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Genentech

Biotech firm creating medicines via R&D

Principal Scientist - Multiple Teams

Translational Research & Bench BiologyConfirmed live in the last 24 hours
Full-timeSouth San Francisco, CA, USA

About the Job

Requirements

  • A PhD and postdoctoral training in Immunology, Cell Biology, or a related field are required.
  • A minimum of 5 years of post-PhD experience is required, with a record of high-impact publications, preprints, patents, or a proven track record advancing therapeutic candidates from pipeline entry to early clinical development.
  • Demonstrated expertise in cellular immunology and a deep understanding of pathways and immune cell types that contribute to autoimmune disease are required.
  • Outstanding leadership and a collaborative approach, with a proven track record of working with multidisciplinary teams, are required.
  • Excellent written and verbal communication skills are required, including the ability to communicate complex scientific concepts to multidisciplinary audiences.
  • Exceptional critical thinking, rigorous experimental design, creative problem-solving, and the ability to use data-driven insights to guide scientific decisions are required.

Responsibilities

  • Lead and manage a highly productive research team focused on designing next-generation cell therapies for autoimmune diseases.
  • Integrate efforts across cross-functional teams to identify new targets and therapeutic hypotheses.
  • Advance transformative therapeutics from preclinical studies into early clinical development.
  • Generate high-quality, original research that advances understanding of autoimmune disease.
  • Contribute directly to the initiation and advancement of novel pipeline projects.
  • Participate in cross-functional teams evaluating external business development opportunities to accelerate the cell therapy pipeline.

Desired Qualifications

  • Expertise in both B cell and T cell biology.
  • Experience engineering, modifying, and functionally evaluating human immune cells.
  • Experience working with mouse models, including humanized models.

About the Company

Genentech

Biotech firm creating medicines via R&D

Genentech develops medicines and therapies to address unmet medical needs through extensive biotechnology research and development. Its products include biologic and small-molecule treatments prescribed by healthcare providers and sold through partnerships with suppliers and health systems. It differentiates itself with a large R&D footprint, a vast patent portfolio, and FDA Breakthrough Therapy Designations that accelerate promising therapies. Its goal is to advance medical science and deliver high-quality, effective therapies that improve patient health while supporting the broader medical community.

Company size
10,001+
Company stage
IPO
Headquarters
San Francisco, CA
Founded
1976

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