Senior Scientist, Method Development (Regulated Bioanalysis) - Method Development, Regulated Bioanalysis

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Position Summary

The position will be responsible for evaluating and implementing bioanalytical methods in the development stage. The individual will provide leadership on the BA/biomarker method development, validation, and study support of development compounds from various modalities (small molecule, large molecule therapeutics, etc.) mainly using LC-MS technology. In addition, the candidate will play a critical role as an expert in the evaluation advanced laboratory equipment. There are also development opportunities to act as a BA or biomarker lead on cross-functional study teams, and work with them to address bioanalytical and biomarker-related issues. 

Key Responsibilities

• Evaluate and apply novel techniques or approaches to address challenging bioanalytical and biomarker issues.

• Conduct in-house bioanalytical and biomarker support for development programs with tandem mass spectrometry-based method development, validation, sample analysis, data interpretation, to report preparation in a regulated laboratory.

• Be the technical expert on sample cleanup, chromatography, mass spectrometric instrumentation, stability, and other method related issues.

• Interact with bioanalytical CROs to address method related issues and provide leadership for the knowledge transfer of novel technologies.

• Keep management apprised of project status and current scientific trends using written and oral summaries, as well as presentations.

Qualifications & Experience

• Ph.D. or equivalent advanced degree in the Life Sciences
• 2+ of academic and / or industry experience
• Ph.D. or equivalent advanced degree in the Life Sciences
• 4+ of academic and / or industry experience
• Preferred candidate will have a degree in chemistry, biochemistry, biology or related fields, plus relevant drug development experience at either a pharmaceutical company or a bioanalytical & biomarker CRO.
• A good understanding of bioanalysis & biomarker and their roles in drug development, including method development, validation, study support, and impact of quality bioanalytical/biomarker data to PK/PD correlation.
• Strong LC-MS/MS skills with separation and quantitation (or identification) of small (e.g. chiral assays) or large molecule therapeutics (e.g. hybrid assays for ADCs) and biomarkers (e.g. small molecule/protein assays) in biological matrices. A strong foundation and experience in using, maintaining, and trouble-shooting mass spectrometers is preferred.
• Experiences in performing LC-MS/MS and LBA method development, qualification/validation, and study sample analysis in a regulated environment to support preclinical and clinical studies with compliance.
• A proven track record of method development accomplishments in the field (thru presentations or publications).
• Good communication skills and experience in authoring and reviewing bioanalytical & biomarker assay, troubleshooting assay issues and direct junior scientist.
• Ability to multi-task and work in a collaborative team environment.

• Ability to communicate effectively in a team-based environment.

#LI-Onsite

We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

Princeton - NJ - US: $117,170 - $141,986 


The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits:

Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).

U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.

Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.

Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.

U.S.-based job seekers can explore full benefit offerings athttps://careers.bms.com/benefits

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only:  If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

For roles based in Washington State only: If you live in or expect to work from Washington State if hired for this position, please visit this page for important information about the Washington Fair Chance Act.

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at [email protected]with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1608002 : Senior Scientist, Method Development (Regulated Bioanalysis)