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Beeline Medicines

Beeline Medicines

Clinical-stage biotech developing precision autoimmune therapies

Medical Science Liaison - Northeast

Full-Time
$165k - $235k/yr

+ Annual bonus + Long-term incentive/equity award

Mid, Senior
PharmD, PhD, MD
United States
Remote

The role is field-based within an assigned multi-state Northeast territory, with 50%+ travel and occasional overnight stays.

About the job

Requirements
  • An advanced degree—PharmD, PhD, or MD—in a relevant life sciences, pharmacy, or biomedical field.
  • A minimum of 3 years of MSL or related field-based medical affairs experience in the pharmaceutical or biotech industry for the MSL level.
  • A minimum of 5 years of MSL or field-based medical affairs experience in the pharmaceutical or biotech industry for the Senior MSL level.
  • Developing or advanced scientific and clinical knowledge of immunology and inflammation, including disease mechanisms, treatment landscapes, treatment algorithms, clinical trial endpoints, emerging therapeutic approaches, and the competitive I&I landscape, according to level.
  • Ability to interpret and communicate clinical, scientific, and translational data, including study design, statistical concepts, subgroup analyses, benefit-risk assessment, and evolving safety and efficacy profiles.
  • Working proficiency in customer relationship management platforms such as Veeva for field activity documentation, stakeholder mapping, and territory management.
  • Knowledge of medical affairs compliance frameworks, including Food and Drug Administration and European Medicines Agency regulations, Pharmaceutical Research and Manufacturers of America guidelines, on-label and off-label scientific exchange distinctions, and investigator-initiated study management frameworks.
  • Ability to operate a motor vehicle safely and successfully, with a valid United States driver's license and a driving record compliant with company standards.
  • Ability to travel 50% or more as needed, including occasional overnight stays.
  • Ability to work evenings and weekends as needed for physician or patient events, both in person and virtually.
  • Ability to manage a multi-state territory with a diverse customer base, depending on geography.
Responsibilities
  • Contribute to medical strategy through field insights and engagement with healthcare professionals, key medical experts, and investigators.
  • Develop and execute territory plans aligned with organizational priorities and data milestones.
  • Develop and manage relationships with key medical experts and healthcare professionals in the immunology and inflammation therapeutic area, including identifying, mapping, and engaging scientific thought leaders, clinical investigators, and academic centers relevant to the pipeline.
  • Develop segmentation, strategic engagement plans, and longitudinal relationship ownership for healthcare professionals, key medical experts, and investigators.
  • Conduct peer-to-peer scientific exchange by sharing clinical and preclinical data, presenting pipeline updates, and discussing unmet medical needs in a balanced, compliant, and scientifically rigorous manner.
  • Support clinical-trial awareness and site-identification efforts by engaging potential investigators and academic institutions and facilitating discussions that support site initiation and patient enrollment.
  • Serve as the scientific resource and company representative for clinical-site investigators from site start-up through study closeout in collaboration with Clinical Operations.
  • Respond to unsolicited medical-information requests in partnership with Medical Information and in accordance with regulatory and compliance guidelines.
  • Support investigator-initiated study activities by facilitating scientific discussions and coordinating with Medical Affairs leadership.
  • Identify evidence gaps and contribute to evidence-generation strategies.
  • Generate, synthesize, and translate field insights into strategic recommendations for Medical Affairs, Clinical Development, and cross-functional teams.
  • Represent the company at scientific conferences, medical congresses, and advisory board meetings and gather information that informs medical and pipeline strategy.
  • For the Senior MSL level, lead strategic territory and senior key-opinion-leader relationships, refine territory strategy, and allocate time and resources to maximize impact.
  • For the Senior MSL level, conduct sophisticated scientific exchange on emerging clinical data, benefit-risk considerations, and evolving disease paradigms.
  • For the Senior MSL level, support investigator identification, scientific site engagement, and enrollment-strategy discussions with Clinical Development and Clinical Operations.
  • For the Senior MSL level, own investigator-initiated study relationships, facilitate the review process, and maintain scientific engagement with funded sites.
  • For the Senior MSL level, present strategic key-opinion-leader engagement insights and field intelligence to influence organizational decision-making.
  • For the Senior MSL level, contribute to scientific training materials, field tools, and disease-area resources.
  • For the Senior MSL level, contribute to advisory board development and execution, including expert identification, agenda input, and synthesis of outcomes into recommendations.
Desired Qualifications
  • Post-doctoral training, clinical fellowship, or residency in a relevant discipline.
  • Experience in immunology, inflammation, or a related therapeutic area.
  • Clinical-stage biotechnology experience.
  • Prior involvement in investigator-initiated study management or clinical-trial support activities.
  • Experience with digital engagement platforms and virtual scientific exchange.
  • Experience leveraging artificial intelligence-driven and omnichannel engagement strategies.

About the company

Beeline Medicines is a clinical-stage biotechnology company focused on precision therapies for autoimmune and inflammatory diseases, formed after in-licensing five programs from Bristol Myers Squibb with a $300 million Series A led by Bain Capital. Its lead programs include afimetoran, an oral lupus therapy that inhibits TLR7 and TLR8, lomedeucitinib, an allosteric TYK2 inhibitor, and two IND-stage biologics targeting IL-18 and IL-10 pathways. The drugs work by modulating specific immune signaling pathways to reduce inflammation, with afimetoran designed to address lupus drivers. The company differentiates itself by using in-licensed assets from a major pharma partner and combining them with an experienced leadership team to push multiple programs toward pivotal trials, starting with Phase 2 for afimetoran targeted for late 2026.

Company Size

51-200

Company Stage

Series A

Total Funding

$426.3M

Headquarters

Stamford, Connecticut

Founded

2025

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Simplify's Take

What believers are saying

  • Beeline closed a $126.3 million extension on June 30, 2026, reaching $426.3 million.
  • FDA Fast Track for afimetoran in May 2025 accelerates regulatory interaction.
  • Management plans several clinical starts within 12 months, expanding catalysts beyond lupus.

What critics are saying

  • Afimetoran’s Phase 2 lupus readout in H2 2026 is the company’s make-or-break catalyst.
  • Failure versus Benlysta, Saphnelo, and competing lupus drugs kills the pivotal plan.
  • Five BMS-origin assets concentrate scientific risk; one bad readout can crush financing appetite.

What makes Beeline Medicines unique

  • BMS licensed five programs to Beeline in 2025, de-risking discovery.
  • Afimetoran targets TLR7/8, an upstream lupus mechanism unlike downstream cytokine biologics.
  • Saqib Islam and SpringWorks veterans bring repeatable biotech execution and exit experience.

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Benefits

Remote Work Options

Flexible Work Hours

Paid Vacation

Paid Holidays

Health Insurance

Company Equity

Performance Bonus

Growth & Insights and Company News

Headcount

6 month growth

-8%

1 year growth

-8%

2 year growth

-8%
Beeline Medicines
Jun 30th, 2026
Terms of Use - Beeline Medicines

Terms of Use Agreement Effective: April 8, 2026 1. Acceptance of the Terms and Conditions. Beeline Medicines Corporation (herein referred to as “Beeline,” “we,” “us” or “our”) provides and makes available this web site (the “Web Site”). All use of the Web Site is subject to the terms and conditions contained in this Terms of […]

Fierce Biotech
Jun 29th, 2026
BMS-backed Beeline raises $126M series A extension for autoimmune programs

Beeline Medicines has raised $126.3 million in a Series A extension, just two and a half months after emerging from stealth with $300 million in funding and five autoimmune programmes from Bristol Myers Squibb. The biotech startup, backed by BMS, is developing treatments targeting autoimmune diseases. The additional funding comes as the company rapidly advances its pipeline following its December debut. Details about the extension round's investors and the company's specific plans for the new capital were not disclosed.

Yahoo Finance
Apr 15th, 2026
Beeline debuts with $300M and immune drugs licensed from Bristol Myers

Beeline Medicines emerged from stealth with $300 million in Series A funding from Bain Capital to develop precision therapies for immune diseases. The company's pipeline includes five experimental medicines licensed from Bristol Myers Squibb nearly a year ago. Beeline's lead asset is afimetoran, a daily oral treatment for systemic lupus erythematosus targeting immune system receptors. A Phase 2 study is expected to complete in the second half of this year, with a pivotal programme planned thereafter. The pipeline also includes candidates for atopic dermatitis, lupus and plaque psoriasis, plus two preclinical assets. Saqib Islam, former CEO of SpringWorks Therapeutics, leads the company. Bain Capital previously backed Cerevel Therapeutics, acquired by AbbVie for nearly $9 billion, and Aiolos Bio, purchased by GSK.

Dealroom.co
Apr 15th, 2026
Beeline Medicines company information, funding & investors

Beeline Medicines, precision therapies for autoimmune and inflammatory diseases. Here you'll find information about their funding, investors and team.

GlobeNewswire
Apr 15th, 2026
Beeline Medicines Debuts to Deliver Category-Leading Precision Therapies for People Living with Autoimmune and Inflammatory Diseases

– Advancing a broad portfolio designed to deliver multiple paradigm-shifting therapies for devastating and underserved immune-mediated diseases –  – Lead...