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UntilLabs

Advances reversible organ cryopreservation technology

Lab Technician

Translational Research & Bench BiologyConfirmed live in the last 24 hours
Full-timeSan Francisco Bay Area, CA, USA$70k - $90k /yr

About the Job

Requirements

  • A bachelor's degree in Biology, Biochemistry, Bioengineering, Molecular Biology, Chemistry, or a related field is required.
  • At least two years of hands-on laboratory experience, including relevant academic research, internships, or industry experience, is required.
  • Hands-on experience with molecular biology and protein purification is required.
  • Familiarity with SDS-PAGE, protein concentration assays, accurate pipetting, solution preparation, and routine laboratory calculations is required.
  • Familiarity with aseptic technique, laboratory safety, and contamination-control practices is required.
  • Strong organization, attention to detail, and documentation skills are required, with the ability to follow protocols, coordinate multiple tasks, and communicate deviations.

Responsibilities

  • Express recombinant proteins in E. coli and yeast using established protocols, including culture preparation, growth, induction, and harvesting.
  • Purify proteins using affinity chromatography, concentration, and buffer exchange.
  • Assess protein concentration, yield, and purity using SDS-PAGE and protein concentration assays.
  • Prepare and replenish culture media, buffers, stock solutions, and experimental reagents, including accurate weighing, dilution, pH adjustment, and sterilization as appropriate.
  • After training, handle and maintain mammalian cells, including thawing, media changes, passaging, cell counting, viability assessment, and cryopreservation.
  • Monitor cell morphology, confluency, and culture health; follow aseptic practices and promptly report contamination or unexpected results.
  • Label, store, and track proteins, reagents, and cell stocks, maintaining clear records of preparation, production, quality control, and cell maintenance.

Desired Qualifications

  • Experience expressing recombinant proteins in both E. coli and yeast.
  • Experience with chromatography systems.
  • Experience with larger-scale protein production and batch control.
  • Experience with routine mammalian cell handling and maintenance.
  • Strong protein-production experience with an interest in learning routine mammalian cell handling and maintenance techniques.

About the Company

UntilLabs

Advances reversible organ cryopreservation technology

UntilLabs develops reversible cryopreservation technology to extend the viability of human organs for transplantation. The goal is to keep organs alive at cryogenic temperatures long enough to improve organ matching and reduce waste from time limits, potentially weeks or months of preserved time. The approach uses cooling to very low temperatures (below -130°C) with cryoprotectants to prevent ice damage, followed by advanced warming methods to revive the organs without harm. While cryopreservation has worked for cells and simple tissues, UntilLabs works on scaling this to whole organs, tackling challenges like ice formation and nutrient/waste management in large tissues. In the long term, the company envisions whole-body reversible cryopreservation as a bridge to future medical cures.

Company size
51-200
Company stage
Series A
Total funding
$58M
Headquarters
San Francisco, CA
Founded
2024

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