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Bachem

Develops and manufactures peptides and oligonucleotides

Director Technical Operations

Bioprocess & BiomanufacturingConfirmed live in the last 24 hours
Full-timeVista, CA, USAIn-person

About the Job

Requirements

  • A Bachelor's degree in Chemical Engineering, Biochemical Engineering, Pharmaceutical Sciences, Chemistry, or a related scientific or engineering discipline with equivalent relevant experience, or a Master's degree in one of those fields or a related scientific or engineering discipline.
  • At least 8 years of GMP experience in pharmaceutical, biotech, CDMO, process development, manufacturing science, technical operations, or manufacturing environments, with exposure to clinical and commercial manufacturing.
  • At least 3 years of leadership experience in Technical Operations, manufacturing science, process development, or related technical functions, including leadership of technical and cross-functional teams, technology transfers, process optimization, validation support, technical documentation, and lifecycle management activities.
  • Strong knowledge of GMP, quality systems, regulatory requirements, validation principles, process safety, and inspection readiness expectations.
  • Strong analytical, troubleshooting, decision-making, and problem-solving skills, with familiarity with Lean Six Sigma and operational excellence methodologies.
  • Ability to lead and develop technical teams and collaborate effectively with cross-functional stakeholders.
  • Strong project management and communication skills, with the ability to influence stakeholders and drive execution.
  • Understanding of budgeting, resource planning, COGS improvement opportunities, and business considerations that affect Technical Operations.
  • Ability to work effectively within a matrix organization and collaborate across multiple functions and sites.
  • Demonstrated ability to lead change, improve processes, and support implementation of new technologies and digital tools.
  • Strong technical understanding of manufacturing processes, equipment, technology transfer, product stewardship, lifecycle management, standard operating procedures, qualification protocols, enterprise resource planning/manufacturing execution systems, and technical documentation.

Responsibilities

  • Ensure technical support for clinical and commercial products through technology transfer, process monitoring, troubleshooting, product stewardship, validation support, lifecycle management, and manufacturing readiness activities.
  • Lead technology transfer activities, including internal transfers and transfers from client sites, ensuring effective planning, risk assessment, process understanding, validation readiness, and technical documentation.
  • Lead efforts to improve manufacturing efficiency and process robustness through troubleshooting, root cause investigations, change controls, corrective and preventive actions, data analysis, and process optimization initiatives.
  • Serve as a member of the site leadership team, representing Technical Operations in site initiatives, operational readiness activities, and alignment with global technical standards.
  • Lead technical support for manufacturing activities, new product introductions, process improvements, and site operational initiatives in partnership with Manufacturing, Quality, Engineering, Supply Chain, Research and Development, and Project Management.
  • Support development and implementation of technical capabilities, automation and digitalization initiatives, and platform technologies aligned with site and business needs.
  • Coach, develop, and retain technical talent by promoting knowledge sharing, continuous improvement, accountability, and professional development.
  • Partner with cross-functional stakeholders to support technical strategies, risk management activities, technology transfer execution, operational excellence initiatives, and cost of goods sold improvement efforts.
  • Support regulatory inspections, audits, validation activities, and inspection readiness efforts by providing technical expertise and documentation support.
  • Promote process safety, technical stewardship, and compliance with company policies, procedures, and good manufacturing practice requirements.

About the Company

Bachem

Develops and manufactures peptides and oligonucleotides

Bachem provides development and manufacturing of peptides and oligonucleotides for research, clinical development, and commercial products. Its offerings include custom synthesis and scale-up production, analytical testing, and related services across the drug development spectrum. Customers work with Bachem by specifying desired sequences and specifications, after which Bachem designs, synthesizes, and quality-controls the peptides or oligonucleotides and delivers them in appropriate scales and formats. The company differentiates itself through more than five decades of experience, a global footprint with sites in Europe, the US, and Asia, and an integrated set of services spanning discovery support to commercial manufacturing. Its goal is to help pharmaceutical and biotechnology companies advance peptide- and oligonucleotide-based therapies by providing reliable, scalable, and well-supported manufacturing and development capabilities.

Company size
1,001-5,000
Company stage
IPO
Headquarters
Bubendorf, Switzerland
Founded
1971

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