

Duration Type

Staff

Work Model

On-site

Background Check Requirements

All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks basedon the position description and job requirements. All offers are contingent upon the successful completion of the background check. For additional information on the background check requirements and process visit "Learn about background checks" under the Applicant Support Resources section of Careers on the It's Your Yale website.

Health Requirements

Certain positions have associated health requirements based on specific job responsibilities. These may include vaccinations, tests, or examinations, as required by law, regulation, or university policy.

Posting Disclaimer

Salary offers are determined by a candidate’s qualifications, experience, skills, and education in relation to the position requirements, along with the role’s grade profile and current internal and external market conditions.

The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the position. Employees will be assigned specific job-related duties throughtheir hiring department.

The University is committed to basing judgments concerning the admission, education, and employment of individuals upon their qualifications and abilities and seeks to attract to its faculty, staff, and student body qualified persons from a broad range of backgrounds and perspectives. In accordance with this policy and as delineated by federal and Connecticut law, Yale does not discriminate in admissions, educational programs, or employment against any individual on account of that individual’s sex, sexual orientation, gender identity or expression, race, color, national or ethnic origin, religion, age, disability, status as a special disabled veteran, veteran of the Vietnam era or other covered veteran.

Inquiries concerning Yale's Policy Against Discrimination and Harassment may be referred to the Office of Institutional Equity and Accessibility (OIEA).

Note

Yale University is a tobacco-free campus.