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Ascendis Pharma

Biopharmaceutical company developing long-acting prodrugs

Head of IT Compliance

Regulatory & Quality (Life Sciences)Confirmed live in the last 24 hours
Full-timeHellerup, DenmarkNo salary listed

About the Job

Requirements

  • A relevant academic degree and extensive experience in regulated pharmaceutical or life-science environments, ideally including 10 or more years in IT compliance, quality, validation, or related disciplines.
  • Leadership experience combining strategic direction with practical support to teams and stakeholders.
  • Strong experience with GxP, pharmaceutical IT compliance, computer system validation, validation planning, testing, test execution, and quality assurance.
  • Knowledge of SOX controls and regulatory frameworks including 21 CFR Part 11, EudraLex Volume 4 Annex 11, GAMP 5, the EU AI Act, NIS2, and European data privacy regulations.
  • Technical understanding and the ability to translate complex regulatory expectations into practical guidance for IT professionals.
  • Experience supporting agile product and platform teams while maintaining regulatory oversight and a risk-based approach.
  • Experience developing people through leadership, coaching, training, and knowledge sharing, and building trusted relationships across functions and geographies.
  • Ability to manage priorities independently and communicate effectively with highly skilled IT professionals.
  • Up-to-date understanding of evolving regulatory expectations and sound judgment, critical thinking, and risk-based decision making.
  • Applications must be submitted in English.

Responsibilities

  • Lead and further develop the IT Compliance function, set direction, develop team capabilities, and foster a culture of quality, learning, and critical thinking.
  • Partner with IT Product and Platform teams in GxP-regulated environments to enable compliant, efficient, business-focused delivery.
  • Advise leaders and stakeholders on IT compliance, quality management, computer system validation, testing, and applicable regulatory requirements.
  • Drive the evolution of the IT Quality Management System, governance frameworks, and compliance processes, including SOX controls.
  • Monitor and assess emerging regulatory requirements and incorporate relevant changes into IT policies, standards, procedures, and ways of working.
  • Advance continuous compliance principles, shift-left testing approaches, and agile methodologies across Global IT.
  • Build compliance capabilities through training, coaching, knowledge sharing, and awareness initiatives.
  • Combine strategic leadership with hands-on execution and contribute to the function’s delivery and success.
  • Champion critical thinking and a strong quality mindset, challenge unnecessary complexity, and create clarity and confidence for the team and stakeholders.

Desired Qualifications

  • Ideally, 10 or more years of experience in IT compliance, quality, validation, or related disciplines.

About the Company

Ascendis Pharma

Biopharmaceutical company developing long-acting prodrugs

Ascendis Pharma uses its TransCon technology to create long-acting prodrugs for rare endocrine diseases, with expansions into oncology and ophthalmology. The platform temporarily attaches an unmodified drug to an inert carrier and releases the active drug in a predictable, sustained way after injection, reducing how often patients must dosing. It differentiates itself through a proprietary delivery system and a track record that includes marketed therapies like SKYTROFA for pediatric growth hormone deficiency and YORVIPATH for hypoparathyroidism, along with collaborations such as a Novo Nordisk deal. The company aims to improve patient outcomes by enabling easier, less frequent dosing while expanding its pipeline across rare endocrine diseases, cancer, and eye diseases.

Company size
1,001-5,000
Company stage
IPO
Headquarters
Gentofte Municipality, Denmark
Founded
2007

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