Full-Time

Senior AI Research Scientist/Engineer

Posted on 10/6/2025

System

System

11-50 employees

Causal, data-driven maps of complex systems

Compensation Overview

$200k - $220k/yr

Remote in USA + 1 more

More locations: New York, NY, USA

Hybrid

Category
AI & Machine Learning (2)
,
Required Skills
Scikit-learn
Python
Machine Learning
Java
C/C++
Requirements
  • M.S. or Ph.D. in Computer Science, Electrical Engineering, Statistics, or a related field; or equivalent industry experience.
  • Expertise in at least one major programming language (Python, C++, or Java), as well as strong experience with relational databases.
  • Familiarity with ML/DL model evaluation (e.g., accuracy, F1, BLEU, ROUGE, fairness metrics, latency) and human-in-the-loop processes.
  • Experience with benchmarking tools, evaluation libraries, and relevant frameworks (e.g., HuggingFace, OpenAI Evals, MLPerf, SciKit-learn, TensorFlow Model Analysis, or custom pipelines).
  • Strong expertise in scientific methods, experimental design, statistical analysis, and evaluation methodology.
  • Experience applying machine learning models to very large, complex datasets.
  • Experience with common machine learning frameworks, natural language processing and large language model toolkits.
  • Excellent communication and collaboration skills, with a proven ability to communicate results clearly to technical and non-technical audiences.
  • Strong problem-solving abilities and attention to detail.
  • Ability to be flexible, rational and open-minded.
  • Startup experience.
  • Experience with clinical healthcare data and knowledge of producing Real-World Evidence using data from Electronic Health Records.
Responsibilities
  • Work on cutting edge solutions in healthcare data modeling and contribute to innovation in AI and ML for Healthcare.
  • Work with System’s medical advisory staff to drive evaluation and clinical validation of System’s AI products and synthesize qualitative and quantitative insights to inform product and platform improvements.
  • Lead initiatives to design, and implement benchmarking frameworks to evaluate the performance, robustness, efficiency and clinical applicability of algorithms, models, and systems.
  • Develop and maintain evaluation metrics tailored to specific domains (e.g., NLP, computer vision, multi-modal systems, distributed systems).
  • Collaborate with cross-functional teams (researchers, engineers, product managers, medical staff) to define success criteria and validate new methods or architectures.
  • Draft white papers and peer-reviewed publications (and other technical communication) to highlight technical contributions and clinical impact of System’s products and platform.
  • Develop leadership skills and help to foster a culture of collaboration and continuous learning.
  • Influence culture and shape a rapidly growing startup.

System, Inc. helps people understand and address complex global problems by turning vast data into system maps. It builds data-driven graphical models that show how factors interrelate—starting with public health topics like COVID-19 and its links to diabetes and obesity—and aggregates thousands of sources, including peer-reviewed research, to illustrate cause-and-effect relationships. The platform is designed for researchers, policymakers, and the public to explore problems, identify intervention points, and make smarter decisions based on how events and conditions influence each other. What sets System apart is its focus on systems thinking and causal inference within a public benefit framework, plus a dedicated platform for visualizing knowledge graphs that connect data to real-world decisions. The company aims to improve collective understanding of complex systems and empower better actions by revealing interdependencies and intervention points across global issues.

Company Size

11-50

Company Stage

Grant

Total Funding

$19M

Headquarters

New York City, New York

Founded

2017

Simplify Jobs

Simplify's Take

What believers are saying

  • Wellcome's $6.5M investment funds System Graph release and researcher community building.
  • $12.25M funding from 18 investors including Lux Capital accelerates platform development.
  • $14.8M revenue with 18 employees signals strong growth in systems software.

What critics are saying

  • Wellcome locks PBC status for five years blocking profitable pivots.
  • Elicit and Consensus outperform System Pro eroding researcher market share.
  • Fragmented healthcare data causes System Graph accuracy failures triggering lawsuits.

What makes System unique

  • System visualizes complex challenges as interconnected systems graphs starting with public health.
  • System Pro offers AI-powered transparent search for health researchers synthesizing literature.
  • System Graph organizes scientific knowledge across silos into open-source tools.

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Benefits

Flexible Work Hours

Professional Development Budget

Growth & Insights and Company News

Headcount

6 month growth

10%

1 year growth

-8%

2 year growth

-8%
PR Newswire
Dec 16th, 2025
Wellcome invests $6.5M in System to organise scientific knowledge as interconnected graph

System, a Public Benefit Corporation building a quantitative model of the world as one interconnected system, has received a $6.5 million program-related investment from Wellcome Trust. This marks one of the foundation's first such investments in public interest technology. The funding will enable System to release the System Graph into the commons, develop open-source tools for researchers, and build a global community of systems thinkers. The System Graph aims to organise data and knowledge across traditional silos like disciplines and scales. Under the agreement, System must maintain its Public Benefit Corporation status for five years and cannot materially change its mission without Wellcome's approval. Founder and CEO Adam Bly said the investment ensures the company's mission remains durable and sustainable whilst driving systems-based research and solutions globally.

Business Wire
May 7th, 2024
Us Medical Innovations Secures Fda Clearance For Canady Helios Cold Plasma(Tm) Ablation System

TAKOMA PARK, Md.--(BUSINESS WIRE)--US Medical Innovations, LLC (USMI) announced today it has received FDA 510k Clearance (K240297) for the Canady Helios Cold Plasma™ (CHCP) Ablation System for the ablation of soft tissue during surgery. The CHCP system consists of the Canady Helios Cold Plasma XL-1000 CP Smart Electrosurgical Generator, Canady Helios Cold Plasma Ablators, Foot Pedal and Trolley Cart. Plasma is the fourth state of matter formed by ionizing neutral gases (i.e. Argon or Helium) combined with electromagnetic fields. The Canady Helios Cold Plasma™ System introduces a novel approach to soft tissue ablation using plasma. The system creates a plasma jet consisting of a pre-programmed, pulsed, non-contact, non-thermal (24 C to 30 C), three-dimensional, Plasma Treated Electromagnetic Field™ (PTEF)

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System, Inc. has expanded its Board of Directors with the appointments of Charles Ursini and Ryan Caswell as Class II and Class III directors, respectively.

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