Full-Time
Scientist I/II
Analytical Development
Confirmed live in the last 24 hours
Generates innovative biotech health and sustainability solutions
Mid
Cambridge, MA, USA
- BS (+8 years experience), MS (+6 years experience), or PhD (+2 years experience) in biochemistry, analytical chemistry, chemical engineering, biophysics, or related discipline
- Expertise with methods specifically for LNP and nucleic acid (mRNA/RNA) characterization, especially particle (size) characterization
- Experience with biochemical and/or biophysical (e.g., particle size) methods: HPLC/UPLC, LC-MS/MS, LC-CAD, CE, UV-Vis, DLS, NTA
- Exposure to cell-based, immunoassay (e.g., ELISA), and molecular (e.g., PCR) methods
- Background with analytical method development with line-of-sight to CMC/GMP
- Proven ability to work both independently and in cross-functional teams in a fast-paced, entrepreneurial environment
- Ability to troubleshoot complex problems
- Highly self-motivated and comfortable delivering against challenging commitments
- Excellent organizational and communication skills
- Design and optimize novel methods to characterize nucleic acid LNP composition, structure, and function; particularly for the delivery of RNA molecules
- Develop approaches using biophysical, biochemical, immunoassays, cell-based assays, and molecular assays with line-of-sign to GMP
- Provide technical guidance and hands-on support for method development and testing
- Collaborate closely with cross-functional teams to support research, formulation, and process development efforts
- Participate in integration of some assays into high-throughput/automated platforms
- Manage relationships with CROs & contribute to strategy for internal and external testing
- Author and review SOPs for analytical protocols, technical documents, and reports
Flagship Pioneering is a biotechnology company that fosters a culture of pioneering by creating platform companies focused on developing transformative human health and sustainability products. This ecosystem includes leaders such as Moderna and Tessera Therapeutics, leveraging cutting-edge biotechnologies to drive significant advancements in their fields. Working at this company offers the opportunity to be at the forefront of biotechnological innovation and to contribute to significant global challenges in health and sustainability.
Company Stage
N/A
Total Funding
$6.4B
Headquarters
Cambridge, Massachusetts
Founded
2000