Executive Director - Clinical Business Operations

About us

BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 10,000 colleagues spans five continents, with administrative offices in Basel, Beijing, and Cambridge, U.S. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn and X (formerly known as Twitter).

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.

Job Description:

General Description:

• As a global operational strategy and governance leader, drive operational excellence, financial stewardship, compliance, scalability, and digital transformation initiatives across Clinical Business Operations team.
• Oversee investigator budgets, site contracts, site payments, and budget data hub team to ensure precise budget forecasting, efficient site contract execution, timely and accurate site payments and budget data entry in databases.
• Responsible for CBO workforce planning, talent acquisition, succession planning, capability development, performance management, and fostering a high-performing, agile, and continuously improving team.

Essential Functions of the Job:

• Ensure alignment of regional execution strategies with global governance frameworks, including clear accountability models, decision-making processes, and issue escalation mechanisms across cross-functional and cross-country stakeholders.
• Establish and lead recurring governance cadences, including quarterly business reviews, escalation forums, and executive reporting to ensure risks, trends, and operational performance are proactively managed and communicated.
• Own and monitor key operational and financial performance indicators (KPIs) across investigator budgeting, site contracting, payments, and budget data governance functions, including but not limited to: Site contract cycle time and execution timeliness. Budget forecast accuracy and forecast vs. actual variance. Site payment timeliness and reconciliation accuracy.
• Provide strategic oversight of investigator fee budget planning activities to support accurate financial forecasting.
• Direct the development, review, negotiation, and timely execution of site budgets and clinical trial agreements in alignment within Fair Market value principles, study requirements, company standards, and study start-up timelines to support efficient operational delivery.
• Supervise the end-to-end site payment process and payment reconciliation process to ensure financial obligations are processed accurately and in accordance with contractual terms and payment schedules.
• Oversee the collection, validation, and maintenance of budget-related information within designated databases and systems to support data integrity and accuracy.
• Ensure all budget, contract, payment, and supporting operational documentation remains audit ready and compliant with applicable regulatory, financial, and internal governance standards.
• Maintain oversight of Sunshine reporting obligations and global transparency requirements, ensuring appropriate processes, controls and stakeholder alignment are consistently implemented across regions.
• Provide strategic oversight of outsourced vendors and external business partners, including performance monitoring, service quality oversight, issue escalation, and governance.
• Establish strong partnerships with Corporate Finance to drive financial governance, including oversight of accruals, forecast versus actual, and reconciliation processes.
• Oversee operational finances and team resources to ensure activities remain within approved budgets and resource allocations.
• Provide leadership, guidance, and performance management to team members, fostering accountability, collaboration, and continuous improvement.
• Support implementation of automation tools and digital solutions to improve overall productivity.

Qualification Required:

Qualifications:

• Strong planning and organizational skills and the ability to effectively leading team in a dynamic environment with competing priorities.
• Strong executive communication skills with ability to present data-driven insights to Senior leadership.
• Solution-driven and results-focused, with a willingness to dive deep and take a hands-on approach to work.
• Demonstrated ability to analyse complex financial data and translate insights into actionable guidance.
• Experience working cross-functionally with Clinical Operations, Finance, Payments, and Legal stakeholders.
• Advanced proficiency in Excel and data analytics tools; experience with budget systems and contract lifecycle management platforms preferred.
• Good knowledge of ICH-GCP, pharmaceutical related regulations and laws.

Supervisory Responsibilities: Yes
Computer Skills: Microsoft Office apps, PowerBI, or equivalent, CTMS, Contract Lifecycle Management System, Veeva, Sharepoint etc.

Travel: Yes, 10%

Education Required:

• Bachelor’s degree or above, in Life Sciences, Medical Science/ Medical, Finance, Health Economics, or related fields
• 20 + years of experience in Clinical operations, or study start-up, clinical site budgets, clinical site contracts, within a pharmaceutical sponsor or CRO environment.

What We Offer To Our Valued Employees

• Market competitive compensation package including performance-based annual bonus scheme

• Company shares (generous welcome grant!)

• In-house and external learning and development opportunities

• Fantastic benefits program and keep improving!

• Plus you get to work with a dynamic team of collaborative, supportive, inclusive, and fun professionals whose mission is clear: Cancer has no borders and neither do we.

• Join us and Make momentum in your career!

BeOne Global Competencies

When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

BeOne is committed to respect and protect personal information rights of job applicants and will process job applicants’ personal information in accordance with applicable laws and regulations.

Due to BeOne’s global operation, job applicants’ data will be stored overseas with adequate protection. Besides, job applicants’ data will be stored for no longer than is necessary to facilitate potential application for other suitable positions in BeOne. For further details, please refer to BeOne’s Job Applicant Privacy Policy (https://beonemedicines.com/privacy-policy).

If you voluntarily provide your personal information to us, it is deemed as you have acknowledged and consented to (if required by the applicable laws) BeOne’s Job Applicant Privacy Policy as well as the relevant privacy terms. If you voluntarily provide the personal information of other job applicants to us, it is deemed as you have ensured that the relevant individuals have acknowledged and consented to (if required by the applicable laws) BeOne’s Job Applicant Privacy Policy as well as the relevant privacy terms.

If you have any concern, please DO NOT provide any resume or other personal information to us.