Clinical Research Nurse Coordinator

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Duke Cancer Institute (DCI) is seeking a Clinical Research Nurse Coordinator to join our team supporting oncology clinical trials at our Wake County Cancer Center locations. In this role, you will lead and coordinate multiple, complex clinical research studies, playing a critical role in advancing cancer care through innovative research.

You will work closely with Principal Investigators (PIs), study teams, and participants to ensure studies are conducted efficiently, ethically, and in compliance with regulatory standards. Daily, you will engage directly with patients, coordinating study visits, administering study-related care, and ensuring participants are supported throughout their research journey.

This is a highly collaborative and impactful role where you will combine your clinical expertise with research coordination, contributing to study development, managing regulatory requirements, and helping bring new treatments to patients. You will also serve as a mentor and resource to colleagues while actively participating in ongoing learning, research presentations, and professional development opportunities.

Minimum Requirements:

• Graduation from an accredited BSN program, or Associate Degree in Nursing, or Nursing Diploma program
• Current or compact RN licensure in the state of North Carolina
• BLS certification required
• Twelve months of appropriate clinical nursing experience
• Registered nurses without a Bachelor’s degree in Nursing must enroll in a BSN program within two years of hire and complete within seven years
• Maintain compliance with hospital and unit-specific training competencies and active RN status with the North Carolina Board of Nursing (NCBON)

Preferred Qualifications:

• Oncology and/or clinical research experience
• Experience coordinating clinical trials or working in a research environment
• Familiarity with regulatory documentation, study protocols, and compliance standards
• Experience using Electronic Data Capture (EDC) systems

Other Requirements:

• Strong proficiency in Microsoft Office and web-based applications
• Ability to manage multiple complex studies simultaneously
• Strong communication, organizational, and problem-solving skills
• This position is onsite, supporting Duke Cancer Institute operations at Wake County Cancer Center locations

Be Bold.

Position Description:

• Coordinate and manage complex oncology clinical trials, including study start-up, participant recruitment, enrollment, visit scheduling, and study closeout activities
• Collaborate with Principal Investigators and study teams to conduct informed consent, assess patient eligibility, and ensure successful study execution
• Maintain regulatory and study documentation, including regulatory binders, delegation logs, enrollment tracking, adverse event reporting, and compliance with institutional and federal requirements
• Administer clinical care within research protocols, including medication administration, chemotherapy delivery, patient education, and monitoring for adverse events or protocol compliance
• Analyze recruitment, retention, and study processes, identify challenges, and implement solutions to improve study performance and participant engagement

Additional responsibilities include:

• Serving as a liaison between sponsors, study teams, and leadership
• Supporting financial oversight, including study budgets, billing compliance, and milestone tracking
• Ensuring accurate and timely data entry and data integrity within EDC systems
• Participating in site initiation, monitoring, and closeout visits
• Mentoring staff and contributing to team leadership, committees, and professional development initiatives
• Supporting ethics and compliance standards by educating patients and staff on research versus clinical care distinctions

Choose Duke.

At Duke Cancer Institute, you’ll be part of a nationally recognized leader in cancer care, research, and innovation. Our Wake County Cancer Center locations bring cutting-edge treatments and clinical trials closer to our communities, ensuring patients have access to the latest advancements in oncology.

Joining our team means collaborating with world-class physicians, researchers, and clinicians who are committed to improving patient outcomes and transforming the future of cancer care. You’ll work in an environment that values compassion, discovery, and excellence—where your contributions directly impact patients’ lives.

Duke University is consistently ranked among the top academic and healthcare institutions in the world. As part of our team, you’ll benefit from a culture that supports professional growth, continuing education, and career advancement.